Search details
1.
Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies.
Anal Chem
; 92(2): 2065-2073, 2020 01 21.
Article
in English
| MEDLINE | ID: mdl-31860282
2.
A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis.
Arthritis Rheum
; 64(6): 1730-9, 2012 Jun.
Article
in English
| MEDLINE | ID: mdl-22147649
3.
Pharmacokinetics and Pharmacodynamics of Burixafor Hydrobromide (GPC-100), a Novel C-X-C Chemokine Receptor 4 Antagonist and Mobilizer of Hematopoietic Stem/Progenitor Cells, in Mice and Healthy Subjects.
Clin Pharmacol Drug Dev
; 12(11): 1114-1120, 2023 11.
Article
in English
| MEDLINE | ID: mdl-37539772
4.
GPC-100, a novel CXCR4 antagonist, improves in vivo hematopoietic cell mobilization when combined with propranolol.
PLoS One
; 18(10): e0287863, 2023.
Article
in English
| MEDLINE | ID: mdl-37878624
5.
DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody-Drug Conjugate Modality.
ACS Med Chem Lett
; 12(3): 404-412, 2021 Mar 11.
Article
in English
| MEDLINE | ID: mdl-33738068
6.
A nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies.
Cancer Immunol Immunother
; 59(2): 257-65, 2010 Feb.
Article
in English
| MEDLINE | ID: mdl-19657637
7.
In vitro and in vivo characterization of MDX-1401 for therapy of malignant lymphoma.
Clin Cancer Res
; 15(10): 3376-83, 2009 May 15.
Article
in English
| MEDLINE | ID: mdl-19401346
8.
Glycan optimization of a human monoclonal antibody in the aquatic plant Lemna minor.
Nat Biotechnol
; 24(12): 1591-7, 2006 Dec.
Article
in English
| MEDLINE | ID: mdl-17128273
9.
Production of human monoclonal antibody in eggs of chimeric chickens.
Nat Biotechnol
; 23(9): 1159-69, 2005 Sep.
Article
in English
| MEDLINE | ID: mdl-16127450
10.
A Novel, Fully Human Anti-fucosyl-GM1 Antibody Demonstrates Potent In Vitro and In Vivo Antitumor Activity in Preclinical Models of Small Cell Lung Cancer.
Clin Cancer Res
; 24(20): 5178-5189, 2018 10 15.
Article
in English
| MEDLINE | ID: mdl-30021910
11.
CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors.
Cancer Res
; 63(17): 5526-31, 2003 Sep 01.
Article
in English
| MEDLINE | ID: mdl-14500390
12.
First-in-human multicenter phase I study of BMS-936561 (MDX-1203), an antibody-drug conjugate targeting CD70.
Cancer Chemother Pharmacol
; 77(1): 155-62, 2016 Jan.
Article
in English
| MEDLINE | ID: mdl-26576779
13.
Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.
PLoS One
; 11(11): e0167251, 2016.
Article
in English
| MEDLINE | ID: mdl-27861630
14.
Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.
PLoS One
; 11(9): e0161779, 2016.
Article
in English
| MEDLINE | ID: mdl-27610613
15.
Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway.
Oncotarget
; 7(3): 2809-22, 2016 Jan 19.
Article
in English
| MEDLINE | ID: mdl-26646452
16.
The receptor for type I IFNs is highly expressed on peripheral blood B cells and monocytes and mediates a distinct profile of differentiation and activation of these cells.
J Interferon Cytokine Res
; 24(2): 131-9, 2004 Feb.
Article
in English
| MEDLINE | ID: mdl-14980077
17.
Inhibition of tyrosine kinases blocks adhesion-induced T-cell coactivation without interfering with T-cell adhesion to endothelial cell-surface ligands.
Inflammation
; 26(1): 31-43, 2002 Feb.
Article
in English
| MEDLINE | ID: mdl-11936754
18.
Antibody-drug conjugates: current status and future directions.
Drug Discov Today
; 19(7): 869-81, 2014 Jul.
Article
in English
| MEDLINE | ID: mdl-24239727
19.
BMS-936564/MDX-1338: a fully human anti-CXCR4 antibody induces apoptosis in vitro and shows antitumor activity in vivo in hematologic malignancies.
Clin Cancer Res
; 19(2): 357-66, 2013 Jan 15.
Article
in English
| MEDLINE | ID: mdl-23213054
20.
Binding to CD20 by anti-B1 antibody or F(ab')(2) is sufficient for induction of apoptosis in B-cell lines.
Cancer Immunol Immunother
; 51(1): 15-24, 2002 Mar.
Article
in English
| MEDLINE | ID: mdl-11845256