Search details
1.
The Novel, Clinical-Stage Soluble Guanylate Cyclase Activator BI 685509 Protects from Disease Progression in Models of Renal Injury and Disease.
J Pharmacol Exp Ther
; 384(3): 382-392, 2023 03.
Article
in English
| MEDLINE | ID: mdl-36507845
2.
Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney.
J Am Soc Nephrol
; 32(3): 614-627, 2021 03.
Article
in English
| MEDLINE | ID: mdl-33531352
3.
Changes in Albuminuria But Not GFR are Associated with Early Changes in Kidney Structure in Type 2 Diabetes.
J Am Soc Nephrol
; 30(6): 1049-1059, 2019 06.
Article
in English
| MEDLINE | ID: mdl-31152118
4.
Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.
J Am Soc Nephrol
; 30(10): 2000-2016, 2019 10.
Article
in English
| MEDLINE | ID: mdl-31537649
5.
A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome.
Kidney Int
; 93(2): 439-449, 2018 02.
Article
in English
| MEDLINE | ID: mdl-29054530
6.
A Soluble Guanylate Cyclase Activator Inhibits the Progression of Diabetic Nephropathy in the ZSF1 Rat.
J Pharmacol Exp Ther
; 356(3): 712-9, 2016 Mar.
Article
in English
| MEDLINE | ID: mdl-26729306
7.
Rationale and design of the Transformative Research in Diabetic Nephropathy (TRIDENT) Study.
Kidney Int
; 97(1): 10-13, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31901339
8.
Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.
Arterioscler Thromb Vasc Biol
; 32(6): 1392-9, 2012 Jun.
Article
in English
| MEDLINE | ID: mdl-22460555
9.
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Nat Commun
; 13(1): 7497, 2022 12 05.
Article
in English
| MEDLINE | ID: mdl-36470928
10.
The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism.
J Transl Med
; 9: 180, 2011 Oct 21.
Article
in English
| MEDLINE | ID: mdl-22017794
11.
The key role of NLRP3 and STING in APOL1-associated podocytopathy.
J Clin Invest
; 131(20)2021 10 15.
Article
in English
| MEDLINE | ID: mdl-34651582
12.
Molecular characterization and cell type composition deconvolution of fibrosis in NAFLD.
Sci Rep
; 11(1): 18045, 2021 09 10.
Article
in English
| MEDLINE | ID: mdl-34508113
13.
C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization.
Bioorg Med Chem Lett
; 20(5): 1569-72, 2010 Mar 01.
Article
in English
| MEDLINE | ID: mdl-20149653
14.
Quantitative sphingosine measurement as a surrogate for total ceramide concentration-preclinical and potential translational applications.
Biomed Chromatogr
; 24(7): 752-8, 2010 Jul.
Article
in English
| MEDLINE | ID: mdl-19908207
15.
Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease.
Nat Med
; 24(11): 1721-1731, 2018 11.
Article
in English
| MEDLINE | ID: mdl-30275566
16.
Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.
Nat Med
; 23(4): 429-438, 2017 Apr.
Article
in English
| MEDLINE | ID: mdl-28218918
17.
Identification of (R)-6-(1-(4-cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic acid, a highly potent and selective nonsteroidal mineralocorticoid receptor antagonist.
J Med Chem
; 57(10): 4273-88, 2014 May 22.
Article
in English
| MEDLINE | ID: mdl-24738581
18.
PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy.
Front Pharmacol
; 4: 115, 2013.
Article
in English
| MEDLINE | ID: mdl-24133446
19.
Leptin potentiates the anti-obesity effects of rimonabant.
Eur J Pharmacol
; 658(2-3): 270-6, 2011 May 11.
Article
in English
| MEDLINE | ID: mdl-21371466
20.
Pharmacodynamic model of sodium-glucose transporter 2 (SGLT2) inhibition: implications for quantitative translational pharmacology.
AAPS J
; 13(4): 576-84, 2011 Dec.
Article
in English
| MEDLINE | ID: mdl-21870203