RESUMO
Scalp mucormycosis in children is extremely rare. We present a case of pediatric scalp mucormycosis caused by Rhizopus oryzae in a 9-year-old diabetic girl who was successfully diagnosed and treated with amphotericin B deoxycholate and wound debridement. At 3 months follow up, the patient was stable although she had lost her vision.
Assuntos
Dermatomicoses/diagnóstico , Diabetes Mellitus Tipo 1/diagnóstico , Pálpebras/patologia , Mucormicose/diagnóstico , Couro Cabeludo/patologia , Criança , Dermatomicoses/complicações , Diabetes Mellitus Tipo 1/complicações , Diabetes Mellitus Tipo 1/terapia , Pálpebras/microbiologia , Feminino , Seguimentos , Humanos , Mucormicose/complicações , Mucormicose/terapia , Rhizopus/isolamento & purificação , Couro Cabeludo/microbiologia , Transtornos da Visão/diagnóstico , Transtornos da Visão/etiologiaRESUMO
A 53 year-old male diabetic presented with a month-old, painful ulcer with necrotic margins over the right thigh. Wound debridement was done twice and the ulcer showed recurrent growth of a white, cottony filamentous structure. Cutaneous mucormycosis was suspected and confirmed by histopathology and a culture isolate of Apophysomyces elegans . The patient was treated with liposomal amphotericin-B and itraconazole followed by partial thickness skin grafting, and then discharged after being prescribed posaconazole syrup for three weeks. Regular follow-up was done and during the last visit after six months following discharge, the ulcer was found to have healed well with no recurrence of the fungus.
Assuntos
Dermatomicoses/microbiologia , Mucormicose/microbiologia , Acidentes de Trânsito , Antifúngicos/uso terapêutico , Desbridamento , Dermatomicoses/etiologia , Dermatomicoses/terapia , Complicações do Diabetes , Quimioterapia Combinada , Humanos , Masculino , Pessoa de Meia-Idade , Mucorales/isolamento & purificação , Mucormicose/etiologia , Mucormicose/terapia , Recidiva , Pele/microbiologia , Transplante de Pele , Coxa da PernaRESUMO
The term mucormycosis encompasses a distinctive group of infections caused by fungi belonging to genera within the taxonomic order Mucorales, usually Rhizopus, Absidia, Mortierella, and Mucor. These fungi are widespread in nature, subsisting on decaying vegetation and diverse organic materials. Although the fungi and spores of Mucorales show minimal intrinsic pathogenicity toward normal persons, they can initiate aggressive and fulminant infections under certain clinical conditions. Ketoacidotic diabetics are predisposed to rhinocerebral mucormycosis, whereas patients with leukemia or lymphoma are susceptible to pulmonary or disseminated infections. These infections, which often result in devastating long-diagnostic and therapeutic challanges