Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

An essential role for the Zn²⁺ transporter ZIP7 in B cell development.

Anzilotti, Consuelo; Swan, David J; Boisson, Bertrand; Deobagkar-Lele, Mukta; Oliveira, Catarina; Chabosseau, Pauline; Engelhardt, Karin R; Xu, Xijin; Chen, Rui; Alvarez, Luis; Berlinguer-Palmini, Rolando; Bull, Katherine R; Cawthorne, Eleanor; Cribbs, Adam P; Crockford, Tanya L; Dang, Tarana Singh; Fearn, Amy; Fenech, Emma J; de Jong, Sarah J; Lagerholm, B Christoffer; Ma, Cindy S; Sims, David; van den Berg, Bert; Xu, Yaobo; Cant, Andrew J; Kleiner, Gary; Leahy, T Ronan; de la Morena, M Teresa; Puck, Jennifer M; Shapiro, Ralph S; van der Burg, Mirjam; Chapman, J Ross; Christianson, John C; Davies, Benjamin; McGrath, John A; Przyborski, Stefan; Santibanez Koref, Mauro; Tangye, Stuart G; Werner, Andreas; Rutter, Guy A; Padilla-Parra, Sergi; Casanova, Jean-Laurent; Cornall, Richard J; Conley, Mary Ellen; Hambleton, Sophie.

Nat Immunol ; 20(3): 350-361, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30718914

2.

Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.

Yu, Vanessa; Yong, Fiona; Marta, Angellica; Khadayate, Sanjay; Osakwe, Adrien; Bhattacharya, Supriyo; Varghese, Sneha S; Chabosseau, Pauline; Tabibi, Sayed M; Chen, Keran; Georgiadou, Eleni; Parveen, Nazia; Suleiman, Mara; Stamoulis, Zoe; Marselli, Lorella; De Luca, Carmela; Tesi, Marta; Ostinelli, Giada; Delgadillo-Silva, Luis; Wu, Xiwei; Hatanaka, Yuki; Montoya, Alex; Elliott, James; Patel, Bhavik; Demchenko, Nikita; Whilding, Chad; Hajkova, Petra; Shliaha, Pavel; Kramer, Holger; Ali, Yusuf; Marchetti, Piero; Sladek, Robert; Dhawan, Sangeeta; Withers, Dominic J; Rutter, Guy A; Millership, Steven J.

Diabetologia ; 67(6): 1079-1094, 2024 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-38512414

3.

Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.

Nguyen-Tu, Marie-Sophie; Harris, Joseph; Martinez-Sanchez, Aida; Chabosseau, Pauline; Hu, Ming; Georgiadou, Eleni; Pollard, Alice; Otero, Pablo; Lopez-Noriega, Livia; Leclerc, Isabelle; Sakamoto, Kei; Schmoll, Dieter; Smith, David M; Carling, David; Rutter, Guy A.

Diabetologia ; 65(6): 997-1011, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35294578

4.

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.

Mousavy Gharavy, S Neda; Owen, Bryn M; Millership, Steven J; Chabosseau, Pauline; Pizza, Grazia; Martinez-Sanchez, Aida; Tasoez, Emirhan; Georgiadou, Eleni; Hu, Ming; Fine, Nicholas H F; Jacobson, David A; Dickerson, Matthew T; Idevall-Hagren, Olof; Montoya, Alex; Kramer, Holger; Mehta, Zenobia; Withers, Dominic J; Ninov, Nikolay; Gadue, Paul J; Cardenas-Diaz, Fabian L; Cruciani-Guglielmacci, Céline; Magnan, Christophe; Ibberson, Mark; Leclerc, Isabelle; Voz, Marianne; Rutter, Guy A.

Diabetologia ; 64(4): 850-864, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33492421

5.

The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.

Zhao, Lan; Oliver, Eduardo; Maratou, Klio; Atanur, Santosh S; Dubois, Olivier D; Cotroneo, Emanuele; Chen, Chien-Nien; Wang, Lei; Arce, Cristina; Chabosseau, Pauline L; Ponsa-Cobas, Joan; Frid, Maria G; Moyon, Benjamin; Webster, Zoe; Aldashev, Almaz; Ferrer, Jorge; Rutter, Guy A; Stenmark, Kurt R; Aitman, Timothy J; Wilkins, Martin R.

Nature ; 524(7565): 356-60, 2015 Aug 20.

Artículo en Inglés | MEDLINE | ID: mdl-26258299

6.

Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.

Kleiner, Sandra; Gomez, Daniel; Megra, Bezawit; Na, Erqian; Bhavsar, Ramandeep; Cavino, Katie; Xin, Yurong; Rojas, Jose; Dominguez-Gutierrez, Giselle; Zambrowicz, Brian; Carrat, Gaelle; Chabosseau, Pauline; Hu, Ming; Murphy, Andrew J; Yancopoulos, George D; Rutter, Guy A; Gromada, Jesper.

