Sodium hydnocarpate in leprosy, suggested improvements in administration

ABSTRACT

1) While the intravenous injection of sodium hydnocarpate may be admitted as the most effective means of administering hydnocarpus preparations, the blocking of veins has hitherto interfered with prolonged administration in this way.2) The sodium salts derived from a special fraction of H. wightiana and also the sodium salts of H. anthelmintica and alpina block the veins less than the salts from the whole H. wightiana oil.3) A new method of mixing the salts prepared from the whole oil of H. wightiana with blood before injection has received vein-blocking to a much more marked extent.4) Alternation of intravenous sodium hydnocarpate with subcutaneous infiltration of hydnocarpus oil with creosote is advised chiefly because of the haemolytic effect of the former preparations.