The early cellular response to M. leprae
s.l; s.n; jul. 1978. 13 p.
Não convencional
em Inglês
| SES-SP, HANSEN, HANSENIASE, SESSP-ILSLACERVO, SES-SP
| ID: biblio-1240389
Biblioteca responsável:
BR191.1
Localização: [{"text": "BR191.1", "_a": "02143/s"}]
ABSTRACT
The ultrastructural changes that develop in mouse peritoneal macrophages from 10 minutes up to 14 weeks after exposure to Mycobacterium leprae are presented. Phagocytosis occurred by a process of engulfment by cytoplasmic processes and incorporation into a phagosome, into which lysosomal enzymes were subsequently introduced. Electron transparent zones (E.T.Z.) were not observed around phagocytosed bacilli in this study, however discrete droplets of lipid-like material appeared in the cytoplasm of macrophages, between 2 and 4 weeks after ingestion of the micro-organisms. Phagosomes with double limiting membranes were observed in macrophages harvested as early as 40 minutes after exposure to M. leprae, contrary to the observations of Evans and Levy (1972).
Tema:
Complicações
/
Geral
Bases de dados:
HANSEN
/
HANSENIASE
/
Sec. Est. Saúde SP
Assunto principal:
Fagocitose
/
Fatores de Tempo
/
Hanseníase
/
Macrófagos
/
Camundongos Endogâmicos CBA
/
Mycobacterium leprae
Idioma:
Inglês
Ano de publicação:
1978
Tipo de documento:
Não convencional
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