Dapsone-induced haemolytic anaemia, hepatitis and agranulocytosis in a leprosy patient with normal glucose-6-phosphate-dehydrogenase activity.
Lepr Rev
; 79(4): 436-40, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-19274991
ABSTRACT
A 21 year old boy with borderline lepromatous leprosy and normal glucose-6-phosphate-dehydrogenase activity developed haemolytic anaemia, hepatitis and agranulocytosis following 19 weeks of multi-bacillary multi-drug therapy. With early administration of antibiotics and G-CSF our patient recovered without residual complications. All patients taking dapsone should be warned to discontinue the drug immediately in the event of fever, chills and sore throat occurring within the treatment period until further investigations are performed.
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Tema:
Complicacoes
/
Geral
/
Tratamento_medicamentoso
Bases de dados:
MEDLINE
Assunto principal:
Dapsona
/
Agranulocitose
/
Anemia Hemolítica
/
Hansenostáticos
/
Hanseníase
Idioma:
En
Revista:
Lepr Rev
Ano de publicação:
2008
Tipo de documento:
Article