RESUMO
Dietary zinc deficiency is widespread in developing countries and is often aggravated by intercurrent acute and chronic infections. Recent studies have demonstrated that zinc supplementation can significantly reduce the morbidity and mortality of apparently well-nourished children and shorten the time to recovery from acute infectious diseases. This review summarises current knowledge of the role of zinc in childhood diarrhoea, acute respiratory infections and malaria, and its potential role in diseases associated with impaired cellular immunity, namely tuberculosis, lepromatous leprosy and leishmaniasis, and explores avenues for future research.
Assuntos
Doenças Transmissíveis/etiologia , Zinco/deficiência , Doença Aguda , Adulto , Criança , Doenças Transmissíveis/terapia , Países em Desenvolvimento , Diarreia/etiologia , Suplementos Nutricionais/efeitos adversos , Humanos , Imunidade Celular , Leishmaniose/etiologia , Hanseníase Virchowiana/etiologia , Malária/etiologia , Infecções Respiratórias/etiologia , Tuberculose/etiologia , Zinco/administração & dosagem , Zinco/intoxicaçãoRESUMO
The case of a 40 years male suffering from post-kala-azar dermal leishmaniasis simulating nodular lepromatous leprosy is reported. In countries where leprosy is endemic, other diseases are not infrequently taken to be leprosy (Schaller, 1971). Dermal leishmaniasis is a common cause of confusion in countries where the condition is endemic (Browne, 1964). Dharmendra and Chatterji (1940) discussed in detail the question of differential diagnosis between Leprosy and Dermal Leishmaniasis. The present communication is concerned with a patient suffering from post-kala-azar dermal leishmaniasis whose skin lesions simulated nodular lepromatous leprosy.