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1.
iBCS: 3. A Biopharmaceutics Classification System for Orally Inhaled Drug Products.
Mol Pharm
; 21(1): 164-172, 2024 Jan 01.
Article
in English
| MEDLINE | ID: mdl-38059771
2.
iBCS: 1. Principles and Framework of an Inhalation-Based Biopharmaceutics Classification System.
Mol Pharm
; 19(7): 2032-2039, 2022 07 04.
Article
in English
| MEDLINE | ID: mdl-35576168
3.
iBCS: 2. Mechanistic Modeling of Pulmonary Availability of Inhaled Drugs versus Critical Product Attributes.
Mol Pharm
; 19(7): 2040-2047, 2022 07 04.
Article
in English
| MEDLINE | ID: mdl-35609877
4.
Current practices for QSP model assessment: an IQ consortium survey.
J Pharmacokinet Pharmacodyn
; 2022 Aug 11.
Article
in English
| MEDLINE | ID: mdl-35953664
5.
Characterizing Pharmacokinetic-Pharmacodynamic Relationships and Efficacy of PI3Kδ Inhibitors in Respiratory Models of TH2 and TH1 Inflammation.
J Pharmacol Exp Ther
; 369(2): 223-233, 2019 05.
Article
in English
| MEDLINE | ID: mdl-30804001
6.
Mathematical Model of Bone Remodeling Captures the Antiresorptive and Anabolic Actions of Various Therapies.
Bull Math Biol
; 79(1): 117-142, 2017 01.
Article
in English
| MEDLINE | ID: mdl-27905067
7.
A combined physiologically-based pharmacokinetic and quantitative systems pharmacology model for modeling amyloid aggregation in Alzheimer's disease.
CPT Pharmacometrics Syst Pharmacol
; 12(4): 444-461, 2023 04.
Article
in English
| MEDLINE | ID: mdl-36632701
8.
Hallmarks of neurodegenerative disease: A systems pharmacology perspective.
CPT Pharmacometrics Syst Pharmacol
; 11(11): 1399-1429, 2022 11.
Article
in English
| MEDLINE | ID: mdl-35894182
9.
Long-term treatment with odanacatib maintains normal trabecular biomechanical properties in ovariectomized adult monkeys as demonstrated by micro-CT-based finite element analysis.
Bone Rep
; 6: 26-33, 2017 Jun.
Article
in English
| MEDLINE | ID: mdl-28377978
10.
Preclinical Experimental and Mathematical Approaches for Assessing Effective Doses of Inhaled Drugs, Using Mometasone to Support Human Dose Predictions.
J Aerosol Med Pulm Drug Deliv
; 29(4): 362-77, 2016 08.
Article
in English
| MEDLINE | ID: mdl-26859446
11.
Effects of odanacatib on the radius and tibia of postmenopausal women: improvements in bone geometry, microarchitecture, and estimated bone strength.
J Bone Miner Res
; 29(8): 1786-94, 2014 Aug.
Article
in English
| MEDLINE | ID: mdl-24643905
12.
A semimechanistic model of the time-course of release of PTH into plasma following administration of the calcilytic JTT-305/MK-5442 in humans.
J Bone Miner Res
; 28(8): 1830-6, 2013 Aug.
Article
in English
| MEDLINE | ID: mdl-23436611
13.
High-resolution peripheral quantitative computed tomography and finite element analysis of bone strength at the distal radius in ovariectomized adult rhesus monkey demonstrate efficacy of odanacatib and differentiation from alendronate.
Bone
; 56(2): 497-505, 2013 Oct.
Article
in English
| MEDLINE | ID: mdl-23791777
14.
Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: a head-to-head comparison with alendronate.
Bone
; 56(2): 489-96, 2013 Oct.
Article
in English
| MEDLINE | ID: mdl-23806798
15.
Evaluation of high-resolution peripheral quantitative computed tomography, finite element analysis and biomechanical testing in a pre-clinical model of osteoporosis: a study with odanacatib treatment in the ovariectomized adult rhesus monkey.
Bone
; 50(6): 1379-88, 2012 Jun.
Article
in English
| MEDLINE | ID: mdl-22469953
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