Proc Natl Acad Sci U S A ; 115(32): E7642-E7649, 2018 08 07.

Artículo en Inglés | MEDLINE | ID: mdl-30038024

7.

Importance of Both Imprinted Genes and Functional Heterogeneity in Pancreatic Beta Cells: Is There a Link?

Chabosseau, Pauline; Rutter, Guy A; Millership, Steven J.

Int J Mol Sci ; 22(3)2021 Jan 20.

Artículo en Inglés | MEDLINE | ID: mdl-33498234

8.

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.

Carrat, Gaelle R; Hu, Ming; Nguyen-Tu, Marie-Sophie; Chabosseau, Pauline; Gaulton, Kyle J; van de Bunt, Martijn; Siddiq, Afshan; Falchi, Mario; Thurner, Matthias; Canouil, Mickaël; Pattou, Francois; Leclerc, Isabelle; Pullen, Timothy J; Cane, Matthew C; Prabhala, Priyanka; Greenwald, William; Schulte, Anke; Marchetti, Piero; Ibberson, Mark; MacDonald, Patrick E; Manning Fox, Jocelyn E; Gloyn, Anna L; Froguel, Philippe; Solimena, Michele; McCarthy, Mark I; Rutter, Guy A.

Am J Hum Genet ; 100(2): 238-256, 2017 02 02.

Artículo en Inglés | MEDLINE | ID: mdl-28132686

9.

The transcription factor Pax6 is required for pancreatic ß cell identity, glucose-regulated ATP synthesis, and Ca²⁺ dynamics in adult mice.

Mitchell, Ryan K; Nguyen-Tu, Marie-Sophie; Chabosseau, Pauline; Callingham, Rebecca M; Pullen, Timothy J; Cheung, Rebecca; Leclerc, Isabelle; Hodson, David J; Rutter, Guy A.

J Biol Chem ; 292(21): 8892-8906, 2017 05 26.

Artículo en Inglés | MEDLINE | ID: mdl-28377501

10.

SLC30A9 mutation affecting intracellular zinc homeostasis causes a novel cerebro-renal syndrome.

Perez, Yonatan; Shorer, Zamir; Liani-Leibson, Keren; Chabosseau, Pauline; Kadir, Rotem; Volodarsky, Michael; Halperin, Daniel; Barber-Zucker, Shiran; Shalev, Hanna; Schreiber, Ruth; Gradstein, Libe; Gurevich, Evgenia; Zarivach, Raz; Rutter, Guy A; Landau, Daniel; Birk, Ohad S.

Brain ; 140(4): 928-939, 2017 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-28334855

11.

Local and regional control of calcium dynamics in the pancreatic islet.

Rutter, Guy A; Hodson, David J; Chabosseau, Pauline; Haythorne, Elizabeth; Pullen, Timothy J; Leclerc, Isabelle.

Diabetes Obes Metab ; 19 Suppl 1: 30-41, 2017 09.

Artículo en Inglés | MEDLINE | ID: mdl-28466490

12.

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the ß-cell are associated with glucose intolerance in humans and mice.

Mehta, Zenobia B; Fine, Nicholas; Pullen, Timothy J; Cane, Matthew C; Hu, Ming; Chabosseau, Pauline; Meur, Gargi; Velayos-Baeza, Antonio; Monaco, Anthony P; Marselli, Lorella; Marchetti, Piero; Rutter, Guy A.

Am J Physiol Endocrinol Metab ; 311(2): E488-507, 2016 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-27329800

13.

Zinc and diabetes.

Chabosseau, Pauline; Rutter, Guy A.

Arch Biochem Biophys ; 611: 79-85, 2016 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-27262257

14.

ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition.

Sui, Lina; Du, Qian; Romer, Anthony; Su, Qi; Chabosseau, Pauline L; Xin, Yurong; Kim, Jinrang; Kleiner, Sandra; Rutter, Guy A; Egli, Dieter.

Cells ; 12(6)2023 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-36980244

15.

Molecular phenotyping of single pancreatic islet leader beta cells by "Flash-Seq".

Chabosseau, Pauline; Yong, Fiona; Delgadillo-Silva, Luis F; Lee, Eun Young; Melhem, Rana; Li, Shiying; Gandhi, Nidhi; Wastin, Jules; Noriega, Livia Lopez; Leclerc, Isabelle; Ali, Yusuf; Hughes, Jing W; Sladek, Robert; Martinez-Sanchez, Aida; Rutter, Guy A.

Life Sci ; 316: 121436, 2023 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-36706832

16.

Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.

