Assuntos
Dermatoses da Mão/patologia , Histiocitoma Fibroso Benigno/patologia , Histiocitoma Fibroso Maligno/patologia , Neoplasias Cutâneas/patologia , Biópsia por Agulha , Seguimentos , Dermatoses da Mão/diagnóstico , Histiocitoma Fibroso Benigno/diagnóstico , Histiocitoma Fibroso Maligno/diagnóstico , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , Doenças Raras , Medição de Risco , Neoplasias Cutâneas/diagnóstico , Conduta ExpectanteRESUMO
BACKGROUND: Dermatofibroma sometimes clinically presents as a nodular lesion without gross skin surface change. Clinicopathologic features of this variant of dermatofibroma have not been evaluated. AIMS: To assess clinicopathologic features of dermatofibroma presenting as a subcutaneous nodule. METHODS: This study reviewed the clinical and histological features of 42 cases of subcutaneous dermatofibromas and compared them with 95 cases of conventional dermatofibroma. RESULTS: Dermatofibroma without gross skin surface change was associated with a shorter pre-diagnosis duration than conventional dermatofibroma. Increase in size during the pre-diagnosis period was significantly more frequent in the conventional type. In addition, these dermatofibromas were more likely than the conventional type to occur in the head and neck region. Although tumor depth was deeper than in the conventional type, less than half of the dermatofibromas without gross skin surface change were found histologically to be "subcutaneous" or "deep-penetrating dermatofibroma". Subcutaneous extension was more frequent in these dermatofibromas while focal stromal hyalinization and hemosiderin deposits were more common in the conventional type. LIMITATIONS: This study is a retrospective, single center design. CONCLUSION: The present study suggests that dermatofibroma without gross skin surface change is a variant type with distinct clinical and histological features that distinguish them from conventional dermatofibroma.
Assuntos
Histiocitoma Fibroso Benigno/diagnóstico , Neoplasias Cutâneas/diagnóstico , Pele/patologia , Adolescente , Adulto , Idoso , Criança , Diagnóstico Diferencial , Feminino , Histiocitoma Fibroso Benigno/classificação , Histiocitoma Fibroso Benigno/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Neoplasias Cutâneas/classificação , Neoplasias Cutâneas/epidemiologia , Adulto JovemRESUMO
Dermatoscopy is a cheap and non-invasive diagnostic technique that improves the diagnostic accuracy of non-pigmented benign and malignant skin tumors. Dermatologist should be aware of dermatoscopic features of non-melanocytic skin tumors to reach the correct diagnosis.
Assuntos
Dermoscopia/métodos , Neoplasias Cutâneas/diagnóstico , Acantoma/diagnóstico , Biópsia por Agulha , Carcinoma Basocelular/diagnóstico , Carcinoma de Células Escamosas/diagnóstico , Dermatologia/instrumentação , Diagnóstico Diferencial , Feminino , Histiocitoma Fibroso Benigno/diagnóstico , Humanos , Imuno-Histoquímica , Ceratose Actínica/diagnóstico , Masculino , Melanócitos/patologia , Nevo Pigmentado/diagnóstico , Sensibilidade e Especificidade , Neoplasias Cutâneas/patologiaRESUMO
An apparently healthy male aged 18 years presented with four subcutaneous swellings. He had no history of leprosy and he did not receive any treatment for leprosy. Histological examination of one of the swellings revealed leprous histiocytoma. The histological features of the lesion have been discussed and available literature reviewed.