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1.
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.
J Med Chem
; 65(24): 16801-16817, 2022 12 22.
Article
in English
| MEDLINE | ID: mdl-36475697
2.
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors.
J Med Chem
; 65(1): 838-856, 2022 01 13.
Article
in English
| MEDLINE | ID: mdl-34967623
3.
Discovery of (2R)-2-(3-{3-[(4-Methoxyphenyl)carbonyl]-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl}phenoxy)butanoic acid (MK-0533): a novel selective peroxisome proliferator-activated receptor gamma modulator for the treatment of type 2 diabetes mellitus with a reduced potential to increase plasma and extracellular fluid volume.
J Med Chem
; 52(13): 3846-54, 2009 Jul 09.
Article
in English
| MEDLINE | ID: mdl-19507861
4.
Benzoyl 2-methyl indoles as selective PPARgamma modulators.
Bioorg Med Chem Lett
; 15(2): 357-62, 2005 Jan 17.
Article
in English
| MEDLINE | ID: mdl-15603954
5.
Selective PPARgamma modulators with improved pharmacological profiles.
Bioorg Med Chem Lett
; 15(10): 2437-40, 2005 May 16.
Article
in English
| MEDLINE | ID: mdl-15863293
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