Search | Virtual Health Library

1.

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model.

Li, Chunfeng; Deng, Yong-Qiang; Wang, Shuo; Ma, Feng; Aliyari, Roghiyh; Huang, Xing-Yao; Zhang, Na-Na; Watanabe, Momoko; Dong, Hao-Long; Liu, Ping; Li, Xiao-Feng; Ye, Qing; Tian, Min; Hong, Shuai; Fan, Junwan; Zhao, Hui; Li, Lili; Vishlaghi, Neda; Buth, Jessie E; Au, Connie; Liu, Ying; Lu, Ning; Du, Peishuang; Qin, F Xiao-Feng; Zhang, Bo; Gong, Danyang; Dai, Xinghong; Sun, Ren; Novitch, Bennett G; Xu, Zhiheng; Qin, Cheng-Feng; Cheng, Genhong.

Immunity ; 46(3): 446-456, 2017 03 21.

Article in English | MEDLINE | ID: mdl-28314593

2.

Kynurenine-3-monooxygenase (KMO) broadly inhibits viral infections via triggering NMDAR/Ca2+ influx and CaMKII/ IRF3-mediated IFN-ß production.

Zhao, Jin; Chen, Jiaoshan; Wang, Congcong; Liu, Yajie; Li, Minchao; Li, Yanjun; Li, Ruiting; Han, Zirong; Wang, Junjian; Chen, Ling; Shu, Yuelong; Cheng, Genhong; Sun, Caijun.

PLoS Pathog ; 18(3): e1010366, 2022 03.

Article in English | MEDLINE | ID: mdl-35235615

3.

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.

Parvatiyar, Kislay; Zhang, Zhiqiang; Teles, Rosane M; Ouyang, Songying; Jiang, Yan; Iyer, Shankar S; Zaver, Shivam A; Schenk, Mirjam; Zeng, Shang; Zhong, Wenwan; Liu, Zhi-Jie; Modlin, Robert L; Liu, Yong-jun; Cheng, Genhong.

Nat Immunol ; 13(12): 1155-61, 2012 Dec.

Article in English | MEDLINE | ID: mdl-23142775

4.

Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1.

Zhang, Shilei; Wang, Jingfeng; Cheng, Genhong.

Proc Natl Acad Sci U S A ; 118(37)2021 09 14.

Article in English | MEDLINE | ID: mdl-34452991

5.

Early Introduction and Community Transmission of SARS-CoV-2 Omicron Variant, New York, New York, USA.

Liu, Dakai; Cheng, Yexiao; Zhou, Hangyu; Wang, Lulan; Fiel, Roberto Hurtado; Gruenstein, Yehudah; Luo, Jean Jingzi; Singh, Vishnu; Konadu, Eric; James, Keither; Lui, Calvin; Gao, Pengcheng; Urban, Carl; Prasad, Nishant; Segal-Maurer, Sorana; Wurzberger, Esther; Cheng, Genhong; Wu, Aiping; Rodgers, William Harry.

Emerg Infect Dis ; 29(2): 371-380, 2023 02.

Article in English | MEDLINE | ID: mdl-36692451

6.

Genomic annotation and molecular evolution of monkeypox virus outbreak in 2022.

Wang, Lulan; Shang, Jingzhe; Weng, Shenghui; Aliyari, Saba R; Ji, Chengyang; Cheng, Genhong; Wu, Aiping.

J Med Virol ; 95(1): e28036, 2023 01.

Article in English | MEDLINE | ID: mdl-35906185

7.

SERTAD3 induces proteasomal degradation of ZIKV capsid protein and represents a therapeutic target.

Sun, Nina; Zhang, Rong-Rong; Song, Guang-Yuan; Cai, Qiaomei; Aliyari, Saba R; Nielsen-Saines, Karin; Jung, Jae U; Yang, Heng; Cheng, Genhong; Qin, Cheng-Feng.

J Med Virol ; 95(2): e28451, 2023 02.

Article in English | MEDLINE | ID: mdl-36594413

8.

The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies.

Zhang, Shilei; Wang, Lulan; Cheng, Genhong.

Mol Ther ; 30(5): 1869-1884, 2022 05 04.

Article in English | MEDLINE | ID: mdl-35176485

9.

Cryo-EM structure of influenza virus RNA polymerase complex at 4.3 Å resolution.

Chang, Shenghai; Sun, Dapeng; Liang, Huanhuan; Wang, Jia; Li, Jun; Guo, Lu; Wang, Xiangli; Guan, Chengcheng; Boruah, Bhargavi M; Yuan, Lingmin; Feng, Feng; Yang, Mingrui; Wang, Lulan; Wang, Yao; Wojdyla, Justyna; Li, Lanjuan; Wang, Jiawei; Wang, Meitian; Cheng, Genhong; Wang, Hong-Wei; Liu, Yingfang.

Mol Cell ; 57(5): 925-935, 2015 Mar 05.

