1.
Chem Commun (Camb)
; 51(86): 15728-31, 2015 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26364768
RESUMO
Key residues of Debaryomyces hansenii carbonyl reductase in the determination of the reducing activity towards aryl haloketones were identified through combinatorial mutation of conserved residues. This study provides a green and efficient biocatalyst for the synthesis of (S)-aryl halohydrins.