Search | Virtual Health Library

1.

TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.

Venturutti, Leandro; Teater, Matt; Zhai, Andrew; Chadburn, Amy; Babiker, Leena; Kim, Daleum; Béguelin, Wendy; Lee, Tak C; Kim, Youngjun; Chin, Christopher R; Yewdell, William T; Raught, Brian; Phillip, Jude M; Jiang, Yanwen; Staudt, Louis M; Green, Michael R; Chaudhuri, Jayanta; Elemento, Olivier; Farinha, Pedro; Weng, Andrew P; Nissen, Michael D; Steidl, Christian; Morin, Ryan D; Scott, David W; Privé, Gilbert G; Melnick, Ari M.

Cell ; 182(2): 297-316.e27, 2020 07 23.

Article in English | MEDLINE | ID: mdl-32619424

2.

Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis.

Roberto, Mark P; Varano, Gabriele; Vinas-Castells, Rosa; Holmes, Antony B; Kumar, Rahul; Pasqualucci, Laura; Farinha, Pedro; Scott, David W; Dominguez-Sola, David.

Immunity ; 54(8): 1807-1824.e14, 2021 08 10.

Article in English | MEDLINE | ID: mdl-34380064

3.

Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.

Yusufova, Nevin; Kloetgen, Andreas; Teater, Matt; Osunsade, Adewola; Camarillo, Jeannie M; Chin, Christopher R; Doane, Ashley S; Venters, Bryan J; Portillo-Ledesma, Stephanie; Conway, Joseph; Phillip, Jude M; Elemento, Olivier; Scott, David W; Béguelin, Wendy; Licht, Jonathan D; Kelleher, Neil L; Staudt, Louis M; Skoultchi, Arthur I; Keogh, Michael-Christopher; Apostolou, Effie; Mason, Christopher E; Imielinski, Marcin; Schlick, Tamar; David, Yael; Tsirigos, Aristotelis; Allis, C David; Soshnev, Alexey A; Cesarman, Ethel; Melnick, Ari M.

Nature ; 589(7841): 299-305, 2021 01.

Article in English | MEDLINE | ID: mdl-33299181

4.

TRAF3 loss-of-function reveals the noncanonical NF-κB pathway as a therapeutic target in diffuse large B cell lymphoma.

Li, Michael Y; Chong, Lauren C; Duns, Gerben; Lytle, Andrew; Woolcock, Bruce; Jiang, Aixiang; Telenius, Adèle; Ben-Neriah, Susana; Nawaz, Waqas; Slack, Graham W; Elisia, Ingrid; Viganò, Elena; Aoki, Tomohiro; Healy, Shannon; Krystal, Gerald; Venturutti, Leandro; Scott, David W; Steidl, Christian.

Proc Natl Acad Sci U S A ; 121(18): e2320421121, 2024 Apr 30.

Article in English | MEDLINE | ID: mdl-38662551

5.

Randomized Bendamustine-Rituximab(R) + Bortezomib Induction and R + Lenalidomide Maintenance for Mantle Cell Lymphoma.

Smith, Mitchell Reed; Jegede, Opeyemi; Martin, Peter; Till, Brian; Parekh, Samir; Yang, David T; Hsi, Eric D; Witzig, Thomas E; Dave, Sandeep S; Scott, David W; Hanson, Curtis A; Kostakoglu, Lale; Abdel Samad, Nizar N; Casulo, Carla; Bartlett, Nancy L; Caimi, Paolo F; Al Baghdadi, Tareq; Blum, Kristie; Romer, Mark; Inwards, David J; Lerner, Rachel; Wagner, Lynne; Little, Richard F; Friedberg, Jonathan W; Leonard, John P; Kahl, Brad S.

Blood ; 2024 May 31.

Article in English | MEDLINE | ID: mdl-38820500

6.

Motive and Opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements-an LLMPP study.

Hilton, Laura K; Collinge, Brett J; Ben-Neriah, Susana; Alduaij, Waleed; Shaalan, Haya; Weng, Andrew; Cruz, Manuela; Slack, Graham W; Farinha, Pedro; Miyata-Takata, Tomoko; Boyle, Merrill; Meissner, Barbara; Cook, James R; Ondrejka, Sarah L; Ott, German; Rosenwald, Andreas; Campo, Elías; Amador, Catalina; Greiner, Timothy C; Raess, Philipp W; Song, Joo Y; Inghirami, Giorgio Ga; Jaffe, Elaine S; Weisenburger, Dennis D; Chan, Wing C; Beiske, Klaus; Fu, Kai; Delabie, Jan; Pittaluga, Stafania; Iqbal, Javeed; Wright, George; Sehn, Laurie H; Savage, Kerry J; Mungall, Andrew J; Feldman, Andrew L; Staudt, Louis M; Steidl, Christian; Rimsza, Lisa M; Morin, Ryan D; Scott, David W.

