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1.
A riboswitch separated from its ribosome-binding site still regulates translation.
Nucleic Acids Res
; 51(5): 2464-2484, 2023 03 21.
Article
in English
| MEDLINE | ID: mdl-36762498
2.
Structure and function analysis of a type III preQ1-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence.
J Biol Chem
; 299(10): 105208, 2023 10.
Article
in English
| MEDLINE | ID: mdl-37660906
3.
Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res
; 50(9): 5299-5312, 2022 05 20.
Article
in English
| MEDLINE | ID: mdl-35524551
4.
Full-Length NAD+-I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate.
Biochemistry
; 62(23): 3396-3410, 2023 12 05.
Article
in English
| MEDLINE | ID: mdl-37947391
5.
A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
J Biol Chem
; 298(8): 102224, 2022 08.
Article
in English
| MEDLINE | ID: mdl-35780835
6.
Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation.
Nucleic Acids Res
; 48(14): 8146-8164, 2020 08 20.
Article
in English
| MEDLINE | ID: mdl-32597951
7.
Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J Biol Chem
; 295(50): 17148-17157, 2020 12 11.
Article
in English
| MEDLINE | ID: mdl-33020180
8.
Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J Biol Chem
; 295(49): 16470-16486, 2020 12 04.
Article
in English
| MEDLINE | ID: mdl-33051202
9.
Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction.
RNA
; 25(8): 1020-1037, 2019 08.
Article
in English
| MEDLINE | ID: mdl-31110137
10.
An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9, and LDLR in Hepatocytes.
Biochemistry
; 59(45): 4321-4335, 2020 11 17.
Article
in English
| MEDLINE | ID: mdl-33153264
11.
The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
J Biol Chem
; 294(8): 2892-2902, 2019 02 22.
Article
in English
| MEDLINE | ID: mdl-30567737
12.
Phosphatidic acid induces conformational changes in Sec18 protomers that prevent SNARE priming.
J Biol Chem
; 294(9): 3100-3116, 2019 03 01.
Article
in English
| MEDLINE | ID: mdl-30617180
13.
A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
J Biol Chem
; 294(46): 17168-17185, 2019 11 15.
Article
in English
| MEDLINE | ID: mdl-31515268
14.
Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures.
Trends Genet
; 33(5): 336-348, 2017 05.
Article
in English
| MEDLINE | ID: mdl-28372848
15.
Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes.
J Biol Chem
; 292(23): 9441-9450, 2017 06 09.
Article
in English
| MEDLINE | ID: mdl-28455443
16.
Correction: A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
J Biol Chem
; 298(11): 102576, 2022 Nov.
Article
in English
| MEDLINE | ID: mdl-36257250
17.
Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry
; 56(36): 4757-4761, 2017 09 12.
Article
in English
| MEDLINE | ID: mdl-28850223
18.
Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinositol-dependent kinase 1 regulates glycogen synthase kinase 3 activity: a novel mechanism of Akt activation.
FASEB J
; 30(8): 2926-44, 2016 08.
Article
in English
| MEDLINE | ID: mdl-27166089
19.
Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc Natl Acad Sci U S A
; 111(49): 17420-5, 2014 Dec 09.
Article
in English
| MEDLINE | ID: mdl-25422459
20.
Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding.
Biochem Biophys Res Commun
; 479(3): 551-556, 2016 Oct 21.
Article
in English
| MEDLINE | ID: mdl-27666481