Is metabolic dysregulation associated with antidepressant response in depressed women in climacteric treated with individualized homeopathic medicines or fluoxetine? The HOMDEP-MENOP Study.

BACKGROUND: Climacteric is associated with both depression and metabolic dysregulation. Scarce evidence suggests that metabolic dysregulation may predict poor response to conventional antidepressants. Response to depression treatment has not been studied in homeopathic medicine. The aim of this study was to investigate the prevalence of metabolic disorders in depressed climacteric women treated with homeopathic medicines, fluoxetine or placebo, and if these alterations have any association with response to depression treatment. METHODS: One hundred and thirty-three Mexican women (40-65 years) with depression, enrolled in the HOMDEP-MENOP study, a randomized, placebo-controlled, double-blind, double-dummy, three-arm trial with a 6 week follow-up, underwent a complete medical history and clinical examination. Metabolic parameters were assessed at baseline. Association between baseline metabolic parameters and response to depression treatment was analyzed with bivariate analysis in the three groups. Odds ratios (OR) with their 95% confidence interval (95% CI) were calculated. Metabolic parameters were considered for inclusion in the logistic regression model if they had a statistically significant relationship with response rate on bivariate analysis at p<0.05 or if they were clinically relevant. RESULTS: Overall combined prevalence (obesity and overweight) was 86.5%; 52.3% had hypertriglyceridemia; 44.7% hypercholesterolemia; 46.7% insulin resistance; and 16% subclinical hypothyroidism. There was no statistically significant association between dyslipidemia, overweight, or insulin resistance and non-response in the homeopathy group [OR (95% CI) 1.57 (0.46-5.32), p=0.467; 0.37 (0.003-1.11), p=0.059; 0.67 (0.16-2.7), p=0.579, respectively]. CONCLUSION: Metabolic dysregulation was not significantly associated with response to depression treatment in depressed climacteric women treated with individualized homeopathic treatment (IHT), fluoxetine or placebo. Due to the high prevalence of metabolic disorders and its relationship with depression in the climacteric, further investigation should be focused on whether individualized prescriptions based on classical homeopathy for depressed climacteric women have an effect on metabolic parameters, and/or if treating the metabolic disorders at the same time could lead to higher response rates. ClinicalTrials.gov Identifier: NCT01635218 URL: http://clinicaltrials.gov/ct2/show/NCT01635218?term=depression+homeopathy&rank=1.

Effective Treatment of Diabetes Mellitus by Resonance Medicine.

The metabolic disorder known as diabetes mellitus (DM) has several different causes, distinguished by recurring hyperglycemia due to inadequate insulin secretion, insulin action, or both. T-lymphocytes target such cells for destruction, which include beta cells. Transplants of the pancreas, islets of Langerhans, and individual beta cells are all effective treatments for DM. Additionally, treating DM using stem cells is popular currently. The basis of stem cell therapy for DM is the replacement of beta cells, or dead pancreatic cells, with stem cells. After attaching to the tissues of the pancreas, the stem cells differentiate into active cells. An X-ray scanner is used to place a catheter into the pancreatic artery in DM, and the process lasts 90 minutes. The use of stem cells to replace dead pancreatic beta cells forms the cornerstone of stem cell treatment for DM. Transplants of the pancreas, islets of Langerhans, and individual beta cells are all effective treatments for insulin-dependent DM. In contrast to prior studies, where we only used low potencies of nosodes and organopreparations, our research used both high and low potencies of these substances. Choosing the strength of the nosode stomach cancer in the computer-connected device selector so that it will resonate with the nosode that is tested in the patient's device is the doctor's responsibility when using the bioresonance therapy method. The initial nosode, which is in the computer programme of the device for bioresonance therapy, is no longer tested when the stomach cancer nosode is tested in a patient along with the chosen potency of this nosode. The initial nosode in the bioresonance therapy device itself is still being studied in case the chosen nosode's potency is inadequate (the frequency of oscillations of the nosode is lower than the frequency of oscillations of the tumour).

