Case Report: Molecular Confirmation of Lobomycosis in an Italian Traveler Acquired in the Amazon Region of Venezuela.
Am J Trop Med Hyg
; 97(6): 1757-1760, 2017 Dec.
Article
em En
| MEDLINE
| ID: mdl-29016315
ABSTRACT
Lobomycosis is a chronic skin mycosis endemic in Amazon regions characterized by chronic nodular or keloidal lesions caused by Lacazia loboi, an uncultivable fungus. Imported cases in nonendemic countries are rare and diagnosed after years. We describe a case of lobomycosis in a healthy 55-year-old Italian traveler who had acquired the infection during 5-day-honeymoon in the Amazon region of Venezuela in 1999. Several weeks after return, he recalled pruritus and papular skin lesions on the left lower limb, subsequently evolving to a plaque-like lesion. Blastomycosis and cryptococcosis were hypothesized based on microscopic morphology of yeast-like bodies found in three consecutive biopsies, although fungal cultures were always negative. In 2016, exfoliative cytology and a biopsy specimen examination showed round yeast-like organisms (6-12 µm), isolated or in a chain, connected by short tubular projections fulfilling the morphologic diagnostic criteria of Lacazia spp. The microscopic diagnosis was confirmed by molecular identification.
Texto completo:
1
Tema:
Geral
/
Tratamento_medicamentoso
Bases de dados:
MEDLINE
Assunto principal:
Lacazia
/
Lobomicose
Tipo de estudo:
Prognostic_studies
País/Região como assunto:
America do sul
/
Europa
/
Venezuela
Idioma:
En
Revista:
Am J Trop Med Hyg
Ano de publicação:
2017
Tipo de documento:
Article