Assuntos
Epididimite/microbiologia , Eritema Nodoso/microbiologia , Hanseníase Tuberculoide/diagnóstico , Mycobacterium leprae/isolamento & purificação , Orquite/microbiologia , Adulto , Biópsia por Agulha , Quimioterapia Combinada , Epididimite/complicações , Epididimite/tratamento farmacológico , Epididimite/patologia , Eritema Nodoso/complicações , Eritema Nodoso/tratamento farmacológico , Eritema Nodoso/patologia , Seguimentos , Humanos , Índia , Hanseníase Tuberculoide/complicações , Hanseníase Tuberculoide/tratamento farmacológico , Masculino , Orquite/complicações , Orquite/tratamento farmacológico , Orquite/patologia , Medição de Risco , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
Twenty five patients of lepromatous leprosy were studied clinically and histopathologically for testicular involvement. Testicular pain or swelling was the commonest complaint (68%) followed by sterility (28%) and impotence (4%). Reduced testicular size associated with soft feel was observed in 76% patients. Gynaecomastia was present in 36% and altered sexual hair pattern in 24%. Eleven out of sixteen (69%) patients had oligo/azoospermia. Out of the twenty testicular biopsies 15 (75%) had definite histological evidence of leprous pathology, irrespective of testicular size, semen picture and clinical signs and symptoms. One out of three epididymal biopsies showed minimal changes. Histopathological changes varied markedly, it was not possible to categorize these into vascular, interstitial and obliterative phases.
Assuntos
Hanseníase/patologia , Orquite/patologia , Testículo/patologia , Adolescente , Adulto , Idoso , Atrofia , Humanos , Hanseníase/complicações , Hanseníase/imunologia , Células Intersticiais do Testículo/patologia , Masculino , Pessoa de Meia-Idade , Orquite/etiologia , Orquite/imunologia , Túbulos Seminíferos/patologiaAssuntos
Epididimite/patologia , Doenças dos Genitais Masculinos/patologia , Orquite/patologia , Escroto/patologia , Adulto , Criança , Granuloma/patologia , Humanos , Hipersensibilidade/patologia , Hanseníase/patologia , Masculino , Microscopia Eletrônica , Pessoa de Meia-Idade , Infecções Sexualmente Transmissíveis/patologia , Testículo/ultraestrutura , Tuberculose dos Genitais Masculinos/patologia , Viroses/patologiaRESUMO
Twenty five patients of lepromatous leprosy were studied clinically and histopathologically for testicular involvement. Testicular pain or swelling was the commonest complaint (68%) followed by sterility (28%) and impotence (4%). Reduced testicular size associated with soft feel was observed in 76% patients. Gynaecomastia was present in 36% and altered sexual hair pattern in 24%. Eleven out of sixteen (69%) patients had oligo/azoospermia. Out of the twenty testicular biopsies 15 (75%) had definite histological evidence of leprous pathology, irrespective of testicular size, semen picture and clinical signs and symptoms. One out of three epididymal biopsies showed minimal changes. Histopathological changes varied markedly, it was not possible to categorize these into vascular, interstitial and obliterative phases.
Assuntos
Masculino , Humanos , Adulto , Pessoa de Meia-Idade , Idoso , Adolescente , Atrofia , Células Intersticiais do Testículo/patologia , Hanseníase/complicações , Hanseníase/imunologia , Hanseníase/patologia , Orquite/etiologia , Orquite/imunologia , Orquite/patologia , Testículo/patologia , Túbulos Seminíferos/patologiaRESUMO
Two patients with lepromatous leprosy presenting initially because of lepromatous orchitis are reported. These cases are unusual because they were diagnosed as lepromatous orchitis at a stage when no other evidence of leprosy was present. Generalized skin lesions characteristic of lepromatous leprosy subsequently developed in one of these patients. It is suggested that lepromatous orchitis should be actively considered in the differential diagnosis of orchitis and infertility.