Search details
1.
Agonists of prostaglandin E2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies.
Proc Natl Acad Sci U S A
; 119(18): e2115960119, 2022 05 03.
Article
in English
| MEDLINE | ID: mdl-35482924
2.
Repurposing small molecules for nephronophthisis and related renal ciliopathies.
Kidney Int
; 104(2): 245-253, 2023 08.
Article
in English
| MEDLINE | ID: mdl-37244473
3.
Synthesis and biological evaluation of (-)-6-O-desmethylcryptopleurine and analogs.
Bioorg Med Chem Lett
; 25(2): 184-7, 2015 Jan 15.
Article
in English
| MEDLINE | ID: mdl-25499434
4.
A genotype-to-phenotype approach suggests under-reporting of single nucleotide variants in nephrocystin-1 (NPHP1) related disease (UK 100,000 Genomes Project).
Sci Rep
; 13(1): 9369, 2023 06 09.
Article
in English
| MEDLINE | ID: mdl-37296294
5.
Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells.
Cancer Cell
; 6(2): 129-37, 2004 Aug.
Article
in English
| MEDLINE | ID: mdl-15324696
6.
Patient-Patient Similarity-Based Screening of a Clinical Data Warehouse to Support Ciliopathy Diagnosis.
Front Pharmacol
; 13: 786710, 2022.
Article
in English
| MEDLINE | ID: mdl-35401179
7.
Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase.
Anticancer Drugs
; 20(5): 364-72, 2009 Jun.
Article
in English
| MEDLINE | ID: mdl-19322071
8.
Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system.
Bioorg Med Chem Lett
; 19(9): 2474-7, 2009 May 01.
Article
in English
| MEDLINE | ID: mdl-19332372
9.
Potential mechanisms of resistance to microtubule inhibitors.
Semin Oncol
; 35(3 Suppl 3): S22-7, 2008 Jun.
Article
in English
| MEDLINE | ID: mdl-18538175
10.
Synthesis and biological evaluation of bengacarboline derivatives.
Bioorg Med Chem Lett
; 18(3): 1212-6, 2008 Feb 01.
Article
in English
| MEDLINE | ID: mdl-18083028
11.
P-glycoprotein, expressed in multidrug resistant cells, is not responsible for alterations in membrane fluidity or membrane potential.
Cancer Res
; 63(12): 3084-91, 2003 Jun 15.
Article
in English
| MEDLINE | ID: mdl-12810633
12.
F14512, a polyamine-vectorized inhibitor of topoisomerase II, exhibits a marked anti-tumor activity in ovarian cancer.
Cancer Lett
; 370(1): 10-8, 2016 Jan 01.
Article
in English
| MEDLINE | ID: mdl-26404751
13.
Regulation of melanocortin 1 receptor expression at the mRNA and protein levels by its natural agonist and antagonist.
FASEB J
; 17(14): 2154-6, 2003 Nov.
Article
in English
| MEDLINE | ID: mdl-14500544
14.
Different roles for K+ channels in cisplatin-resistant cell lines argue against a critical role for these channels in cisplatin resistance.
Anticancer Res
; 25(6B): 4113-22, 2005.
Article
in English
| MEDLINE | ID: mdl-16309205
15.
CD10 expression by melanoma cells is associated with aggressive behavior in vitro and predicts rapid metastatic progression in humans.
J Dermatol Sci
; 69(2): 105-13, 2013 Feb.
Article
in English
| MEDLINE | ID: mdl-23219141
16.
Melanoma chemotherapy leads to the selection of ABCB5-expressing cells.
PLoS One
; 7(5): e36762, 2012.
Article
in English
| MEDLINE | ID: mdl-22675422
17.
Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II.
Biochem Pharmacol
; 82(12): 1843-52, 2011 Dec 15.
Article
in English
| MEDLINE | ID: mdl-21924246
18.
Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.
Mol Cancer Ther
; 8(10): 2780-90, 2009 Oct.
Article
in English
| MEDLINE | ID: mdl-19808979
19.
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.
Cancer Res
; 68(23): 9845-53, 2008 Dec 01.
Article
in English
| MEDLINE | ID: mdl-19047165
20.
Physalin B, a novel inhibitor of the ubiquitin-proteasome pathway, triggers NOXA-associated apoptosis.
Biochem Pharmacol
; 76(4): 453-62, 2008 Aug 15.
Article
in English
| MEDLINE | ID: mdl-18577376