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1.
Macular neovascularization lesion type and vision outcomes in neovascular age-related macular degeneration: post hoc analysis of HARBOR.
Graefes Arch Clin Exp Ophthalmol
; 260(8): 2437-2447, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35239009
2.
Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors.
Invest New Drugs
; 39(6): 1587-1597, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34180037
3.
Phase 1 study of the MDM2 antagonist RO6839921 in patients with acute myeloid leukemia.
Invest New Drugs
; 38(5): 1430-1441, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32020437
4.
A phase 1 study of the MDM2 antagonist RO6839921, a pegylated prodrug of idasanutlin, in patients with advanced solid tumors.
Invest New Drugs
; 38(4): 1156-1165, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31734832
5.
Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study.
Lancet Oncol
; 20(4): 518-530, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30857956
6.
Heterogeneity in disease activity, frequency of treatments, and visual outcomes among patients with retinal vein occlusion: relationship between injection need and vision with as-needed ranibizumab.
Br J Ophthalmol
; 2024 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38290802
7.
Aqueous humour interleukin-6 and vision outcomes with anti-vascular endothelial growth factor therapy.
Eye (Lond)
; 2024 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38622330
8.
Fluctuations in central foveal thickness and association with vision outcomes with anti-VEGF therapy for nAMD: HARBOR post hoc analysis.
BMJ Open Ophthalmol
; 7(1): e000957, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35342822
9.
Acute myeloid leukemia patients' clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts.
Haematologica
; 101(5): e185-8, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26869629
10.
Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b studyâ.
Leuk Res
; 100: 106489, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33302031
11.
A single-center, open-label study investigating the excretion balance, pharmacokinetics, metabolism, and absolute bioavailability of a single oral dose of [14C]-labeled idasanutlin and an intravenous tracer dose of [13C]-labeled idasanutlin in a single cohort of patients with solid tumors.
Cancer Chemother Pharmacol
; 84(1): 93-103, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31062077
12.
Phase 1 summary of plasma concentration-QTc analysis for idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors and AML.
Cancer Chemother Pharmacol
; 81(3): 597-607, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29392451
13.
Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 81(3): 529-537, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29368050
14.
Effect of orlistat on fecal fat, fecal biliary acids, and colonic cell proliferation in obese subjects.
Clin Gastroenterol Hepatol
; 5(11): 1291-9, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17920338
15.
Drusen Characteristics and Age-Related Macular Degeneration in Fellow Eyes.
Ophthalmol Retina
; 6(10): 969-971, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35598859
16.
Effect of Food and Esomeprazole on the Pharmacokinetics of Alectinib, a Highly Selective ALK Inhibitor, in Healthy Subjects.
Clin Pharmacol Drug Dev
; 6(4): 388-397, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-27545320
17.
Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia.
Clin Cancer Res
; 22(4): 868-76, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26459177
18.
Impact of low-dose ritonavir on danoprevir pharmacokinetics: results of computer-based simulations and a clinical drug-drug interaction study.
Clin Pharmacokinet
; 51(7): 457-65, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22624502
19.
Chronic hepatitis C in patients with persistently normal alanine transaminase levels.
Clin Gastroenterol Hepatol
; 4(5): 645-52, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16630770
20.
Viral and metabolic factors influencing alanine aminotransferase activity in patients with chronic hepatitis C.
J Hepatol
; 44(4): 679-85, 2006 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-16487620
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