Hyperoxalosis Secondary to Intravenous Vitamin C Administration as a Non-Allopathic Treatment for Cancer.

Vitamin C (ascorbic acid) has long been known to have antioxidant properties, with associated claims that it can boost the immune system, fight off infection, and help in the treatment of cancer. Similar to many other over-the-counter and herbal medicines, vitamin C can cause potential side effects with significant morbidity and rarely mortality. We discuss a case of an elderly woman with metastatic adenocarcinoma of the lung that was treated with several rounds of allopathic chemotherapy; however, treatment was stopped because of worsening quality of life and disease progression. She was treated with 10 courses of intravenous high-dose vitamin C at a local homeopathic medical center as an alternative treatment method. Five days after the last vitamin C administration, she was admitted to an allopathic hospital due to acute renal failure and oliguria culminating in a myocardial infarct due to underlying atherosclerotic disease. Workup revealed dehydration secondary to poor oral intake and acute renal failure which was clinically concerning for calcium oxalate- induced kidney injury. At the time of autopsy, in addition to her widely metastatic adenocarcinoma and myocardial damage, hyperoxalosis of the kidney with acute kidney injury was present. Hyperoxalosis of the kidney is a documented phenomenon related to administration of intravenous and oral vitamin C at superphysiologic doses as recommended by some natural and homeopathic practitioners and is, therefore, a significant complication of treatment. This case highlights the renal complications of supertherapeutic vitamin C administration and the associated morbidity which can contribute to death.

Homeopathic treatment for prolonged postoperative coma: a case report.

Coma is the state of unrousable unconsciousness. There are variations in the degree of coma and the findings and signs found on the patient's clinical examination depend on the underlying cause of the disorder. The Glasgow Coma scale evaluates the best motor, verbal and eye answers of the patient. A patient is considered to be in a coma if his Glasgow Coma Scale is below 8 points. The progress that we have made throughout the years has also led to complications that can culminate in a major catastrophe like death, permanent brain damage, coma. A study performed reached the conclusion that prior comorbidity, older age, intraoperative hypotension, and cardiovascular surgery may predispose patients to postoperative coma. The article presents a case of postoperative coma treated successfully with homeopathy. Although a rare complication, postoperative coma is a severe, death-leading condition, causing immense suffering on both the patient and the patient's family. A multidisciplinary and thorough approach is necessary for these patients, but even after a well-conducted therapy, this condition leads to the death of the patient.

Observations on 73 Vaccine breakthrough COVID-19 infected patients and its individualized homeopathic treatment

Since the initiation of vaccine rollout, breakthrough COVID-19 infections have been reported. While conventional therapy is the accepted mode of treatment, there has been little recognition of the role played by the alternative therapies like homeopathy. The purposes of this study were to identify the clinico-symptomatic profile of the vaccine breakthrough covid-19 infections and to assess the response of individualized homoeopathic treatment in these breakthrough cases. A retrospective data analysis of patients treated with homoeopathic medicines who confirmed the breakthrough infection criteria: positive infection ≥14 days after completion of both the recommended doses of an authorized COVID-19 vaccine was conducted. IBM SPSS Statistics 21.0 was used for data analysis with a p-value below 0.05 defined as significant. WHO Clinical Progression Scale and Outcome in Relation to Impact on Daily Living score were used as outcome measures. In total 73 cases were reported to be vaccine breakthrough infections. The median recovery time reported in the data set was 9 ± 2 days. While 5 patients dropped out, 68 (93.15%) patients responded positively to homeopathic treatment, and 55 (75.34%) recovered completely with normalized serological markers/ nasal swabs/ HRCT Chest. About 29 (39.72%) of these presented with mild clinical manifestations, 26 (35.61%) moderate, 17 (23.28%) severe and 1 (1.36%) was critical. 10 homeopathic remedies were prescribed to these 73 patients. Majority of the patients attained an ORIDL score of 4. Maximum patients reported a WHO clinical Progression score of 3. Statistical analysis showed a significant response to homeopathic treatment in the study group. Vaccine breakthrough cases occur in a fraction of vaccinated people. Despite the limited number of study subjects, homoeopathy showed some promising results in the present setup. The response rate was highest in the moderate and severe cases which suggest the importance of consideration of alternative medicine in the current pandemic. Further exploratory research studies and comparative clinical trials may be encouraged.

