Search details
1.
Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature
; 570(7761): E53, 2019 Jun.
Article
in English
| MEDLINE | ID: mdl-31142845
2.
Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Bioorg Med Chem
; 100: 117618, 2024 Feb 15.
Article
in English
| MEDLINE | ID: mdl-38309201
3.
Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature
; 564(7736): 439-443, 2018 12.
Article
in English
| MEDLINE | ID: mdl-30405246
4.
New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.
Nat Chem Biol
; 11(11): 878-86, 2015 Nov.
Article
in English
| MEDLINE | ID: mdl-26436839
5.
Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition.
Bioorg Med Chem Lett
; 27(21): 4838-4843, 2017 11 01.
Article
in English
| MEDLINE | ID: mdl-28985999
6.
Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity.
Mol Pharmacol
; 88(6): 1011-23, 2015 Dec.
Article
in English
| MEDLINE | ID: mdl-26438213
7.
Mutant IDH1 enhances the production of 2-hydroxyglutarate due to its kinetic mechanism.
Biochemistry
; 52(26): 4563-77, 2013 Jul 02.
Article
in English
| MEDLINE | ID: mdl-23731180
8.
Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J Mol Biol
; 434(2): 167395, 2022 01 30.
Article
in English
| MEDLINE | ID: mdl-34896364
9.
A tale of two subunits: how the neomorphic R132H IDH1 mutation enhances production of αHG.
Biochemistry
; 50(21): 4804-12, 2011 May 31.
Article
in English
| MEDLINE | ID: mdl-21524095
10.
Kinetic mechanism and rate-limiting steps of focal adhesion kinase-1.
Biochemistry
; 49(33): 7151-63, 2010 Aug 24.
Article
in English
| MEDLINE | ID: mdl-20597513
11.
2,3,5-Trisubstituted pyridines as selective AKT inhibitors-Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity.
Bioorg Med Chem Lett
; 20(2): 673-8, 2010 Jan 15.
Article
in English
| MEDLINE | ID: mdl-20006497
12.
Discovery of 5-pyrrolopyridinyl-2-thiophenecarboxamides as potent AKT kinase inhibitors.
Bioorg Med Chem Lett
; 19(8): 2244-8, 2009 Apr 15.
Article
in English
| MEDLINE | ID: mdl-19285393
13.
Aminofurazans as potent inhibitors of AKT kinase.
Bioorg Med Chem Lett
; 19(5): 1508-11, 2009 Mar 01.
Article
in English
| MEDLINE | ID: mdl-19179070
14.
Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase.
Bioorg Med Chem Lett
; 19(15): 4350-3, 2009 Aug 01.
Article
in English
| MEDLINE | ID: mdl-19515564
15.
Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.
Cancer Cell
; 36(1): 100-114.e25, 2019 07 08.
Article
in English
| MEDLINE | ID: mdl-31257072
16.
3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
J Med Chem
; 49(3): 971-83, 2006 Feb 09.
Article
in English
| MEDLINE | ID: mdl-16451063
17.
Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
J Med Chem
; 59(15): 7299-304, 2016 Aug 11.
Article
in English
| MEDLINE | ID: mdl-27379833
18.
A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC.
Cancer Cell
; 28(1): 57-69, 2015 Jul 13.
Article
in English
| MEDLINE | ID: mdl-26175415
19.
Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO.
PLoS One
; 9(6): e98896, 2014.
Article
in English
| MEDLINE | ID: mdl-24896564
20.
Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase.
J Med Chem
; 51(18): 5663-79, 2008 Sep 25.
Article
in English
| MEDLINE | ID: mdl-18800763