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1.
Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes.
Nat Immunol
; 21(10): 1244-1255, 2020 10.
Article
in English
| MEDLINE | ID: mdl-32747817
2.
Intramuscular AZD7442 (Tixagevimab-Cilgavimab) for Prevention of Covid-19.
N Engl J Med
; 386(23): 2188-2200, 2022 06 09.
Article
in English
| MEDLINE | ID: mdl-35443106
3.
Efficacy and safety of zibotentan and dapagliflozin in patients with chronic kidney disease: study design and baseline characteristics of the ZENITH-CKD trial.
Nephrol Dial Transplant
; 39(3): 414-425, 2024 Feb 28.
Article
in English
| MEDLINE | ID: mdl-37632201
4.
The effect of AZD9567 vs. prednisolone on glycaemic control in patients with type 2 diabetes mellitus: Results from a phase 2a clinical trial.
Br J Clin Pharmacol
; 2024 May 01.
Article
in English
| MEDLINE | ID: mdl-38690606
5.
Cardiometabolic risk management: insights from a European Society of Cardiology Cardiovascular Round Table.
Eur Heart J
; 44(39): 4141-4156, 2023 Oct 14.
Article
in English
| MEDLINE | ID: mdl-37448181
6.
Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19.
J Mol Cell Cardiol
; 167: 92-96, 2022 06.
Article
in English
| MEDLINE | ID: mdl-35339512
7.
The absolute risk of incident type 2 diabetes following exposure to systemic corticosteroids in selected steroid-related and phenotypic groups.
Diabetes Obes Metab
; 24(11): 2222-2231, 2022 11.
Article
in English
| MEDLINE | ID: mdl-35791627
8.
Efficacy and safety of cotadutide, a dual glucagon-like peptide-1 and glucagon receptor agonist, in a randomized phase 2a study of patients with type 2 diabetes and chronic kidney disease.
Diabetes Obes Metab
; 24(7): 1360-1369, 2022 07.
Article
in English
| MEDLINE | ID: mdl-35403793
9.
Pharmacokinetics, safety, tolerability and efficacy of cotadutide, a glucagon-like peptide-1 and glucagon receptor dual agonist, in phase 1 and 2 trials in overweight or obese participants of Asian descent with or without type 2 diabetes.
Diabetes Obes Metab
; 23(8): 1859-1867, 2021 08.
Article
in English
| MEDLINE | ID: mdl-33908687
10.
Effects of dapagliflozin on prevention of major clinical events and recovery in patients with respiratory failure because of COVID-19: Design and rationale for the DARE-19 study.
Diabetes Obes Metab
; 23(4): 886-896, 2021 04.
Article
in English
| MEDLINE | ID: mdl-33319454
11.
Endothelin antagonism and sodium glucose Co-transporter 2 inhibition. A potential combination therapeutic strategy for COVID-19.
Pulm Pharmacol Ther
; 69: 102035, 2021 08.
Article
in English
| MEDLINE | ID: mdl-33933611
12.
Randomised, phase 1, dose-finding study of MEDI4166, a PCSK9 antibody and GLP-1 analogue fusion molecule, in overweight or obese patients with type 2 diabetes mellitus.
Diabetologia
; 62(3): 373-386, 2019 03.
Article
in English
| MEDLINE | ID: mdl-30593607
13.
MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study.
Lancet
; 391(10140): 2607-2618, 2018 06 30.
Article
in English
| MEDLINE | ID: mdl-29945727
14.
A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
J Immunol
; 198(1): 528-537, 2017 01 01.
Article
in English
| MEDLINE | ID: mdl-27881707
15.
MEDI0382, a GLP-1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomized, Phase 1 study.
Br J Clin Pharmacol
; 84(10): 2325-2335, 2018 10.
Article
in English
| MEDLINE | ID: mdl-29926478
16.
Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
J Immunol
; 199(5): 1943, 2017 09 01.
Article
in English
| MEDLINE | ID: mdl-28827388
17.
A comprehensive analysis of liver safety across zibotentan oncology trials: knowledge of the past offers new perspectives on the present.
Expert Opin Drug Saf
; 23(4): 477-486, 2024 Apr.
Article
in English
| MEDLINE | ID: mdl-38469902
18.
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.
Biosci Rep
; 44(6)2024 Jun 26.
Article
in English
| MEDLINE | ID: mdl-38747277
19.
Glucagon and exenatide improve contractile recovery following ischaemia/reperfusion in the isolated perfused rat heart.
Physiol Rep
; 11(6): e15597, 2023 03.
Article
in English
| MEDLINE | ID: mdl-36946315
20.
Perspectives in weight control in diabetes - SGLT2 inhibitors and GLP-1-glucagon dual agonism.
Diabetes Res Clin Pract
; 199: 110669, 2023 May.
Article
in English
| MEDLINE | ID: mdl-37075928