Uso de complexo homeopático reduz o parasitismo por carrapatos e amplia o intervalo de tempo entre tratamentos com acaricidas / Homeopathic complex decreases tick parasitism and increases the interval between treatments with acaricides

O presente trabalho avaliou a segurança e eficácia de 2 formulações homeopáticas no tratamento populacional de bovinos naturalmente parasitados com carrapatos da espécie Rhipicephalus (Boophilus) microplus. Foram realizados 2 experimentos utilizando complexos homeopáticos distintos, ambos com 20 vacas adultas, raça holandesa, em diferentes estágios de lactação, distribuídas em grupo controle (n= 10) e grupo tratado (n= 10) num estudo randomizado com duplo cego. A contagem de carrapatos foi registrada nos dias 7, 14, 21 e 28 após o tratamento homeopático e, posteriormente, em intervalos de 15 dias até o dia 140 do Experimento 01 e o dia 197 do Experimento 02. A formulação homeopática utilizada no Experimento 01 apresentou eficácia de 21,1%, sendo necessária intervenção com tratamento convencional durante o período de 140 dias. A eficácia do complexo homeopático no Experimento 02 foi de 6,7%. Os resultados foram seguros e eficazes na terapia antiparasitária, tendo bons resultados quando complementados com o uso racional e correto de acaricidas. (AU)

In the present study evaluated the efficacy of 2 homeopathic formulas in the treatment of cattle naturally with Rhipicephalus (Boophilus) microplus ticks. Two experiments were carried out using different combinations of homeopathic medicines, with 20 adult Holstein cows, in different stages of lactation, allocated to the control (n= 10) and treated (n= 10) groups in a randomized double-blind placebo-controlled trial. Tick count was performed on days 7, 14, 21 and 28 after homeopathic treatment ,and then at 15-day intervals up to day 140 in Experiment 1 and day 197 in Experiment 2. Efficacy in Experiment 1 was 21.1%, while conventional intervention was required along the 140-day period. Efficacy in Experiment 2 was 6.7%. The results indicate that the tested homeopathic formulas were safe and efficacious, outcomes being satisfactory when homeopathic treatment was combined with rational and correct conventional treatment. (AU)

Alergias alimentares na infância: uma abordagem homeopática / Food allergies in childhood: a homeopathic approach

As alergias alimentares são condições muito frequentes dentre as queixas pediátricas, sendo a alergia às proteínas do leite de vaca (APLV) o tipo mais comum na infância. Apesar de sua prevalência, há controvérsias na literatura sobre o diagnóstico e o tratamento convencional. A Homeopatia oferece uma opção valiosa para a abordagem dessas patologias, uma vez que age conforme a totalidade sintomática característica de cada caso, isto é, de forma individualizada. O presente relato é sobre uma criança, do sexo masculino, com diagnóstico prévio de APLV, apresentando crises respiratórias frequentes e uso recorrente de antibióticos, além de estar submetido a uma dieta restrita. A mãe buscou tratamento homeopático como alternativa à terapêutica vigente, uma vez que os resultados obtidos até então eram pouco satisfatórios. O caso foi conduzido segundo os preceitos da homeopatia clássica hahnemanniana, com obtenção de um medicamento único segundo o método de repertorização. Optou-se pelo tratamento com o medicamento Lycopodium clavatum, considerado o mais semelhante segundo a individualidade do paciente. A criança foi acompanhada por pouco mais de um ano, observando-se melhora clínica importante da queixa inicial, além de mais qualidade de vida à criança e à família.

