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1.
Stat Med ; 19(17-18): 2309-20, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-10960855

RESUMO

Maps of disease rates (and other quantities) often must contend with variance associated with variable population sizes and low incidence within spatial units. These characteristics can lead to substantial statistical noise that can mask underlying spatial variation. As Gelman and Price illustrated, most conventional mapping methods fail to address this problem, and in fact can introduce statistical artefacts; mapped quantities can show spatial patterns even when there are no spatial patterns in the underlying parameter of interest. Kafadar evaluated the performance of the headbanging algorithm for spatial smoothing (Tukey and Tukey, Hansen) for eliminating small scale variation and preserving edge structure. Here we perform a simulation study to investigate the artefacts of maps smoothed by unweighted and weighted headbanging. We find substantial artefacts that depend on the spatial structure of the statistical variation (for example, the spatial pattern of sample sizes) and on the details of the spatial distribution of geographic units. The methods used here could readily be adapted to study other spatial smoothers; we choose headbanging because (i) it is an important method used in practice, and (ii) its heavily computational nature is naturally studied using simulation (in contrast to the analytical methods used by Gelman and Price).


Assuntos
Métodos Epidemiológicos , Modelos Estatísticos , Artefatos , Teorema de Bayes , Humanos , Mapas como Assunto , Tennessee/epidemiologia
2.
South Med J ; 77(8): 995-7, 1000, 1984 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-6463701

RESUMO

Three diseases representative of specific health conditions affecting the Southeast Asian refugees living in middle Tennessee are leprosy (chronic bacterial infections), liver fluke infection (parasitic diseases), and hemoglobin E-beta-thalassemia (hematologic disorders). In this paper we discuss incidence, causative agent, mode of transmission, metabolic abnormalities, and management of these conditions.


Assuntos
Doenças Hematológicas/diagnóstico , Enteropatias Parasitárias/diagnóstico , Hanseníase/diagnóstico , Refugiados , Sudeste Asiático/etnologia , Dapsona/uso terapêutico , Quimioterapia Combinada , Feminino , Doenças Hematológicas/complicações , Hemoglobina E , Humanos , Recém-Nascido , Enteropatias Parasitárias/tratamento farmacológico , Laos/etnologia , Hanseníase/tratamento farmacológico , Masculino , Mebendazol/administração & dosagem , Pessoa de Meia-Idade , Niclosamida/administração & dosagem , Gravidez , Complicações Infecciosas na Gravidez/parasitologia , Esplenectomia , Tennessee , Talassemia/complicações , Talassemia/diagnóstico , Tuberculose Cutânea/diagnóstico , Tuberculose Cutânea/tratamento farmacológico
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