Blood ; 2024 May 03.

Article in English | MEDLINE | ID: mdl-38701426

7.

ESQmodel: biologically informed evaluation of 2-D cell segmentation quality in multiplexed tissue images.

Lee, Eric; Lee, Dongkyu; Fan, Wayne; Lytle, Andrew; Fu, Yuxiang; Scott, David W; Steidl, Christian; Aparicio, Samuel; Roth, Andrew.

Bioinformatics ; 40(1)2024 01 02.

Article in English | MEDLINE | ID: mdl-38152895

8.

Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns.

Dreval, Kostiantyn; Hilton, Laura K; Cruz, Manuela; Shaalan, Haya; Ben-Neriah, Susana; Boyle, Merrill; Collinge, Brett; Coyle, Krysta M; Duns, Gerben; Farinha, Pedro; Grande, Bruno M; Meissner, Barbara; Pararajalingam, Prasath; Rushton, Christopher K; Slack, Graham W; Wong, Jasper; Mungall, Andrew J; Marra, Marco A; Connors, Joseph M; Steidl, Christian; Scott, David W; Morin, Ryan D.

Blood ; 142(6): 561-573, 2023 08 10.

Article in English | MEDLINE | ID: mdl-37084389

9.

Molecular determinants of clinical outcomes in a real-world diffuse large B-cell lymphoma population.

Alduaij, Waleed; Collinge, Brett; Ben-Neriah, Susana; Jiang, Aixiang; Hilton, Laura K; Boyle, Merrill; Meissner, Barbara; Chong, Lauren; Miyata-Takata, Tomoko; Slack, Graham W; Farinha, Pedro; Craig, Jeffrey W; Lytle, Andrew; Savage, Kerry J; Villa, Diego; Gerrie, Alina S; Freeman, Ciara L; Gascoyne, Randy D; Connors, Joseph M; Morin, Ryan D; Sehn, Laurie H; Mungall, Andrew J; Steidl, Christian; Scott, David W.

Blood ; 141(20): 2493-2507, 2023 05 18.

Article in English | MEDLINE | ID: mdl-36302166

10.

Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas.

Shah, Shivem B; Carlson, Christopher R; Lai, Kristine; Zhong, Zhe; Marsico, Grazia; Lee, Katherine M; Félix Vélez, Nicole E; Abeles, Elisabeth B; Allam, Mayar; Hu, Thomas; Walter, Lauren D; Martin, Karen E; Gandhi, Khanjan; Butler, Scott D; Puri, Rishi; McCleary-Wheeler, Angela L; Tam, Wayne; Elemento, Olivier; Takata, Katsuyoshi; Steidl, Christian; Scott, David W; Fontan, Lorena; Ueno, Hideki; Cosgrove, Benjamin D; Inghirami, Giorgio; García, Andrés J; Coskun, Ahmet F; Koff, Jean L; Melnick, Ari; Singh, Ankur.

Nat Mater ; 22(4): 511-523, 2023 04.

Article in English | MEDLINE | ID: mdl-36928381

11.

Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing.

Grants, Jennifer M; May, Christina; Bridgers, Josh; Huang, Shujun; Gillis, Sierra; Meissner, Barbara; Boyle, Merrill; Ben-Neriah, Susana; Hung, Stacy; Duns, Gerben; Hilton, Laura; Gerrie, Alina S; Marra, Marco; Kridel, Robert; Sabatini, Peter J B; Steidl, Christian; Scott, David W; Karsan, Aly.

Clin Chem ; 70(1): 273-284, 2024 01 04.

Article in English | MEDLINE | ID: mdl-38175592

12.

A gene expression-based model predicts outcome in children with intermediate-risk classical Hodgkin lymphoma.

Johnston, Rebecca L; Mottok, Anja; Chan, Fong Chun; Jiang, Aixiang; Diepstra, Arjan; Visser, Lydia; Telenius, Adèle; Gascoyne, Randy D; Friedman, Debra L; Schwartz, Cindy L; Kelly, Kara M; Scott, David W; Horton, Terzah M; Steidl, Christian.

Blood ; 139(6): 889-893, 2022 02 10.

Article in English | MEDLINE | ID: mdl-34662378

13.

Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma.

Aoki, Tomohiro; Chong, Lauren C; Takata, Katsuyoshi; Milne, Katy; Marshall, Ashley; Chavez, Elizabeth A; Miyata-Takata, Tomoko; Ben-Neriah, Susana; Unrau, Doria; Telenius, Adele; Boyle, Merrill; Weng, Andrew P; Savage, Kerry J; Scott, David W; Farinha, Pedro; Shah, Sohrab P; Nelson, Brad H; Steidl, Christian.