Food allergies are very common conditions amongst pediatric complaints, and cow's milk protein allergy (CMPA) is the most common kind in childhood. Despite its prevalence, there are controversies in the literature about diagnosis and conventional treatments. Homeopathy offers a valuable option for approaching these pathologies, since it acts according to the characteristic symptomatic totality of each case, that is, in an individualized way. This report is about a child, male, with a previous diagnosis of CMPA, with frequent respiratory crises and recurrent use of antibiotics, in addition to being submitted to a restricted diet. His mother looked for homeopathic treatment as an alternative to current therapy, since the results obtained so far were unsatisfactory. The case was conducted according to the precepts of classical Hahnemannian homeopathy, obtaining a single medicine according to the repertorization method. We opted for treatment with Lycopodium clavatum, considered the most similar according to the individuality of the patient. The child was followed up for a little over a year, and significant clinical improvement of the initial complaint was observed, in addition to better quality of life for the child and family.

Hemangioma infantil congênito: opção de tratamento homeopático com medicamento calcárea carbônica / Congenital infantile hemangioma: homeopathic treatment option with carbonic limestone medicine

Este é o relato de um caso clínico de uma criança lactente que a desde o nascimento possui uma tumefação de coloração vermelho-rubro na região occipital direita e outra na região infra escapular próxima a axila ipsilateral, de relevo e bordas irregulares. À avaliação médica, ficou com diagnóstico de hemangioma infantil. O hemangioma infantil é um tumor vascular benigno comum, representando a anomalia vascular mais frequentemente encontrada em idade pediátrica. O objetivo deste trabalho foi mostrar a ação do tratamento homeopático com a medicação Calcárea Carbônica como opção terapêutica com boa eficácia para o tratamento do hemangioma infantil.

The present document outlines the clinical case of an infant child who, since birth, has a reddish-red swelling in the right occipital region and another in the infrascapular area close to the ipsilateral armpit, with relief and irregular edges. Upon medical evaluation, she was diagnosed with infantile hemangioma. Infantile hemangioma is a common benign vascular tumour, representing the vascular anomaly most frequently found in children. This work aimed to show the action of homeopathic treatment with Calcárea Carbonica as a therapeutic option with good efficacy for the treatment of infantile hemangioma.

O uso da homeopatia em TDAH: relato de caso / The use of homeopathy in ADHD: case report

Esse trabalho apresenta um relato de caso de uma criança com diagnóstico de Transtorno de Déficit de Atenção e Hiperatividade (TDAH) e intervenção com homeopatia. O objetivo é verificar eficácia da homeopatia para o TDAH. Concluiu-se que a intervenção com homeopatia apresentou resultados significativos no tratamento deste caso, como aumento da atenção e do rendimento escolar, diminuição dos comportamentos impulsivos, trazendo consequências positivas para o indivíduo e o seu relacionamento familiar.

This works presents a case report of a child diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) and intervention with homeopathy. The objective is to verify the effectiveness of homeopathy for ADHD. It was concluded that the intervention with homeopathy showed significant results in the treatment of this case, such as increased attention and school performance, decreased impulsive behavior, bringing positive consequences for the individual and his family relationship.

Ceratodermia aquagênica: abordagem e tratamento homeopático: relato de caso / Aquagenic keratoderma: homeopathic approach and treatment: case report

"Homeopatia" é uma palavra de origem grega, introduzida por Hahnemann, onde homóis significa "semelhante" e pathos significa "sofrimento, doença". Considerado modelo terapêutico voltado ao indivíduo e não à doença. A relevância clínica da doença e o sucesso terapêutico motiva a realização do trabalho que relata um caso de paciente com distúrbio de pele raro, tratado com Sulphur e Petroleum. Os sintomas relatados pela paciente foram transformados em linguagem repertorial, elegendo-se as rubricas e respeitando as leis de hierarquização. O processo de repertorização ocorre de forma digital e com análise comparativa à matéria médica respeitando os processos de similitude. O sucesso da terapêutica pode ser observado pela evolução positiva da lesão descrita na queixa principal, e o reequilíbrio de sua homeostase, melhorando os aspectos emocional, físico e social.

