Afectación cutánea en las micosis profundas: una revisión de la literatura. Parte 1: micosis subcutáneas / Cutaneous involvement in the deep mycoses: a literature review. Part I-subcutaneous mycoses

Las micosis profundas son infecciones poco frecuentes en nuestro medio. Se presentan principalmente en pacientes inmunodeprimidos o en regiones de climas tropicales, que abarcan las micosis subcutáneas y las micosis sistémicas. Las micosis subcutáneas o por implantación siempre producen signos de afectación cutánea. En la primera parte de esta revisión se realizará una revisión de las principales micosis subcutáneas: esporotricosis, cromoblastomicosis, micetomas, feohifomicosis, hialohifomicosis y lacaziosis. Reconocer y tratar estas micosis subcutáneas de forma precoz es importante, ya que a menudo están asociadas a una alta morbilidad

The deep mycoses are uncommon in our setting. These fungal infections occur mainly in immunosuppressed patients or in tropical climates, and include subcutaneous infections and systemic infections. The skin is always involved in the former. In the first part of this review, we describe the main subcutaneous mycoses: sporotrichosis, chromoblastomycosis, mycetoma, phaeohyphomycosis, hyalohyphomycosis, and lacaziosis. Early recognition and treatment is important, as these infections are frequently associated with high morbidity

Criptococosis cutánea asociada a la lepra lepromatosa / Cutaneous cryptococcosis associated with lepromatous leprosy

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ICAAC update on opportunistic infections.

AIDS: Recent research on the effects of opportunistic infections (OIs) on HIV replication suggests that the OIs can actually increase HIV replication through the production of cytokines. Treatment options for thrush include antifungal treatments for early episodes and reserving fluconazole for patients with difficult to treat infections. Other studies show that prevention and treatment of Mycobacterium avium complex (MAC) increases survival rates. Drugs and dosages are described.^ieng

Itraconazole and fluconazole in three neuro-paracoccidioidomycosis patients / Itraconazol e fluconazol em 3 pacientes com neuro-paracoccidioidomicose (PBM) cerebral

Three paracoccidioidomycoses (OBM) patients: Male, age 44,51 and 53 years old, form workers, heavy smokers, alcoholics were admitted in to Emílio Ribas Hospital, Såo Paulo, SP, with dyspnea, expectorative cough in all of them and evolutive cardiac edema in two C.O.P.D. inpatients. Hypertensive / nephropathy - 2, adenopathy - 2, clubbing finger, Cor pulmonale (C.O.P.D.), hepatoesplenomegaly and severe interstitial bilateral infiltrate lung lesions were related in 2 patients. Encephalopaty and cerebelar ataxia in one, focal convulsive crises, hypoastesia right arm and Mingazzini neurologic examens were observed in two patients. Paracoccidioides brasiliensis was recovered from bronchoscopy. Pulmonary function showed: bronchodilator no response and 2 mixels test, hypergamaglobulinemia, increases seric level alcaline phosphatase in 3, policytemia in 2 and complement fixation reaction rancing from 1/8 to 1/64 with negative counter immunoelectrophoresis, like laboratorial examens. Berebral C.T. -scan confirmed active nodules in three and cerebelar abscess in one. Azoles therapy revealed one early deth and after 18 months the presence of active nocules (C.T.-scan skull) in 2 of all chronic lung PBM patients