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1.
The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth.
EMBO J
; 35(17): 1902-22, 2016 09 01.
Article
in English
| MEDLINE | ID: mdl-27481935
2.
Towards 20,20-difluorinated bryostatin: synthesis and biological evaluation of C17,C27-fragments.
Org Biomol Chem
; 17(6): 1487-1505, 2019 02 06.
Article
in English
| MEDLINE | ID: mdl-30681118
3.
Going for broke: targeting the human cancer pseudokinome.
Biochem J
; 465(2): 195-211, 2015 Jan 15.
Article
in English
| MEDLINE | ID: mdl-25559089
4.
The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner.
Biochem J
; 467(1): 47-62, 2015 Apr 01.
Article
in English
| MEDLINE | ID: mdl-25583260
5.
The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth.
EMBO J
; 35(20): 2263, 2016 10 17.
Article
in English
| MEDLINE | ID: mdl-27798145
6.
Tribbles pseudokinases: novel targets for chemical biology and drug discovery?
Biochem Soc Trans
; 43(5): 1095-103, 2015 Oct.
Article
in English
| MEDLINE | ID: mdl-26517930
7.
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.
Biochem J
; 457(2): 323-34, 2014 Jan 15.
Article
in English
| MEDLINE | ID: mdl-24107129
8.
Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics.
Pigment Cell Melanoma Res
; 31(2): 253-266, 2018 03.
Article
in English
| MEDLINE | ID: mdl-28972303
9.
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.
Sci Signal
; 11(549)2018 09 25.
Article
in English
| MEDLINE | ID: mdl-30254057
10.
The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles.
Methods Enzymol
; 548: 117-46, 2014.
Article
in English
| MEDLINE | ID: mdl-25399644
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