Case Report: Borderline Lepromatous Leprosy Therapy Complicated by Type 1 Leprosy Reaction and Adverse Reactions with Dapsone and Clofazimine.
Am J Trop Med Hyg
; 110(3): 483-486, 2024 Mar 06.
Article
em En
| MEDLINE
| ID: mdl-38266303
ABSTRACT
Leprosy is a global health issue, causing long-term functional morbidity and stigma. Rapid diagnosis and appropriate treatment are important; however, early diagnosis is often challenging, especially in nonendemic areas. Here, we report a case of borderline lepromatous leprosy accompanied by dapsone-induced (neutropenia, anemia, and methemoglobinemia) and clofazimine-induced (skin discoloration and ichthyosis) side effects and type 1 leprosy reactions during administration of the multidrug therapy. The patient completely recovered without developing any deformities or visual impairment. To ensure early diagnosis and a favorable outcome, clinicians should be aware of the diminished sensation of skin lesions as a key physical finding and manage the drug toxicities and leprosy reactions appropriately in patients on multidrug therapy.
Texto completo:
1
Tema:
Complicacoes
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Geral
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Prevencao_controle
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Tratamento_medicamentoso
Bases de dados:
MEDLINE
Assunto principal:
Hanseníase Dimorfa
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Hanseníase Virchowiana
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Dermatopatias Bacterianas
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Doenças do Sistema Nervoso Periférico
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Hanseníase Multibacilar
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Hipersensibilidade
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Hanseníase
Tipo de estudo:
Screening_studies
Idioma:
En
Revista:
Am J Trop Med Hyg
Ano de publicação:
2024
Tipo de documento:
Article