"Homeopathy" is a word of Greek origin, introduced by Hahnemann, where homóis means "similar" and pathos means "suffering, disease". Considered a therapeutic model aimed at the individual and not the disease. The clinical relevance of the disease and the therapeutic success motivated the work that reports a case of a patient with a rare skin disorder, treated with Sulfur and Petroleum. The symptoms reported by the patient were transformed into repertory language, choosing the rubrics and respecting the hierarchical laws. The repertorization process takes place digitally and with comparative analysis to the materia medica respecting the similarity processes. The success of the therapy can be observed by the positive evolution of the lesion described in the main complaint, and the rebalancing of her vital energy, improving her emotional, physical and social aspects.

A Homeopatia e a febre / Homeopathy and fever

A febre é um sinal clínico muito associado à infecção, gerando grande número de atendimentos em emergências e consultórios, e uso indiscriminado de antipiréticos.É desencadeada pela ação de citocinas pirogênicas endógenas e exógenas, desempenhando funções protetoras no organismo e auxiliando na recuperação. Conhecendo a importância da febre no mecanismo imunológico, e com a intenção de aliviar o desconforto do paciente, o medicamento homeopático tem como finalidade restabelecer a força vital, acelerando o processo de cura. Dentre todos os medicamentos homeopáticos, o simillimum é encontrado através da totalidade sintomática do paciente.Neste trabalho listamos alguns dos principais medicamentos utilizados para o tratamento da febre e suas indicações.(AU)

Fever is a clinical symptom generally associated to infection, generating a large number of emergency cases and medical appointments, and an indiscriminate use of antipyretics. The fever is triggered by the action of endogenous and exogenous pyrogenic cytokines, performing protective functions in the organism and aiding in the recovery. Regarding the importance of the fever in the immune mechanism, and with the intent to relieve the discomfort of the patient, the homeopathic medicine aims to restore the vital force, accelerating the healing process. Among all homeopathic medicines, simillimum is found through totality of symptoms manifested by the patient.(AU)

Transtorno bipolar: abordagem e tratamento homeopático (relato de caso) / Bipolar disorder: approach and homeopathic treatment (case report)

Relato de um paciente portador de transtorno afetivo bipolar, em uso de medicação psicotrópica e em psicoterapia regular, que, após iniciar uso de Hyoscyamus niger 30 CH, apresentou melhora importante da sintomatologia maníaca, demonstrada através de redução de pontuação da Escala de Avaliação de mania de Bech-Rafaelsen. Portanto, o medicamento homeopático é uma opção de tratamento para o transtorno bipolar do humor e outros transtornos mentais graves.(AU)

A report of a patient with bipolar affective disorder, using psychotropic medication and regular psychotherapy, who, after starting Hyoscyamus niger 30 CH, presented an important improvement of the manic symptomatology, demonstrated through reduction of the Mania Rating Scale Of Bech-Rafaelsen. Therefore, the homeopathic medicine is a treatment option for bipolar disorder of mood and other serious mental disorders. (AU)

Transtorno explosivo intermitente: relato de caso com tratamento homeopático

Relato de caso de um paciente com diagnostico de transtorno explosivo intermitente, fechando o diagnostico pela CID X e DSM IV com melhora importante com o uso da homeopatia. (AU)

Case report of a patient diagnosed with intermittent explosive disorder, closing the diagnosis by CID X and DSM IV with an important improvement with the use of homeopathy. (AU)

Relato de caso de dermatose plantar tratado com oleander / Case report of oleander-treated plantar dermatosis

Trabalho realizado a partir do relato de caso de paciente com quadro de dermatose plantar de longa data, sem resposta ao tratamento padrão com corticoides tópicos, tratada com Oleander, com remissão do quadro. Discutido a escolha do medicamento, feita através do sistema Keynote. (AU)

This study was carried out from the case report of a paciente with long standing plantar dermatosis, who did not respond to the standard treatment with topical corticosteroids, treated with Oleander, with remission of the condition. Discussed the choice of medication, made through the Key note system. (AU)

Distúrbios do sona em crianças: Abordagem homeopática / Disorders of sona in children: homeopathic approach