Article in English | MEDLINE | ID: mdl-25620561

10.

Sequence analysis of the emerging SARS-CoV-2 variant Omicron in South Africa.

Wang, Lulan; Cheng, Genhong.

J Med Virol ; 94(4): 1728-1733, 2022 04.

Article in English | MEDLINE | ID: mdl-34897752

11.

Potential intervariant and intravariant recombination of Delta and Omicron variants.

Wang, Lulan; Zhou, Hang-Yu; Li, Jia-Ying; Cheng, Ye-Xiao; Zhang, Shilei; Aliyari, Saba; Wu, Aiping; Cheng, Genhong.

J Med Virol ; 94(10): 4830-4838, 2022 10.

Article in English | MEDLINE | ID: mdl-35705528

12.

TCR Ligand Discovery via T-Scan.

Wang, Zhe; Cheng, Genhong; Li, Guideng.

Trends Immunol ; 40(12): 1075-1077, 2019 12.

Article in English | MEDLINE | ID: mdl-31699586

13.

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.

Liu, Su-Yang; Aliyari, Roghiyh; Chikere, Kelechi; Li, Guangming; Marsden, Matthew D; Smith, Jennifer K; Pernet, Olivier; Guo, Haitao; Nusbaum, Rebecca; Zack, Jerome A; Freiberg, Alexander N; Su, Lishan; Lee, Benhur; Cheng, Genhong.

Immunity ; 38(1): 92-105, 2013 Jan 24.

Article in English | MEDLINE | ID: mdl-23273844

14.

The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity.

Wang, Yaya; Shaked, Iftach; Stanford, Stephanie M; Zhou, Wenbo; Curtsinger, Julie M; Mikulski, Zbigniew; Shaheen, Zachary R; Cheng, Genhong; Sawatzke, Kristy; Campbell, Amanda M; Auger, Jennifer L; Bilgic, Hatice; Shoyama, Fernanda M; Schmeling, David O; Balfour, Henry H; Hasegawa, Kiminori; Chan, Andrew C; Corbett, John A; Binstadt, Bryce A; Mescher, Matthew F; Ley, Klaus; Bottini, Nunzio; Peterson, Erik J.

Immunity ; 39(1): 111-22, 2013 Jul 25.

Article in English | MEDLINE | ID: mdl-23871208

15.

Co-Infection with 4 Species of Mycobacteria Identified by Using Next-Generation Sequencing.

Wang, Lulan; Liu, Dakai; Yung, Lok; Rodriguez, George David; Prasad, Nishant; Segal-Maurer, Sorana; Singh, Vishnu; Vikram, Ellee; Zou, Angela; Cheng, Genhong; Rodgers, William Harry.

Emerg Infect Dis ; 27(11): 2948-2950, 2021 11.

Article in English | MEDLINE | ID: mdl-34670649

16.

Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding.

Ouyang, Songying; Song, Xianqiang; Wang, Yaya; Ru, Heng; Shaw, Neil; Jiang, Yan; Niu, Fengfeng; Zhu, Yanping; Qiu, Weicheng; Parvatiyar, Kislay; Li, Yang; Zhang, Rongguang; Cheng, Genhong; Liu, Zhi-Jie.

Immunity ; 36(6): 1073-86, 2012 Jun 29.

Article in English | MEDLINE | ID: mdl-22579474

17.

"Gut-skin"axis: understanding psoriasis from the gut.

Su, Yang; Zhang, Fan; Qin, Wen; Wu, Lun; Wang, Qiuhong; Cheng, Genhong; Kuang, Haixue.

Pharmazie ; 76(11): 523-527, 2021 11 01.

Article in English | MEDLINE | ID: mdl-34782035

18.

Combinatorial screening of a panel of FDA-approved drugs identifies several candidates with anti-Ebola activities.

Du, Xiaohong; Zuo, Xiangyang; Meng, Fang; Wu, Fei; Zhao, Xin; Li, Chunfeng; Cheng, Genhong; Qin, F Xiao-Feng.

Biochem Biophys Res Commun ; 522(4): 862-868, 2020 02 19.

Article in English | MEDLINE | ID: mdl-31806372

19.

Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction.

Chapon, Maxime; Parvatiyar, Kislay; Aliyari, Saba Roghiyh; Zhao, Jeffrey S; Cheng, Genhong.

J Virol ; 93(23)2019 12 01.

Article in English | MEDLINE | ID: mdl-31511375

20.

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

Zarnegar, Brian J; Wang, Yaya; Mahoney, Douglas J; Dempsey, Paul W; Cheung, Herman H; He, Jeannie; Shiba, Travis; Yang, Xiaolu; Yeh, Wen-Chen; Mak, Tak W; Korneluk, Robert G; Cheng, Genhong.

Nat Immunol ; 9(12): 1371-8, 2008 Dec.

Article in English | MEDLINE | ID: mdl-18997794

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