Assuntos
Carcinoma de Apêndice Cutâneo , Neoplasias de Tecido Conjuntivo , Neoplasias Cutâneas , Neoplasias das Glândulas Sudoríparas , Masculino , Humanos , Adulto Jovem , Adulto , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/patologia , Carcinoma de Apêndice Cutâneo/patologia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologia , Glândulas Écrinas/patologiaAssuntos
Carcinoma de Apêndice Cutâneo , Neoplasias Cutâneas , Neoplasias das Glândulas Sudoríparas , Carcinoma de Apêndice Cutâneo/patologia , Demografia , Humanos , Mucinas , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/epidemiologia , Neoplasias Cutâneas/patologia , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/epidemiologia , Neoplasias das Glândulas Sudoríparas/patologia , Glândulas Sudoríparas/patologiaRESUMO
Epidermodysplasia verruciformis (EV) is a rare, life-long heritable disease caused due to a unique susceptibility to human papilloma virus. The disseminated verrucous lesions and pityriasis versicolor-like lesions persist from early childhood and can transform into a cutaneous malignancy in a fourth of patients. Malignant transformation into syringoid eccrine carcinoma (SEC) has been reported only once so far. SEC is an extremely invasive, rare, locally destructive, slowly growing adnexal tumor. We hereby report the association of EV with SEC in a 29-year-old male.
Assuntos
Carcinoma de Apêndice Cutâneo/patologia , Epidermodisplasia Verruciforme/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Adulto , Carcinoma de Apêndice Cutâneo/complicações , Transformação Celular Neoplásica , Epidermodisplasia Verruciforme/complicações , Humanos , Masculino , Papillomaviridae , Neoplasias das Glândulas Sudoríparas/complicaçõesAssuntos
Carcinoma de Apêndice Cutâneo/patologia , Epiderme/patologia , Hanseníase/patologia , Mycobacterium leprae/isolamento & purificação , Neoplasias Cutâneas/patologia , Adulto , Carcinoma de Apêndice Cutâneo/microbiologia , Epiderme/microbiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Cutâneas/microbiologia , Adulto JovemRESUMO
BACKGROUND: Appendageal skin tumors belong to a heterogenous group of tumors with specific histopathology. The aim of this study is to determine the pattern of appendageal tumors in skin biopsies done in our department. METHODS: This is a 3-year retrospective descriptive study of all patients who were diagnosed to have skin appendageal tumors in our department, and the diagnoses were confirmed by histopathology. The tumors were classified as eccrine, hair, sebaceous, and apocrine after a detailed examination of routine hematoxylin and eosin sections. RESULTS: The total number of cases in the study was 33-10 males and 23 females. Tumors with eccrine differentiation constituted the maximum, 17 cases (51.5%); followed by tumors with hair differentiation, 12 cases (36.36%); tumors with sebaceous differentiation, 2 cases (6.06%); and apocrine tumors, 2 cases (6.06%). Syringoma constituted the commonest eccrine tumor, 14 cases (42.42%); while trichoepithelioma was the commonest hair tumor, 9 cases (27.27%). The other eccrine tumors were eccrine spiradenoma, 2 cases (6.06%); and nodular hidradenoma, 1 (3.03%). The other hair tumors were pilar cyst, 2 (6.06%); and pilomatricoma, 1 (3.03%). The sebaceous tumors constituted 2 cases (6.06%) of nevus sebaceous. Syringocystadenoma papilliferum, 1 (3.03%); and cylindroma, 1 (3.03%), constituted the apocrine tumors. CONCLUSIONS: Appendageal skin tumors are relatively uncommon. Histopathology is mandatory for the diagnosis. No tumor showed malignant change in this study.