Search | VHL CLAP/WR-PAHO/WHO

1.

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.

Mou, Huihui; Quinlan, Brian D; Peng, Haiyong; Liu, Guanqun; Guo, Yan; Peng, Shoujiao; Zhang, Lizhou; Davis-Gardner, Meredith E; Gardner, Matthew R; Crynen, Gogce; DeVaux, Lindsey B; Voo, Zhi Xiang; Bailey, Charles C; Alpert, Michael D; Rader, Christoph; Gack, Michaela U; Choe, Hyeryun; Farzan, Michael.

PLoS Pathog ; 17(4): e1009501, 2021 04.

Article in English | MEDLINE | ID: mdl-33836016

2.

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.

Gardner, Matthew R; Kattenhorn, Lisa M; Kondur, Hema R; von Schaewen, Markus; Dorfman, Tatyana; Chiang, Jessica J; Haworth, Kevin G; Decker, Julie M; Alpert, Michael D; Bailey, Charles C; Neale, Ernest S; Fellinger, Christoph H; Joshi, Vinita R; Fuchs, Sebastian P; Martinez-Navio, Jose M; Quinlan, Brian D; Yao, Annie Y; Mouquet, Hugo; Gorman, Jason; Zhang, Baoshan; Poignard, Pascal; Nussenzweig, Michel C; Burton, Dennis R; Kwong, Peter D; Piatak, Michael; Lifson, Jeffrey D; Gao, Guangping; Desrosiers, Ronald C; Evans, David T; Hahn, Beatrice H; Ploss, Alexander; Cannon, Paula M; Seaman, Michael S; Farzan, Michael.

Nature ; 519(7541): 87-91, 2015 Mar 05.

Article in English | MEDLINE | ID: mdl-25707797

3.

An explanatory factor analysis of a brief self-report scale to detect neurocognitive impairment among HIV-positive men who have sex with men and transgender women in Peru.

Weikum, Damian; Shrestha, Roman; Ferro, Enrico G; Vagenas, Panagiotis; Copenhaver, Michael; Spudich, Serena; Alpert, Michael D; Cabello, Robinson; Lama, Javier R; Sanchez, Jorge; Altice, Frederick L.

AIDS Care ; 29(10): 1297-1301, 2017 10.

Article in English | MEDLINE | ID: mdl-28449599

4.

Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry.

Li, Qingsheng; Zeng, Ming; Duan, Lijie; Voss, James E; Smith, Anthony J; Pambuccian, Stefan; Shang, Liang; Wietgrefe, Stephen; Southern, Peter J; Reilly, Cavan S; Skinner, Pamela J; Zupancic, Mary L; Carlis, John V; Piatak, Michael; Waterman, Diane; Reeves, R Keith; Masek-Hammerman, Katherine; Derdeyn, Cynthia A; Alpert, Michael D; Evans, David T; Kohler, Heinz; Müller, Sybille; Robinson, James; Lifson, Jeffrey D; Burton, Dennis R; Johnson, R Paul; Haase, Ashley T.

J Immunol ; 193(6): 3113-25, 2014 Sep 15.

Article in English | MEDLINE | ID: mdl-25135832

5.

Legalization of Psychedelic Substances.

Alpert, Michael D.

JAMA ; 326(23): 2434, 2021 12 21.

Article in English | MEDLINE | ID: mdl-34932085

6.

Immune-correlates analysis of an HIV-1 vaccine efficacy trial.

Haynes, Barton F; Gilbert, Peter B; McElrath, M Juliana; Zolla-Pazner, Susan; Tomaras, Georgia D; Alam, S Munir; Evans, David T; Montefiori, David C; Karnasuta, Chitraporn; Sutthent, Ruengpueng; Liao, Hua-Xin; DeVico, Anthony L; Lewis, George K; Williams, Constance; Pinter, Abraham; Fong, Youyi; Janes, Holly; DeCamp, Allan; Huang, Yunda; Rao, Mangala; Billings, Erik; Karasavvas, Nicos; Robb, Merlin L; Ngauy, Viseth; de Souza, Mark S; Paris, Robert; Ferrari, Guido; Bailer, Robert T; Soderberg, Kelly A; Andrews, Charla; Berman, Phillip W; Frahm, Nicole; De Rosa, Stephen C; Alpert, Michael D; Yates, Nicole L; Shen, Xiaoying; Koup, Richard A; Pitisuttithum, Punnee; Kaewkungwal, Jaranit; Nitayaphan, Sorachai; Rerks-Ngarm, Supachai; Michael, Nelson L; Kim, Jerome H.

N Engl J Med ; 366(14): 1275-86, 2012 Apr 05.

Article in English | MEDLINE | ID: mdl-22475592

7.

ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.

Alpert, Michael D; Harvey, Jackson D; Lauer, W Anderson; Reeves, R Keith; Piatak, Michael; Carville, Angela; Mansfield, Keith G; Lifson, Jeffrey D; Li, Wenjun; Desrosiers, Ronald C; Johnson, R Paul; Evans, David T.

PLoS Pathog ; 8(8): e1002890, 2012.

Article in English | MEDLINE | ID: mdl-22927823

8.

In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.

Pan, Andi; Bailey, Charles C; Ou, Tianling; Xu, Jinge; Liu, Xin; Hu, Baodan; Crynen, Gogce; Skamangas, Nickolas; Bronkema, Naomi; Tran, Mai; Mu, Huihui; Zhang, Xia; Yin, Yiming; Alpert, Michael D; He, Wenhui; Farzan, Michael.

bioRxiv ; 2024 Feb 05.

Article in English | MEDLINE | ID: mdl-38370774

9.

In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.

Pan, Andi; Bailey, Charles C; Ou, Tianling; Xu, Jinge; Liu, Xin; Hu, Baodan; Crynen, Gogce; Skamangas, Nickolas; Bronkema, Naomi; Tran, Mai; Mu, Huihui; Zhang, Xia; Yin, Yiming; Alpert, Michael D; He, Wenhui; Farzan, Michael.

Res Sq ; 2024 Feb 09.

Article in English | MEDLINE | ID: mdl-38405717

10.

A novel assay for antibody-dependent cell-mediated cytotoxicity against HIV-1- or SIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays.

Alpert, Michael D; Heyer, Lisa N; Williams, David E J; Harvey, Jackson D; Greenough, Thomas; Allhorn, Maria; Evans, David T.

J Virol ; 86(22): 12039-52, 2012 Nov.

Article in English | MEDLINE | ID: mdl-22933282

11.

A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcÎ³RIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques.

Moldt, Brian; Shibata-Koyama, Mami; Rakasz, Eva G; Schultz, Niccole; Kanda, Yutaka; Dunlop, D Cameron; Finstad, Samantha L; Jin, Chenggang; Landucci, Gary; Alpert, Michael D; Dugast, Anne-Sophie; Parren, Paul W H I; Nimmerjahn, Falk; Evans, David T; Alter, Galit; Forthal, Donald N; Schmitz, Jörn E; Iida, Shigeru; Poignard, Pascal; Watkins, David I; Hessell, Ann J; Burton, Dennis R.

J Virol ; 86(11): 6189-96, 2012 Jun.

Article in English | MEDLINE | ID: mdl-22457527

12.

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family.

Bonsignori, Mattia; Pollara, Justin; Moody, M Anthony; Alpert, Michael D; Chen, Xi; Hwang, Kwan-Ki; Gilbert, Peter B; Huang, Ying; Gurley, Thaddeus C; Kozink, Daniel M; Marshall, Dawn J; Whitesides, John F; Tsao, Chun-Yen; Kaewkungwal, Jaranit; Nitayaphan, Sorachai; Pitisuttithum, Punnee; Rerks-Ngarm, Supachai; Kim, Jerome H; Michael, Nelson L; Tomaras, Georgia D; Montefiori, David C; Lewis, George K; DeVico, Anthony; Evans, David T; Ferrari, Guido; Liao, Hua-Xin; Haynes, Barton F.

J Virol ; 86(21): 11521-32, 2012 Nov.

Article in English | MEDLINE | ID: mdl-22896626

13.

Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium.

Callaway, Heather M; Hastie, Kathryn M; Schendel, Sharon L; Li, Haoyang; Yu, Xiaoying; Shek, Jeremy; Buck, Tierra; Hui, Sean; Bedinger, Dan; Troup, Camille; Dennison, S Moses; Li, Kan; Alpert, Michael D; Bailey, Charles C; Benzeno, Sharon; Bonnevier, Jody L; Chen, Jin-Qiu; Chen, Charm; Cho, Hyeseon; Crompton, Peter D; Dussupt, Vincent; Entzminger, Kevin C; Ezzyat, Yassine; Fleming, Jonathan K; Geukens, Nick; Gilbert, Amy E; Guan, Yongjun; Han, Xiaojian; Harvey, Christopher J; Hatler, Julia M; Howie, Bryan; Hu, Chao; Huang, Ailong; Imbrechts, Maya; Jin, Aishun; Kamachi, Nik; Keitany, Gladys; Klinger, Mark; Kolls, Jay K; Krebs, Shelly J; Li, Tingting; Luo, Feiyan; Maruyama, Toshiaki; Meehl, Michael A; Mendez-Rivera, Letzibeth; Musa, Andrea; Okumura, C J; Rubin, Benjamin E R; Sato, Aaron K; Shen, Meiying.

