Search details
1.
Modeling Myotonic Dystrophy Type 2 Using Drosophila melanogaster.
Int J Mol Sci
; 24(18)2023 Sep 16.
Article
in English
| MEDLINE | ID: mdl-37762484
2.
A gene dosage-dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH-medulloblastoma.
Neuropathol Appl Neurobiol
; 48(6): e12837, 2022 10.
Article
in English
| MEDLINE | ID: mdl-35839783
3.
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies.
J Chem Inf Model
; 62(16): 3910-3927, 2022 08 22.
Article
in English
| MEDLINE | ID: mdl-35948439
4.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
EMBO J
; 34(2): 200-17, 2015 Jan 13.
Article
in English
| MEDLINE | ID: mdl-25476449
5.
Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance.
Int J Cancer
; 142(5): 968-975, 2018 03 01.
Article
in English
| MEDLINE | ID: mdl-29055107
6.
microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1.
EMBO J
; 32(21): 2819-32, 2013 Oct 30.
Article
in English
| MEDLINE | ID: mdl-24076654
7.
ß-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
BMC Cancer
; 17(1): 488, 2017 Jul 17.
Article
in English
| MEDLINE | ID: mdl-28716052
8.
Digging a hole under Hedgehog: downstream inhibition as an emerging anticancer strategy.
Biochim Biophys Acta
; 1856(1): 62-72, 2015 Aug.
Article
in English
| MEDLINE | ID: mdl-26080084
9.
Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
EMBO J
; 29(15): 2646-58, 2010 Aug 04.
Article
in English
| MEDLINE | ID: mdl-20581804
10.
SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Cell Death Differ
; 31(2): 170-187, 2024 02.
Article
in English
| MEDLINE | ID: mdl-38062245
11.
Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.
Cancers (Basel)
; 15(2)2023 Jan 06.
Article
in English
| MEDLINE | ID: mdl-36672319
12.
Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment: From synthesis to in vitro studies on neuroblastoma cell lines.
J Colloid Interface Sci
; 649: 264-278, 2023 Nov.
Article
in English
| MEDLINE | ID: mdl-37348346
13.
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
Cancer Lett
; 559: 216120, 2023 04 10.
Article
in English
| MEDLINE | ID: mdl-36893894
14.
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the ß-Catenin Armadillo Repeats Domain as an Anticancer Agent.
ACS Pharmacol Transl Sci
; 6(7): 1087-1103, 2023 Jul 14.
Article
in English
| MEDLINE | ID: mdl-37470018
15.
4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/ß-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells.
J Med Chem
; 66(21): 14824-14842, 2023 11 09.
Article
in English
| MEDLINE | ID: mdl-37902628
16.
Protected from the inside: endogenous histone deacetylase inhibitors and the road to cancer.
Biochim Biophys Acta
; 1815(2): 241-52, 2011 Apr.
Article
in English
| MEDLINE | ID: mdl-21277938
17.
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Proc Natl Acad Sci U S A
; 106(5): 1445-50, 2009 Feb 03.
Article
in English
| MEDLINE | ID: mdl-19164581
18.
The Mechanism of Action of Biguanides: New Answers to a Complex Question.
Cancers (Basel)
; 14(13)2022 Jun 30.
Article
in English
| MEDLINE | ID: mdl-35804992
19.
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment.
Eur J Med Chem
; 240: 114605, 2022 Oct 05.
Article
in English
| MEDLINE | ID: mdl-35868126
20.
Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-ß/Wnt3a Is Mediated by GLI2 Upregulation.
Cells
; 11(3)2022 02 03.
Article
in English
| MEDLINE | ID: mdl-35159339