RESUMO
The occurence of squamous cell carcinoma on long-lasting ulcers is classic. Malignant transformation may occur on burn scars and chronic ulcers of varying etiology, including infectious agents. Transformation of old lobomycosis lesion scars into squamous cell carcinoma has been rarely reported. Careful and long-term follow-up of such patients is important to avoid carcinomatous transformation.
A ocorrência de carcinoma espinocelular sobre lesões cutâneas de longa evolução é clássica em cicatrizes de queimadura e úlceras crônicas de etiologia variada, inclusive infecciosa. Na literatura, são raros os casos de pacientes com lobomicose de longa evolução que desenvolveram CEC. O seguimento cuidadoso desses pacientes é importante, pois, nas áreas de traumas, ulcerações e cicatrizes crônicas pode ocorrer degeneração carcinomatosa. .
Assuntos
Idoso de 80 Anos ou mais , Humanos , Masculino , Carcinoma de Células Escamosas/patologia , Lobomicose/patologia , Neoplasias Cutâneas/patologia , Carcinoma de Células Escamosas/etiologia , Cicatriz/patologia , Lobomicose/complicações , Neoplasias Cutâneas/etiologiaRESUMO
The development of squamous cell carcinoma in long-established ulcers is described in two patients with leprosy, one on the lower leg in a patient with borderline-tuberculoid (BT) leprosy and the other on the sole of the foot in a patient with lepromatous (LL) leprosy. Although sometimes stated by clinicians to be rare, and infrequently reported in the literature, it is suggested that malignant change in chronic ulcers in leprosy may be found more often if patients are examined with care and the possibility kept in mind.
Assuntos
Masculino , Feminino , Humanos , Pessoa de Meia-Idade , Carcinoma de Células Escamosas/etiologia , Doenças do Pé/complicações , Hanseníase/complicações , Neoplasias Cutâneas/etiologia , Úlcera da Perna/complicações , Úlcera/complicaçõesRESUMO
Exophytic neoplasms arise rarely in neurotrophic ulcers of leprosy. When such a lesion does develop, it has clinical resemblance to an indolent and locally invasive epithelioma cuniculatum, may invade deeply, and may metastasize. The case described showed deep invasion and extensive involvement of bone. Exophytic neoplasms in neurotrophic ulcers of leprosy should be considered to be squamous-cell carcinomas, not epitheliomata cuniculata, because of their potential for rapid, deep invasion and metastases.