Proc Natl Acad Sci U S A ; 118(41)2021 10 12.

Article in English | MEDLINE | ID: mdl-34615710

14.

ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells.

Chung, Elaine Y L; Sartori, Giulio; Ponzoni, Maurilio; Cascione, Luciano; Priebe, Valdemar; Xu-Monette, Zijun Y; Fang, Xiaosheng; Zhang, Mingzhi; Visco, Carlo; Tzankov, Alexandar; Rinaldi, Andrea; Sgrignani, Jacopo; Zucca, Emanuele; Rossi, Davide; Cavalli, Andrea; Inghirami, Giorgio; Scott, David W; Young, Ken H; Bertoni, Francesco.

Br J Haematol ; 203(2): 244-254, 2023 Oct.

Article in English | MEDLINE | ID: mdl-37584198

15.

Novel precision medicine approaches and treatment strategies in hematological malignancies.

Rosenquist, Richard; Bernard, Elsa; Erkers, Tom; Scott, David W; Itzykson, Raphael; Rousselot, Philippe; Soulier, Jean; Hutchings, Martin; Östling, Päivi; Cavelier, Lucia; Fioretos, Thoas; Smedby, Karin E.

J Intern Med ; 294(4): 413-436, 2023 10.

Article in English | MEDLINE | ID: mdl-37424223

16.

Long-term results of PET-guided radiation in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP.

Freeman, Ciara L; Savage, Kerry J; Villa, Diego R; Scott, David W; Srour, Line; Gerrie, Alina S; Brown, Maura J; Slack, Graham W; Farinha, Pedro; Skinnider, Brian; Morris, James; Bénard, François; Aquino-Parsons, Christina; Lo, Andrea; Pickles, Tom; Wilson, Don C; Tonseth, Petter; Connors, Joseph M; Sehn, Laurie H.

Blood ; 137(7): 929-938, 2021 02 18.

Article in English | MEDLINE | ID: mdl-32871586

17.

Mutational landscape of gray zone lymphoma.

Sarkozy, Clémentine; Hung, Stacy S; Chavez, Elizabeth A; Duns, Gerben; Takata, Katsuyoshi; Chong, Lauren C; Aoki, Tomohiro; Jiang, Aixiang; Miyata-Takata, Tomoko; Telenius, Adèle; Slack, Graham W; Molina, Thierry Jo; Ben-Neriah, Susana; Farinha, Pedro; Dartigues, Peggy; Damotte, Diane; Mottok, Anja; Salles, Gilles A; Casasnovas, Rene-Olivier; Savage, Kerry J; Laurent, Camille; Scott, David W; Traverse-Glehen, Alexandra; Steidl, Christian.

Blood ; 137(13): 1765-1776, 2021 04 01.

Article in English | MEDLINE | ID: mdl-32961552

18.

Characterization of DLBCL with a PMBL gene expression signature.

Duns, Gerben; Viganò, Elena; Ennishi, Daisuke; Sarkozy, Clementine; Hung, Stacy S; Chavez, Elizabeth; Takata, Katsuyoshi; Rushton, Christopher; Jiang, Aixiang; Ben-Neriah, Susana; Woolcock, Bruce W; Slack, Graham W; Hsi, Eric D; Craig, Jeffrey W; Hilton, Laura K; Shah, Sohrab P; Farinha, Pedro; Mottok, Anja; Gascoyne, Randy D; Morin, Ryan D; Savage, Kerry J; Scott, David W; Steidl, Christian.

Blood ; 138(2): 136-148, 2021 07 15.

Article in English | MEDLINE | ID: mdl-33684939

19.

The impact of MYC and BCL2 structural variants in tumors of DLBCL morphology and mechanisms of false-negative MYC IHC.

Collinge, Brett; Ben-Neriah, Susana; Chong, Lauren; Boyle, Merrill; Jiang, Aixiang; Miyata-Takata, Tomoko; Farinha, Pedro; Craig, Jeffrey W; Slack, Graham W; Ennishi, Daisuke; Mottok, Anja; Meissner, Barbara; Chavez, Elizabeth A; Gerrie, Alina S; Villa, Diego; Freeman, Ciara; Savage, Kerry J; Sehn, Laurie H; Morin, Ryan D; Mungall, Andrew J; Gascoyne, Randy D; Marra, Marco A; Connors, Joseph M; Steidl, Christian; Scott, David W.

Blood ; 137(16): 2196-2208, 2021 04 22.

Article in English | MEDLINE | ID: mdl-33120427

20.

Denoising Non-Stationary Signals via Dynamic Multivariate Complex Wavelet Thresholding.

Raath, Kim C; Ensor, Katherine B; Crivello, Alena; Scott, David W.

Entropy (Basel) ; 25(11)2023 Nov 16.

Article in English | MEDLINE | ID: mdl-37998238

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