1.
Patol Fiziol Eksp Ter
; (2): 18-20, 2004.
Artigo
em Russo
| MEDLINE
| ID: mdl-15208923
RESUMO
Mice experiments were made to study effects of diaminodiphenylsulphone (DDS)--basic antileprous drug--on circadian rhythms of hemoglobin levels, counts of red cells and leukocytes. The time of the drug administration varied within the day while seasons of the year were two--winter and summer. Blood components were studied with unified methods. The results of the study showed that DDS has significant effects on the structure of circadian rhythms of the above blood components. These effects correlate with the season of the year and time of DDS administration.
Assuntos
Sangue/efeitos dos fármacos , Dapsona/farmacologia , Hansenostáticos/farmacologia , Estações do Ano , Animais , Fenômenos Cronobiológicos , Ritmo Circadiano/efeitos dos fármacos , Dapsona/administração & dosagem , Contagem de Eritrócitos , Feminino , Hemoglobinas/efeitos dos fármacos , Contagem de Leucócitos , Masculino , Camundongos , Camundongos Endogâmicos CBA
2.
Biull Eksp Biol Med
; 123(4): 455-9, 1997 Apr.
Artigo
em Russo
| MEDLINE
| ID: mdl-9190194