Assuntos
Síndrome da Imunodeficiência Adquirida/complicações , Dermatoses Faciais/diagnóstico , Lúpus Eritematoso Sistêmico/diagnóstico , Pelagra/diagnóstico , Tinha/diagnóstico , Adulto , Dorso , Diagnóstico Diferencial , Dermatoses Faciais/microbiologia , Feminino , Humanos , Pessoa de Meia-Idade , Pescoço , Tinha/complicaçõesRESUMO
Pellagra is a niacin deficiency disorder characterized clinically by diarrhea, dermatitis, and dementia. However, few drugs also cause pellagroid dermatitis. Recently, we encountered two cases of pellagroid dermatitis; both were on second line of antituberculosis drugs. Case 1 was of multidrug-resistant pulmonary tuberculosis. Patient was on ethionamide since one year before developing pellagroid dermatitis. Case 2 was of central nervous system tuberculoma and was on second line of antitubercular drugs. This patient was on ethionamide and isoniazid (INH) since six months before developing pellagroid dermatitis. This patient had previously taken first line of antituberculous therapy, inclusive of INH, for 1 year without any dermatitis. The skin lesions in both patients were symmetric hyperpigmented thickened plaques with prominent skin markings resembling lichen simplex chronicus. Nicotinamide 300 mg in three divided doses healed the lesions completely within 4 weeks and 3 weeks in first and second patient, respectively.
Assuntos
Dermatite/diagnóstico , Etionamida/efeitos adversos , Neurodermatite/induzido quimicamente , Neurodermatite/diagnóstico , Pelagra/induzido quimicamente , Pelagra/diagnóstico , Adulto , Diagnóstico Diferencial , Feminino , Humanos , Adulto JovemRESUMO
La Pelagra es una patología conocida como la enfermedad de las tres D: dermatitis, diarrea y demencia, provocada por la deficiencia de niacina, una vitamina del complejo B. Hoy sabemos que la pelagra es un desorden nutricional producido por déficit en niacina, también llamada ácido nicotínico. Los autores diagnosticados dos pacientes que ingresaron en el Hospital Provincial de Malange, Angola; por un cuadro diarreico con edema de manos y pies y lesiones de piel consistentes en eritema vesículas escama y pigmentación en área del cuellos, miembros superiores e inferiores, además de retraso en el desarrollo pondoestatural (AU)
The Pellagra is well-known as the illness of the three D; dermatitis, diarrhea and Insanity, due to the niacina deficiency, a B-complex vitamin. Today we know that the pellagra is a nutritional disorder taken place by deficit in niacin, also call nicotinic acid. The authors diagnosed two patients with a diarrhea, edema of hands and feet and consistent skin lesion in erythema vesicles flake and pigmentation in area of the neck superior members and inferior members (AU)