Assuntos
Carcinossarcoma/secundário , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/cirurgia , Neoplasias Cutâneas/secundário , Neoplasias Cutâneas/cirurgia , Idoso de 80 Anos ou mais , Biópsia por Agulha , Carcinossarcoma/patologia , Carcinossarcoma/cirurgia , Humanos , Imuno-Histoquímica , Japão , Masculino , Prognóstico , Doenças Raras , Neoplasias Cutâneas/patologia , Cirurgia Torácica Vídeoassistida/métodos , Resultado do TratamentoAssuntos
Neoplasias Faciais/patologia , Neoplasias Cutâneas/patologia , Carcinoma de Células Escamosas de Cabeça e Pescoço/patologia , Neoplasias da Língua/patologia , Bochecha , Neoplasias Faciais/secundário , Humanos , Ceratoacantoma/patologia , Masculino , Pessoa de Meia-Idade , Pescoço , Neoplasias Cutâneas/secundário , Carcinoma de Células Escamosas de Cabeça e Pescoço/secundário , Carcinoma de Células Escamosas de Cabeça e Pescoço/terapia , Neoplasias da Língua/terapiaAssuntos
Neoplasias do Colo/diagnóstico , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/secundário , Idoso , Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Neoplasias do Colo/tratamento farmacológico , Feminino , Humanos , Neoplasias Cutâneas/tratamento farmacológicoRESUMO
BACKGROUND: A wide variety of systemic diseases and internal malignancies have cutaneous manifestations. In the context of internal malignancy, many cutaneous changes are highly specific to the underlying malignancy, while other changes are nonspecific. Some changes are also due to the modalities employed in the treatment of malignancies. METHODS: Two hundred and fifty patients who were diagnosed with internal malignancy and who were attending the department of radiation oncology, were evaluated at the Department of Dermatology, Sexually Transmitted Diseases and Leprosy of Government Medical College, Srinagar. The study was conducted over a period of 5 months. Relevant investigations, wherever needed, were carried out. RESULTS: Among the 250 cases examined, nonspecific cutaneous changes were seen in 39 (15.6%) cases, whereas specific skin lesions in the form of cutaneous metastases were seen in two (0.8%) patients. Nail changes and hair changes were also seen in some patients. LIMITATIONS: As this was a cross-sectional study and most of the patients were lost to follow up, we could not assess the outcome of the dermatological changes seen in the affected patients. CONCLUSION: Many dermatological changes are noticed early in the course of malignancy, reflecting a strong association of the cutaneous change with malignancy. Few manifestations occur late in the course of the disease, indicating dissemination or immunosuppression. Some changes reflect radiation-induced or chemotherapy-induced toxicity, indicating the need for treatment modifications.
Assuntos
Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/epidemiologia , Centros de Atenção Terciária/tendências , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias/diagnóstico , Neoplasias/epidemiologia , Neoplasias Cutâneas/secundário , Adulto JovemRESUMO
Non-Hodgkin lymphoma is a common childhood T-cell and B-cell neoplasm that originates primarily from lymphoid tissue. Cutaneous involvement can be in the form of a primary extranodal lymphoma, or secondary to metastasis from a non-cutaneous location. The latter is uncommon, and isolated cutaneous involvement is rarely reported. We report a case of isolated secondary cutaneous involvement from nodal anaplastic large cell lymphoma (CD30 + and ALK +) in a 7-year-old boy who was on chemotherapy. This case is reported for its unusual clinical presentation as an acute febrile, generalized papulonodular eruption that mimicked deep fungal infection, with the absence of other foci of systemic metastasis.