Cell Rep ; 42(1): 112014, 2023 01 31.

Article in English | MEDLINE | ID: mdl-36681898

14.

A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for FcÎ³ receptors to define the role of effector functions in protection against HIV.

Moldt, Brian; Schultz, Niccole; Dunlop, D Cameron; Alpert, Michael D; Harvey, Jackson D; Evans, David T; Poignard, Pascal; Hessell, Ann J; Burton, Dennis R.

J Virol ; 85(20): 10572-81, 2011 Oct.

Article in English | MEDLINE | ID: mdl-21849450

15.

Envelope-modified single-cycle simian immunodeficiency virus selectively enhances antibody responses and partially protects against repeated, low-dose vaginal challenge.

Alpert, Michael D; Rahmberg, Andrew R; Neidermyer, William; Ng, Sharon K; Carville, Angela; Camp, Jeremy V; Wilson, Robert L; Piatak, Michael; Mansfield, Keith G; Li, Wenjun; Miller, Christopher J; Lifson, Jeffrey D; Kozlowski, Pamela A; Evans, David T.

J Virol ; 84(20): 10748-64, 2010 Oct.

Article in English | MEDLINE | ID: mdl-20702641

16.

Availability of Buprenorphine Treatment in the 10 States With the Highest Drug Overdose Death Rates in the United States.

Flavin, Lila; Malowney, Monica; Patel, Nikhil A; Alpert, Michael D; Cheng, Elisa; Noy, Gaddy; Samuelson, Sarah; Sreshta, Nina; Boyd, J Wesley.

J Psychiatr Pract ; 26(1): 17-22, 2020 01.

Article in English | MEDLINE | ID: mdl-31913966

17.

AAV vectors engineered to target insulin receptor greatly enhance intramuscular gene delivery.

Jackson, Cody B; Richard, Audrey S; Ojha, Amrita; Conkright, Kimberly A; Trimarchi, Jeffrey M; Bailey, Charles C; Alpert, Michael D; Kay, Mark A; Farzan, Michael; Choe, Hyeryun.

Mol Ther Methods Clin Dev ; 19: 496-506, 2020 Dec 11.

Article in English | MEDLINE | ID: mdl-33313337

18.

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2.

Mou, Huihui; Quinlan, Brian D; Peng, Haiyong; Guo, Yan; Peng, Shoujiao; Zhang, Lizhou; Davis-Gardner, Meredith E; Gardner, Matthew R; Crynen, Gogce; Voo, Zhi Xiang; Bailey, Charles C; Alpert, Michael D; Rader, Christoph; Choe, Hyeryun; Farzan, Michael.

bioRxiv ; 2020 Jun 30.

Article in English | MEDLINE | ID: mdl-32637954

19.

A narrative-based approach to teaching diagnostic criteria.

Ross, David A; Alpert, Michael D; Edens, Ellen L.

Acad Psychiatry ; 38(6): 706-8, 2014 Dec.

Article in English | MEDLINE | ID: mdl-25501344

20.

Psychotherapy in Psychedelic Treatment: Safe, Evidence-Based, and Necessary.

Alpert, Michael D; O'Donnell, Kelley C; Paleos, Casey A; Sola, Evan; Stauffer, Christopher S; Wagner, Anne C; Nicholas, Christopher R; Mithoefer, Michael C.

Am J Psychiatry ; 181(1): 76-77, 2024 Jan 01.

Article in English | MEDLINE | ID: mdl-38161307

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Latin-American Center for Perinatology, Woman and Reproductive Health

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Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.

An explanatory factor analysis of a brief self-report scale to detect neurocognitive impairment among HIV-positive men who have sex with men and transgender women in Peru.

Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry.

Legalization of Psychedelic Substances.

Immune-correlates analysis of an HIV-1 vaccine efficacy trial.

ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.

In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.

In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.

A novel assay for antibody-dependent cell-mediated cytotoxicity against HIV-1- or SIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays.

A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcÎ³RIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques.

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family.

Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium.

A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for FcÎ³ receptors to define the role of effector functions in protection against HIV.

Envelope-modified single-cycle simian immunodeficiency virus selectively enhances antibody responses and partially protects against repeated, low-dose vaginal challenge.

Availability of Buprenorphine Treatment in the 10 States With the Highest Drug Overdose Death Rates in the United States.

AAV vectors engineered to target insulin receptor greatly enhance intramuscular gene delivery.

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2.

A narrative-based approach to teaching diagnostic criteria.

Psychotherapy in Psychedelic Treatment: Safe, Evidence-Based, and Necessary.