Esta monografia tem por objetivo fazer uma compilação de dados existentes na literatura referentes a utilização do tratamento homeopático aplicado às desordens do sono em um faixa etária específica – a população pediátrica. Foi realizada busca por trabalhos científicos publicados em base de dados internacionais – PubMed, LILACs e SciELO. Foram utilizados ainda livros textos consagrados, tanto em Homeopatia e Desordens do Sono, na busca da informação. Inicialmente foi descrita a fisiologia normal do sono e as principais desordens do sono que acometem a população pediátrica. A seguir, foi realizado um levantamento de medicamentos da matéria médica utilizados para distúrbios do sono e sua aplicabilidade, além de descrição da consulta homeopática direcionada para os distúrbios do sono e as intervenções necessárias à higiene do sono.(AU)

This monograph aims to compile data on the literature concerning the use of homeopathic treatment applied to sleep disorders in a specific age group - the paediatric population. It was performed searching for scientific papers published in international databases – PubMed, LILACs and SciELO. Books that are reference in these subjects, Homeopathy and Sleep Disorders, were used in the search for information. Initially, normal sleep physiology was described, as well as the main sleep disorders that affect a paediatric population. Subsequently, a data compilation about medical material used for sleep disorders and their application was described, just as the description of the homeopathic consultation directed to sleep disorders and as interventions for sleep hygiene.(AU)

O uso dos medicamentos homeopáticos no controle e tratamento da cólica do lactente

Este trabalho apresenta uma revisão de literatura sobre o controle e tratamento das cólicas dos recém-nascidos com a prescrição de medicamentos homeopáticos, seus critérios de escolha e seus efeitos. (AU)

This paper presents a literature review on the control and treatment of colic in newborns with the prescription of homeopathic medicines, its selection criteria and their effects. (AU)

Estudio retrospectivo multicéntrico sobre la efectividad de la homeopatía en pacientes con neumonía / Multicenter retrospective study on the effectiveness of homeopathy in patients with pneumonia

El estudio está basado en 39 casos de pacientes diagnosticados con neumonía y tratados según el método establecido por Samuel Hahnemann en el Organon. Observa los medicamentos más frecuentemente indicados, teniendo en cuenta la repertorización individual de los síntomas de cada paciente en el cuadro agudo. Hace un estudio comparativo sobre la evolución de los pacientes en función de las potencias utilizadas (30CH y 6LM) y de la conveniencia, o no, de la continuidad del tratamiento hasta la ausencia total de los síntomas clínicos.

This study is grounded on 39 cases of patients with pneumonia, who have been treated according to the method established by Samuel Hahnemann in the Organon. I pointed to the most frequently indicated remedies to treat this condition, following the individual repertorization of the symptoms of each patient. I compared also the evolution of the cases depending of the use of 30CH or 6LM potencies. I also questioned the suitability of continuing the treatment once the clinical symptoms have vanished.

Estudio retrospectivo multicéntrico sobre la efectividad de la homeopatía en pacientes con neumonía / Multicenter retrospective study on the effectiveness of homeopathy in patients with pneumonia

El estudio está basado en 39 casos de pacientes diagnosticados con neumonía y tratados según el método establecido por Samuel Hahnemann en el Organon. Observa los medicamentos más frecuentemente indicados, teniendo en cuenta la repertorización individual de los síntomas de cada paciente en el cuadro agudo. Hace un estudio comparativo sobre la evolución de los pacientes en función de las potencias utilizadas (30CH y 6LM) y de la conveniencia, o no, de la continuidad del tratamiento hasta la ausencia total de los síntomas clínicos. (AU)

This study is grounded on 39 cases of patients with pneumonia, who have been treated according to the method established by Samuel Hahnemann in the Organon. I pointed to the most frequently indicated remedies to treat this condition, following the individual repertorization of the symptoms of each patient. I compared also the evolution of the cases depending of the use of 30CH or 6LM potencies. I also questioned the suitability of continuing the treatment once the clinical symptoms have vanished. (AU)