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1.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.
J Biol Chem
; 299(3): 102888, 2023 03.
Article
in English
| MEDLINE | ID: mdl-36634849
2.
Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease.
J Virol
; 97(2): e0167222, 2023 02 28.
Article
in English
| MEDLINE | ID: mdl-36651748
3.
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.
Nucleic Acids Res
; 48(19): 10615-10631, 2020 11 04.
Article
in English
| MEDLINE | ID: mdl-32776089
4.
How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders.
Int J Mol Sci
; 22(9)2021 May 04.
Article
in English
| MEDLINE | ID: mdl-34064393
5.
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Proc Natl Acad Sci U S A
; 114(51): E11029-E11036, 2017 12 19.
Article
in English
| MEDLINE | ID: mdl-29203673
6.
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
EMBO J
; 34(24): 3028-41, 2015 Dec 14.
Article
in English
| MEDLINE | ID: mdl-26538322
7.
Tau reduction in the presence of amyloid-ß prevents tau pathology and neuronal death in vivo.
Brain
; 141(7): 2194-2212, 2018 07 01.
Article
in English
| MEDLINE | ID: mdl-29733334
8.
Enhanced Tau Aggregation in the Presence of Amyloid ß.
Am J Pathol
; 187(7): 1601-1612, 2017 Jul.
Article
in English
| MEDLINE | ID: mdl-28500862
9.
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Am J Pathol
; 187(6): 1399-1412, 2017 Jun.
Article
in English
| MEDLINE | ID: mdl-28408124
10.
Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.
Ann Neurol
; 80(3): 355-67, 2016 09.
Article
in English
| MEDLINE | ID: mdl-27351289
11.
Human tau increases amyloid ß plaque size but not amyloid ß-mediated synapse loss in a novel mouse model of Alzheimer's disease.
Eur J Neurosci
; 44(12): 3056-3066, 2016 12.
Article
in English
| MEDLINE | ID: mdl-27748574
12.
Caspase activation precedes and leads to tangles.
Nature
; 464(7292): 1201-4, 2010 Apr 22.
Article
in English
| MEDLINE | ID: mdl-20357768
13.
Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons.
Proc Natl Acad Sci U S A
; 110(46): 18698-703, 2013 Nov 12.
Article
in English
| MEDLINE | ID: mdl-24173031
14.
Innate immunity receptor CD36 promotes cerebral amyloid angiopathy.
Proc Natl Acad Sci U S A
; 110(8): 3089-94, 2013 Feb 19.
Article
in English
| MEDLINE | ID: mdl-23382216
15.
Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency.
Proc Natl Acad Sci U S A
; 109(23): 9035-40, 2012 Jun 05.
Article
in English
| MEDLINE | ID: mdl-22619325
16.
Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease.
J Neurosci
; 33(33): 13300-11, 2013 Aug 14.
Article
in English
| MEDLINE | ID: mdl-23946388
17.
Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model.
Acta Neuropathol
; 127(2): 257-70, 2014 Feb.
Article
in English
| MEDLINE | ID: mdl-24271788
18.
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
Proc Natl Acad Sci U S A
; 108(12): 5063-8, 2011 Mar 22.
Article
in English
| MEDLINE | ID: mdl-21383152
19.
Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.
PLoS Pathog
; 7(11): e1002391, 2011 Nov.
Article
in English
| MEDLINE | ID: mdl-22114562
20.
Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain.
Am J Pathol
; 179(4): 2071-82, 2011 Oct.
Article
in English
| MEDLINE | ID: mdl-21854751