Yu, Vanessa; Yong, Fiona; Marta, Angellica; Khadayate, Sanjay; Osakwe, Adrien; Bhattacharya, Supriyo; Varghese, Sneha S; Chabosseau, Pauline; Tabibi, Sayed M; Chen, Keran; Georgiadou, Eleni; Parveen, Nazia; Suleiman, Mara; Stamoulis, Zoe; Marselli, Lorella; De Luca, Carmela; Tesi, Marta; Ostinelli, Giada; Delgadillo-Silva, Luis; Wu, Xiwei; Hatanaka, Yuki; Montoya, Alex; Elliott, James; Patel, Bhavik; Demchenko, Nikita; Whilding, Chad; Hajkova, Petra; Shliaha, Pavel; Kramer, Holger; Ali, Yusuf; Marchetti, Piero; Sladek, Robert; Dhawan, Sangeeta; Withers, Dominic J; Rutter, Guy A; Millership, Steven J.

bioRxiv ; 2023 Nov 30.

Artículo en Inglés | MEDLINE | ID: mdl-38076935

17.

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated ß-Cell Connectivity and Insulin Secretion.

Georgiadou, Eleni; Muralidharan, Charanya; Martinez, Michelle; Chabosseau, Pauline; Akalestou, Elina; Tomas, Alejandra; Wern, Fiona Yong Su; Stylianides, Theodoros; Wretlind, Asger; Legido-Quigley, Cristina; Jones, Ben; Lopez-Noriega, Livia; Xu, Yanwen; Gu, Guoqiang; Alsabeeh, Nour; Cruciani-Guglielmacci, Céline; Magnan, Christophe; Ibberson, Mark; Leclerc, Isabelle; Ali, Yusuf; Soleimanpour, Scott A; Linnemann, Amelia K; Rodriguez, Tristan A; Rutter, Guy A.

Diabetes ; 71(7): 1472-1489, 2022 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-35472764

18.

Glucose-Dependent miR-125b Is a Negative Regulator of ß-Cell Function.

Cheung, Rebecca; Pizza, Grazia; Chabosseau, Pauline; Rolando, Delphine; Tomas, Alejandra; Burgoyne, Thomas; Wu, Zhiyi; Salowka, Anna; Thapa, Anusha; Macklin, Annabel; Cao, Yufei; Nguyen-Tu, Marie-Sophie; Dickerson, Matthew T; Jacobson, David A; Marchetti, Piero; Shapiro, James; Piemonti, Lorenzo; de Koning, Eelco; Leclerc, Isabelle; Bouzakri, Karim; Sakamoto, Kei; Smith, David M; Rutter, Guy A; Martinez-Sanchez, Aida.

Diabetes ; 71(7): 1525-1545, 2022 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-35476777

19.

The Ca²⁺ -binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6.

Parks, Steven Z; Gao, Tian; Jimenez Awuapura, Natalia; Ayathamattam, Joseph; Chabosseau, Pauline L; Kalvakolanu, Dhananjaya V; Valdivia, Héctor H; Rutter, Guy A; Leclerc, Isabelle.

FEBS Lett ; 595(13): 1782-1796, 2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-33960419

20.

Intravital imaging of islet Ca²⁺ dynamics reveals enhanced ß cell connectivity after bariatric surgery in mice.

Akalestou, Elina; Suba, Kinga; Lopez-Noriega, Livia; Georgiadou, Eleni; Chabosseau, Pauline; Gallie, Alasdair; Wretlind, Asger; Legido-Quigley, Cristina; Leclerc, Isabelle; Salem, Victoria; Rutter, Guy A.

Nat Commun ; 12(1): 5165, 2021 08 27.

Artículo en Inglés | MEDLINE | ID: mdl-34453049

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An essential role for the Zn²⁺ transporter ZIP7 in B cell development.

Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.

Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.

The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.

Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.

Importance of Both Imprinted Genes and Functional Heterogeneity in Pancreatic Beta Cells: Is There a Link?

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.

The transcription factor Pax6 is required for pancreatic ß cell identity, glucose-regulated ATP synthesis, and Ca²⁺ dynamics in adult mice.

SLC30A9 mutation affecting intracellular zinc homeostasis causes a novel cerebro-renal syndrome.

Local and regional control of calcium dynamics in the pancreatic islet.

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the ß-cell are associated with glucose intolerance in humans and mice.

Zinc and diabetes.

ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition.

Molecular phenotyping of single pancreatic islet leader beta cells by "Flash-Seq".

Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated ß-Cell Connectivity and Insulin Secretion.

Glucose-Dependent miR-125b Is a Negative Regulator of ß-Cell Function.

The Ca²⁺ -binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6.

Intravital imaging of islet Ca²⁺ dynamics reveals enhanced ß cell connectivity after bariatric surgery in mice.