Search details
1.
A comprehensive analysis of RAS-effector interactions reveals interaction hotspots and new binding partners.
J Biol Chem
; 296: 100626, 2021.
Article
in English
| MEDLINE | ID: mdl-33930461
2.
Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome.
Am J Hum Genet
; 104(6): 1223-1232, 2019 06 06.
Article
in English
| MEDLINE | ID: mdl-31130282
3.
The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands.
Biochem J
; 478(14): 2793-2809, 2021 07 30.
Article
in English
| MEDLINE | ID: mdl-34232285
4.
CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain.
Int J Mol Sci
; 23(16)2022 Aug 09.
Article
in English
| MEDLINE | ID: mdl-36012107
5.
Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes.
Am J Hum Genet
; 102(2): 309-320, 2018 02 01.
Article
in English
| MEDLINE | ID: mdl-29394990
6.
Selectivity Determinants of RHO GTPase Binding to IQGAPs.
Int J Mol Sci
; 22(22)2021 Nov 22.
Article
in English
| MEDLINE | ID: mdl-34830479
7.
Electrostatic Forces Mediate the Specificity of RHO GTPase-GDI Interactions.
Int J Mol Sci
; 22(22)2021 Nov 19.
Article
in English
| MEDLINE | ID: mdl-34830380
8.
Structural snapshots of RAF kinase interactions.
Biochem Soc Trans
; 46(6): 1393-1406, 2018 12 17.
Article
in English
| MEDLINE | ID: mdl-30381334
9.
Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J Biol Chem
; 291(39): 20353-71, 2016 09 23.
Article
in English
| MEDLINE | ID: mdl-27481945
10.
IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES.
J Biol Chem
; 291(51): 26364-26376, 2016 Dec 16.
Article
in English
| MEDLINE | ID: mdl-27815503
11.
The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties.
J Biol Chem
; 290(25): 15892-15903, 2015 Jun 19.
Article
in English
| MEDLINE | ID: mdl-25940089
12.
Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis.
Hum Mol Genet
; 23(16): 4315-27, 2014 Aug 15.
Article
in English
| MEDLINE | ID: mdl-24705357
13.
Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoforms.
Crit Rev Biochem Mol Biol
; 53(2): 130-156, 2018 04.
Article
in English
| MEDLINE | ID: mdl-29457927
14.
Functional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine finger.
J Biol Chem
; 289(10): 6839-6849, 2014 Mar 07.
Article
in English
| MEDLINE | ID: mdl-24443565
15.
Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes.
Hum Mol Genet
; 22(2): 262-70, 2013 Jan 15.
Article
in English
| MEDLINE | ID: mdl-23059812
16.
Deciphering the molecular and functional basis of Dbl family proteins: a novel systematic approach toward classification of selective activation of the Rho family proteins.
J Biol Chem
; 288(6): 4486-500, 2013 Feb 08.
Article
in English
| MEDLINE | ID: mdl-23255595
17.
Functional Classification and Interaction Selectivity Landscape of the Human SH3 Domain Superfamily.
Cells
; 13(2)2024 01 20.
Article
in English
| MEDLINE | ID: mdl-38275820
18.
SIRT4 as a novel interactor and candidate suppressor of C-RAF kinase in MAPK signaling.
Life Sci Alliance
; 7(6)2024 Jun.
Article
in English
| MEDLINE | ID: mdl-38499327
19.
Interaction characteristics of Plexin-B1 with Rho family proteins.
Biochem Biophys Res Commun
; 434(4): 785-90, 2013 May 17.
Article
in English
| MEDLINE | ID: mdl-23603360
20.
New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm.
Biol Chem
; 394(1): 89-95, 2013 Jan.
Article
in English
| MEDLINE | ID: mdl-23096567