Assuntos
Dermatomicoses/microbiologia , Edema/microbiologia , Doenças do Pênis/microbiologia , Zigomicose/complicações , Anti-Infecciosos/uso terapêutico , Pré-Escolar , Dermatomicoses/tratamento farmacológico , Humanos , Masculino , Doenças do Pênis/tratamento farmacológico , Iodeto de Potássio/uso terapêutico , Zigomicose/diagnóstico , Zigomicose/tratamento farmacológicoRESUMO
BACKGROUND: Erythema nodosum leprosum (ENL) classically presents as tender evanescent skin nodules involving extremities, trunk, and face but may appear at any site. Mucosal involvement in ENL is uncommon, and its occurrence over glans is extremely rare. METHOD: We describe two interesting cases of ENL involving the glans penis and prepuce with different presentations. RESULT: The first case had lepromatous leprosy with ENL with involvement of the glans penis in the form of a painful ulcer with necrotic slough. The second case had borderline lepromatous leprosy with ENL with involvement of glans in the form of a single painful nodule. Histopathology showed features of ENL, and Ziehl-Neelsen staining showed numerous acid fast bacilli. CONCLUSION: We should be aware of genital involvement of ENL, which is a rare presentation and needs to be differentiated from other conditions requiring a different management approach.
Assuntos
Eritema Nodoso/patologia , Hanseníase Virchowiana/patologia , Mycobacterium leprae/isolamento & purificação , Doenças do Pênis/microbiologia , Pênis/patologia , Adulto , Quimioterapia Combinada , Eritema Nodoso/diagnóstico , Eritema Nodoso/tratamento farmacológico , Seguimentos , Humanos , Imuno-Histoquímica , Hanseníase Virchowiana/diagnóstico , Hanseníase Virchowiana/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Doenças do Pênis/tratamento farmacológico , Doenças do Pênis/patologia , Medição de Risco , Estudos de Amostragem , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
Skin lesions in lepromatous leprosy (LL) are usually multiple and widespread. Though the lesion may occur anywhere on the skin, male genitalia is rarely involved. In all cases reported so far about penile lesions of LL, there were lesions on the other parts of the body also. In some of the cases scrotum was also involved. We report here a patient who presented himself with a single macular lesion of leprosy on the shaft of his penis diagnosed as a case of lepromatous leprosy on slit-skin smear and histopathological examinations.
Assuntos
Hanseníase Virchowiana/patologia , Mycobacterium leprae/crescimento & desenvolvimento , Doenças do Pênis/microbiologia , Dermatopatias/metabolismo , Adulto , Humanos , Hansenostáticos/uso terapêutico , Hanseníase Virchowiana/tratamento farmacológico , Hanseníase Virchowiana/microbiologia , Masculino , Doenças do Pênis/tratamento farmacológico , Doenças do Pênis/patologia , Dermatopatias/tratamento farmacológico , Dermatopatias/patologiaRESUMO
A 5-year-old contact of a lepromatous leprosy patient with a tuberculoid lesion on the anterior aspect of the shaft of the penis is reported. The child was clinically suspected to have borderline tuberculoid leprosy during a survey of contacts of leprosy patients, which on histopathology revealed features of subpolar tuberculoid leprosy. The father of the child was recently detected as a case of lepromatous leprosy and was started on multibacillary regime of WHO multidrug therapy. The reason for the localization of the lesion to the shaft of the penis is also suggested. Skin as a route of transmission of tuberculoid leprosy is also emphasized.
Assuntos
Hanseníase Tuberculoide/diagnóstico , Doenças do Pênis/diagnóstico , Doenças do Pênis/microbiologia , Pré-Escolar , Humanos , Hanseníase Tuberculoide/tratamento farmacológico , Hanseníase Tuberculoide/patologia , Masculino , Doenças do Pênis/tratamento farmacológico , Doenças do Pênis/patologiaRESUMO
Two cases of pyoderma gangrenosum involving the penis are presented. Treatment was difficult in both cases despite the use of high doses of prednisolone. In one case, the addition of thalidomide proved successful, whereas in the other, minocycline effected a cure.