Search details
1.
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
Cell
; 185(18): 3390-3407.e18, 2022 09 01.
Article
in English
| MEDLINE | ID: mdl-36055200
2.
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function.
Pharmacol Rev
; 73(1): 310-520, 2021 01.
Article
in English
| MEDLINE | ID: mdl-33370241
3.
Spatiotemporal dynamics of 5-HT6 receptor ciliary localization during mouse brain development.
Neurobiol Dis
; 176: 105949, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36496200
4.
Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT6 and D3R Affinity in the 1H-Pyrrolo[3,2-c]quinoline Series.
Molecules
; 28(3)2023 Jan 21.
Article
in English
| MEDLINE | ID: mdl-36770761
5.
Neuropathic pain-alleviating activity of novel 5-HT6 receptor inverse agonists derived from 2-aryl-1H-pyrrole-3-carboxamide.
Bioorg Chem
; 115: 105218, 2021 10.
Article
in English
| MEDLINE | ID: mdl-34365058
6.
Physical interaction between neurofibromin and serotonin 5-HT6 receptor promotes receptor constitutive activity.
Proc Natl Acad Sci U S A
; 113(43): 12310-12315, 2016 10 25.
Article
in English
| MEDLINE | ID: mdl-27791021
7.
A Serotonergic Axon-Cilium Synapse Drives Nuclear Signaling to Maintain Chromatin Accessibility.
Microsc Microanal
; 29(29 Suppl 1): 1091, 2023 Jul 22.
Article
in English
| MEDLINE | ID: mdl-37613506
8.
The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism.
Development
; 141(17): 3370-7, 2014 Sep.
Article
in English
| MEDLINE | ID: mdl-25078650
9.
Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth.
Nat Chem Biol
; 10(7): 590-7, 2014 Jul.
Article
in English
| MEDLINE | ID: mdl-24880860
10.
Impact of 5-HT6 Receptor Subcellular Localization on Its Signaling and Its Pathophysiological Roles.
Cells
; 12(3)2023 01 27.
Article
in English
| MEDLINE | ID: mdl-36766768
11.
Superiority of the Triple-Acting 5-HT6R/5-HT3R Antagonist and MAO-B Reversible Inhibitor PZ-1922 over 5-HT6R Antagonist Intepirdine in Alleviation of Cognitive Deficits in Rats.
J Med Chem
; 66(21): 14928-14947, 2023 11 09.
Article
in English
| MEDLINE | ID: mdl-37797083
12.
1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT6R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity.
Biomolecules
; 13(1)2022 12 21.
Article
in English
| MEDLINE | ID: mdl-36671397
13.
Novel and atypical pathways for serotonin signaling.
Fac Rev
; 10: 52, 2021.
Article
in English
| MEDLINE | ID: mdl-34195691
14.
Imidazopyridine-Based 5-HT6 Receptor Neutral Antagonists: Impact of N1-Benzyl and N1-Phenylsulfonyl Fragments on Different Receptor Conformational States.
J Med Chem
; 64(2): 1180-1196, 2021 01 28.
Article
in English
| MEDLINE | ID: mdl-33439019
15.
Amelioration of Tau pathology and memory deficits by targeting 5-HT7 receptor.
Prog Neurobiol
; 197: 101900, 2021 02.
Article
in English
| MEDLINE | ID: mdl-32841723
16.
Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT3 and 5-HT6 Receptor Antagonist with Antipsychotic and Procognitive Properties.
J Med Chem
; 64(18): 13279-13298, 2021 09 23.
Article
in English
| MEDLINE | ID: mdl-34467765
17.
2-Phenyl-1H-pyrrole-3-carboxamide as a New Scaffold for Developing 5-HT6 Receptor Inverse Agonists with Cognition-Enhancing Activity.
ACS Chem Neurosci
; 12(7): 1228-1240, 2021 04 07.
Article
in English
| MEDLINE | ID: mdl-33705101
18.
The 5-HT6 receptor interactome: New insight in receptor signaling and its impact on brain physiology and pathologies.
Neuropharmacology
; 172: 107839, 2020 08 01.
Article
in English
| MEDLINE | ID: mdl-31682856
19.
Dynamic interactions of the 5-HT6 receptor with protein partners control dendritic tree morphogenesis.
Sci Signal
; 13(618)2020 02 11.
Article
in English
| MEDLINE | ID: mdl-32047117
20.
mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment.
Prog Neurobiol
; 193: 101846, 2020 10.
Article
in English
| MEDLINE | ID: mdl-32512114