Assuntos
Linfoma Anaplásico de Células Grandes , Neoplasias Cutâneas , Humanos , Linfoma Anaplásico de Células Grandes/complicações , Linfoma Anaplásico de Células Grandes/diagnóstico , Omento/patologia , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologiaRESUMO
Primary cutaneous anaplastic large cell lymphoma is a kind of cluster of differentiation 30+ primary cutaneous lymphoproliferative disorders with a relatively good prognosis in the absence of high-stage disease. Primary cutaneous anaplastic large cell lymphoma shows a higher frequency in males and commonly affects the head and neck. Palpebral involvement is very rare. We present a 42-year-old lady patient with primary cutaneous anaplastic large cell lymphoma involving the eyelid which was initially misdiagnosed as stye. The patient underwent a total excision of the lesion and showed complete regression of the lesion after surgery without any other treatment. There was no evidence of local or systemic disease during follow-up after nine months.
Assuntos
Linfoma Anaplásico de Células Grandes , Linfoma Anaplásico Cutâneo Primário de Células Grandes , Dermatopatias , Neoplasias Cutâneas , Adulto , Pálpebras/patologia , Pálpebras/cirurgia , Feminino , Humanos , Linfoma Anaplásico de Células Grandes/diagnóstico , Linfoma Anaplásico Cutâneo Primário de Células Grandes/diagnóstico , Linfoma Anaplásico Cutâneo Primário de Células Grandes/patologia , Masculino , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgiaAssuntos
Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Hiperpigmentação/diagnóstico por imagem , Hiperpigmentação/etiologia , Linfoma Anaplásico de Células Grandes/complicações , Linfoma Anaplásico de Células Grandes/diagnóstico por imagem , Adulto , Diagnóstico Diferencial , Humanos , Hiperpigmentação/tratamento farmacológico , Linfoma Anaplásico de Células Grandes/tratamento farmacológico , MasculinoRESUMO
Non-Hodgkin lymphoma is a common childhood T-cell and B-cell neoplasm that originates primarily from lymphoid tissue. Cutaneous involvement can be in the form of a primary extranodal lymphoma, or secondary to metastasis from a non-cutaneous location. The latter is uncommon, and isolated cutaneous involvement is rarely reported. We report a case of isolated secondary cutaneous involvement from nodal anaplastic large cell lymphoma (CD30 + and ALK +) in a 7-year-old boy who was on chemotherapy. This case is reported for its unusual clinical presentation as an acute febrile, generalized papulonodular eruption that mimicked deep fungal infection, with the absence of other foci of systemic metastasis.
Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Linfoma Anaplásico de Células Grandes/tratamento farmacológico , Linfoma Anaplásico de Células Grandes/patologia , Neoplasias Cutâneas/tratamento farmacológico , Neoplasias Cutâneas/secundário , Criança , Ciclofosfamida/administração & dosagem , Epirubicina/administração & dosagem , Epirubicina/análogos & derivados , Seguimentos , Humanos , Masculino , Invasividade Neoplásica , Estadiamento de Neoplasias , Prednisolona/administração & dosagem , Doenças Raras , Medição de Risco , Neoplasias Cutâneas/patologia , Resultado do Tratamento , Vincristina/administração & dosagemAssuntos
Linfoma Anaplásico de Células Grandes/diagnóstico , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/secundário , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Ciclofosfamida/uso terapêutico , Doxorrubicina/uso terapêutico , Feminino , Humanos , Linfoma Anaplásico de Células Grandes/tratamento farmacológico , Prednisona/uso terapêutico , Neoplasias Cutâneas/tratamento farmacológico , Vincristina/uso terapêuticoRESUMO
Lepromatous leprosy (LL) has been reported in the literature with Non Hodgkin Lymphoma and rarely with Hodgkin Lymphoma. However, an extensive search of the literature shows no case report describing anaplastic large cell lymphoma (ALCL) in association with LL. We report a case of a young male with LL who was found to have ALCL. This is an interesting case of coexistence of an endemic infectious disease and a rare lymphoma involving the same lymph node, with a brief review of the literature.
Assuntos
Hanseníase Virchowiana/complicações , Linfonodos/patologia , Linfoma Anaplásico de Células Grandes/complicações , Adulto , Forma do Núcleo Celular , Clofazimina/administração & dosagem , Clofazimina/uso terapêutico , Histiócitos/química , Histiócitos/patologia , Humanos , Imuno-Histoquímica , Antígeno Ki-1/química , Hanseníase Virchowiana/tratamento farmacológico , Linfoma Anaplásico de Células Grandes/tratamento farmacológico , Linfoma Anaplásico de Células Grandes/microbiologia , Masculino , Mycobacterium leprae/isolamento & purificação , Mycobacterium leprae/patogenicidade , Pancitopenia/tratamento farmacológico , Pancitopenia/patologia , Rifampina/administração & dosagem , Rifampina/uso terapêutico , Dermatopatias Bacterianas/microbiologia , Dermatopatias Bacterianas/patologiaRESUMO
Anaplastic large cell cutaneous lymphomas are clinically and pathologically heterogeneous, CD30 + (Ki-1) lymphoproliferative disorders. The importance of anaplastic lymphoma kinase (ALK) positivity is well known in the prognosis of primary systemic anaplastic large cell cutaneous lymphomas; however, the same in primary cutaneous anaplastic large cell cutaneous lymphomas is not much clear. Herein we report a 65-year-old male with an 18-month history of minimally pruritic localized nodulo-plaque lesion over lower back. Histology revealed cutaneous large cell lymphoma and immunohistochemical staining showed positivity for CD30, CD3 and ALK. The role of ALK positivity in pcALCL is discussed in this article.