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1.
Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.
Blood
; 137(6): 830-843, 2021 02 11.
Article
in English
| MEDLINE | ID: mdl-32822477
2.
Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies.
Biotechnol Appl Biochem
; 70(1): 148-156, 2023 Feb.
Article
in English
| MEDLINE | ID: mdl-35324037
3.
Mitofusin-2 in cancer: Friend or foe?
Arch Biochem Biophys
; 730: 109395, 2022 11 15.
Article
in English
| MEDLINE | ID: mdl-36176224
4.
Computational and in vitro characterization of ICY-5: A potential candidate promoting mitochondrial apoptosis via the c-MET and STAT3 pathways.
J Cell Physiol
; 236(1): 146-156, 2021 01.
Article
in English
| MEDLINE | ID: mdl-32484605
5.
High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma.
J Comput Aided Mol Des
; 35(12): 1165-1176, 2021 12.
Article
in English
| MEDLINE | ID: mdl-34727304
6.
Identification of second generation benzylidene chromanone analogues as novel, potent DHODH inhibitors in acute myeloid leukemia cells.
J Biomol Struct Dyn
; 41(13): 6168-6177, 2023.
Article
in English
| MEDLINE | ID: mdl-35869648
7.
Identification by molecular dynamic simulation and in vitro validation of SISB-A1, N-[1-(4-bromophenyl)-3-methyl-1H-pyrazol-5-yl]-2-[(2-oxo-4-phenyl-2H-chromen-7-yl) oxy], as an inhibitor of the AblT315I mutant kinase to combat imatinib resistance in chronic myeloid leukemia.
Med Oncol
; 40(11): 316, 2023 Oct 03.
Article
in English
| MEDLINE | ID: mdl-37789230
8.
High-throughput screening and in vitro evaluation of CSB-0914; a novel small molecule NF-κB inhibitor attenuating inflammatory responses through NF-κB, Nrf2 and HO-1 cross-talk.
J Biomol Struct Dyn
; : 1-10, 2023 Dec 21.
Article
in English
| MEDLINE | ID: mdl-38127429
9.
High-throughput computational screening and in vitro evaluation identifies 5-(4-oxo-4H-3,1-benzoxazin-2-yl)-2-[3-(4-oxo-4H-3,1-benzoxazin-2-yl) phenyl]-1H-isoindole-1,3(2H)-dione (C3), as a novel EGFR-HER2 dual inhibitor in gastric tumors.
Oncol Res
; 32(2): 251-259, 2023.
Article
in English
| MEDLINE | ID: mdl-38186572
10.
Insilco and Invitro approaches identify novel dual PI3K/AKT pathway inhibitors to control acute myeloid leukemia cell proliferations.
Med Oncol
; 39(12): 249, 2022 Oct 08.
Article
in English
| MEDLINE | ID: mdl-36209300
11.
CB-RAF600E-1 exerts efficacy in vemurafenib-resistant and non-resistant-melanoma cells via dual inhibition of RAS/RAF/MEK/ERK and PI3K/Akt signaling pathways.
Saudi J Biol Sci
; 29(6): 103285, 2022 Jun.
Article
in English
| MEDLINE | ID: mdl-35592740
12.
FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling.
Pharmacol Rep
; 74(1): 96-110, 2022 Feb.
Article
in English
| MEDLINE | ID: mdl-34468975
13.
Mathematical modeling and stability analysis of the COVID-19 with quarantine and isolation.
Results Phys
; 34: 105284, 2022 Mar.
Article
in English
| MEDLINE | ID: mdl-35155087
14.
GC/MS characterization and computational kinome-wide screening of pomegranate fruit extract identifies key phytochemicals interacting to CDK kinases implicated in acute myeloid leukemia cells.
J Food Biochem
; 46(8): e14178, 2022 08.
Article
in English
| MEDLINE | ID: mdl-35451509
15.
Association of lncRNA LINC01173 Expression with Vitamin-D and Vitamin B12 Level Among Type 2 Diabetes Patients.
Diabetes Metab Syndr Obes
; 15: 2535-2543, 2022.
Article
in English
| MEDLINE | ID: mdl-36016630
16.
Cassia auriculata leaf extract ameliorates diabetic nephropathy by attenuating autophagic necroptosis via RIP-1/RIP-3-p-p38MAPK signaling.
J Food Biochem
; 45(7): e13810, 2021 07.
Article
in English
| MEDLINE | ID: mdl-34080203
17.
Anticancer efficacy of 3-(4-isopropyl) benzylidene-8-ethoxy, 6-methyl, chroman-4-one (SBL-060), a novel, dual, estrogen receptor-Akt kinase inhibitor in acute myeloid leukemia cells.
Oncol Res
; 29(3): 149-157, 2021.
Article
in English
| MEDLINE | ID: mdl-37304671
18.
Swertia chirayita suppresses the growth of non-small cell lung cancer A549 cells and concomitantly induces apoptosis via downregulation of JAK1/STAT3 pathway.
Saudi J Biol Sci
; 28(11): 6279-6288, 2021 Nov.
Article
in English
| MEDLINE | ID: mdl-34764752
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