Search details
1.
Structural and functional complexity of HSP90 in cellular homeostasis and disease.
Nat Rev Mol Cell Biol
; 24(11): 797-815, 2023 Nov.
Article
in English
| MEDLINE | ID: mdl-37524848
2.
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.
Mol Cell
; 53(2): 317-29, 2014 Jan 23.
Article
in English
| MEDLINE | ID: mdl-24462205
3.
HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts.
J Lipid Res
; 62: 100114, 2021.
Article
in English
| MEDLINE | ID: mdl-34481829
4.
The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis.
BMC Biol
; 18(1): 10, 2020 01 27.
Article
in English
| MEDLINE | ID: mdl-31987035
5.
Clients Place Unique Functional Constraints on Hsp90.
Trends Biochem Sci
; 41(7): 562-564, 2016 07.
Article
in English
| MEDLINE | ID: mdl-27297784
6.
Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
Mol Cell
; 47(3): 434-43, 2012 Aug 10.
Article
in English
| MEDLINE | ID: mdl-22727666
7.
A network of its own: the unique interactome of the Hsp90 cochaperone, Sba1/p23.
Mol Cell
; 43(2): 159-60, 2011 Jul 22.
Article
in English
| MEDLINE | ID: mdl-21777805
8.
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.
Mol Cell
; 41(6): 672-81, 2011 Mar 18.
Article
in English
| MEDLINE | ID: mdl-21419342
9.
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.
Mol Cell
; 37(3): 333-43, 2010 Feb 12.
Article
in English
| MEDLINE | ID: mdl-20159553
10.
The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation.
Immunity
; 28(6): 787-98, 2008 Jun.
Article
in English
| MEDLINE | ID: mdl-18549799
11.
Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma.
Hepatology
; 62(4): 1122-31, 2015 Oct.
Article
in English
| MEDLINE | ID: mdl-26058814
12.
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.
Mol Cell
; 31(6): 886-95, 2008 Sep 26.
Article
in English
| MEDLINE | ID: mdl-18922470
13.
Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex.
J Biol Chem
; 289(8): 4815-26, 2014 Feb 21.
Article
in English
| MEDLINE | ID: mdl-24379398
14.
Phase I study of the heat shock protein 90 (Hsp90) inhibitor onalespib (AT13387) administered on a daily for 2 consecutive days per week dosing schedule in patients with advanced solid tumors.
Invest New Drugs
; 33(4): 921-30, 2015 Aug.
Article
in English
| MEDLINE | ID: mdl-26082332
15.
Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.
Chemistry
; 21(39): 13598-608, 2015 Sep 21.
Article
in English
| MEDLINE | ID: mdl-26286886
16.
The complex dance of the molecular chaperone Hsp90.
Trends Biochem Sci
; 34(5): 223-6, 2009 May.
Article
in English
| MEDLINE | ID: mdl-19359180
17.
An update on the status of HSP90 inhibitors in cancer clinical trials.
Cell Stress Chaperones
; 2024 Jun 13.
Article
in English
| MEDLINE | ID: mdl-38878853
18.
Post-translational modifications of Hsp90 and their contributions to chaperone regulation.
Biochim Biophys Acta
; 1823(3): 648-55, 2012 Mar.
Article
in English
| MEDLINE | ID: mdl-21856339
19.
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90.
Nat Chem Biol
; 7(11): 818-26, 2011 Sep 25.
Article
in English
| MEDLINE | ID: mdl-21946277
20.
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.
Cancer Cell
; 8(2): 143-53, 2005 Aug.
Article
in English
| MEDLINE | ID: mdl-16098467