Assuntos
Neoplasias Encefálicas/complicações , Glioblastoma/complicações , Doenças do Cabelo/complicações , Pilomatrixoma/complicações , Neoplasias Cutâneas/complicações , Feminino , Doenças do Cabelo/patologia , Humanos , Neoplasias Primárias Múltiplas/patologia , Pilomatrixoma/patologia , Neoplasias Cutâneas/patologia , Adulto JovemAssuntos
Doenças do Cabelo/diagnóstico , Hemocromatose/diagnóstico , Melanose/diagnóstico , Diagnóstico Diferencial , Doenças do Cabelo/complicações , Hemocromatose/complicações , Humanos , Melanócitos/patologia , Melanose/complicações , Piebaldismo/complicações , Piebaldismo/diagnóstico , Transtornos da Pigmentação/complicações , Transtornos da Pigmentação/diagnósticoRESUMO
A 10-month-old female presented with severe progressive wedge-shaped thickening and discoloration of all twenty nails. Further evaluations revealed palmoplantar keratoderma along with recurrent acral blisters causing residual crusted ulcers which were present during the past six months. Other findings included scalp kinky hair and dental caries. Past medical and family history had remarkable findings such as natal teeth and similar skin lesions in her older brother since his infancy. The patients' clinical presentations and history are compatible with pachyonychia congenita presenting with concomitant features of both subtypes 1 and 2.
Assuntos
Doenças do Cabelo/complicações , Doenças do Cabelo/diagnóstico , Paquioníquia Congênita/complicações , Paquioníquia Congênita/diagnóstico , Feminino , Doenças do Cabelo/genética , Humanos , Lactente , Paquioníquia Congênita/genéticaRESUMO
To describe eyelid changes in ocular leprosy, 74 patients (148 eyes or 296 eyelids) were examined, focusing on eyelid abnormalities. The adnexal examination included evaluation of the upper eyelid crease pattern, qualitative assessment of the orbicularis oculi muscle function, measurement of the distance between the corneal reflex and the upper eyelid margin (margin reflex distance), and slit-lamp biomicroscopy of the eyelashes and tarsal conjunctiva. Eyelash ptosis was a common finding associated with a multiple upper eyelid crease pattern and trichiasis. In the past, eyelash ptosis has probably been diagnosed as upper eyelid entropion or trichiasis, but in this series entropion was not observed. The distinction between eyelash ptosis, trichiasis, and upper eyelid entropion is important because the surgical management for each is different. Other true leprotic abnormalities of the eyelids are lagophthalmos and lower lid ectropion.