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1.
Assessment of the Intestinal Absorption of Higher Olefins by the Everted Gut Sac Model in Combination with In Silico New Approach Methodologies.
Chem Res Toxicol
; 35(8): 1383-1392, 2022 08 15.
Article
in English
| MEDLINE | ID: mdl-35830964
2.
Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats.
Xenobiotica
; 49(2): 227-238, 2019 Feb.
Article
in English
| MEDLINE | ID: mdl-29424600
3.
Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator.
Crit Rev Toxicol
; 44(1): 64-82, 2014 Jan.
Article
in English
| MEDLINE | ID: mdl-24180433
4.
A Mechanism for the induction of renal tumours in male Fischer 344 rats by short-chain chlorinated paraffins.
Arch Toxicol
; 84(3): 233-43, 2010 Mar.
Article
in English
| MEDLINE | ID: mdl-20069279
5.
Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats following dietary exposure to ammonium perfluorooctanoate occurs through increased activation of the xenosensor nuclear receptors PPARα and CAR/PXR.
Arch Toxicol
; 84(10): 787-98, 2010 Oct.
Article
in English
| MEDLINE | ID: mdl-20614104
6.
Metazachlor: Mode of action analysis for rat liver tumour formation and human relevance.
Toxicology
; 426: 152282, 2019 10 01.
Article
in English
| MEDLINE | ID: mdl-31465819
7.
Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.
Toxicology
; 400-401: 20-27, 2018 05 01.
Article
in English
| MEDLINE | ID: mdl-29548889
8.
Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes.
Toxicology
; 396-397: 23-32, 2018 03 01.
Article
in English
| MEDLINE | ID: mdl-29425889
9.
Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA).
Toxicol Sci
; 163(1): 293-306, 2018 05 01.
Article
in English
| MEDLINE | ID: mdl-29462473
10.
Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes.
Toxicology
; 210(2-3): 147-57, 2005 Jun 01.
Article
in English
| MEDLINE | ID: mdl-15840428
11.
Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa.
J Histochem Cytochem
; 52(5): 653-62, 2004 May.
Article
in English
| MEDLINE | ID: mdl-15100242
12.
Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.
Environ Health Perspect
; 110(4): 363-75, 2002 Apr.
Article
in English
| MEDLINE | ID: mdl-11940454
13.
Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
Toxicol Sci
; 139(2): 501-11, 2014 Jun.
Article
in English
| MEDLINE | ID: mdl-24690595
14.
Identification of transcription factors and coactivators affected by dibutylphthalate interactions in fetal rat testes.
Toxicol Sci
; 132(2): 443-57, 2013 Apr.
Article
in English
| MEDLINE | ID: mdl-23358192
15.
Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.
Toxicol Sci
; 131(2): 375-86, 2013 Feb.
Article
in English
| MEDLINE | ID: mdl-23091169
16.
Evaluation of hepatic and thyroid responses in male Sprague Dawley rats for up to eighty-four days following seven days of dietary exposure to potassium perfluorooctanesulfonate.
Toxicology
; 293(1-3): 30-40, 2012 Mar 11.
Article
in English
| MEDLINE | ID: mdl-22239858
17.
Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats from dietary exposure to potassium perfluorooctanesulfonate results from increased expression of xenosensor nuclear receptors PPARα and CAR/PXR.
Toxicology
; 293(1-3): 16-29, 2012 Mar 11.
Article
in English
| MEDLINE | ID: mdl-22245121
18.
Transgenic animal models in toxicology: historical perspectives and future outlook.
Toxicol Sci
; 121(2): 207-33, 2011 Jun.
Article
in English
| MEDLINE | ID: mdl-21447610
19.
Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
Toxicol Sci
; 116(2): 452-66, 2010 Aug.
Article
in English
| MEDLINE | ID: mdl-20403969
20.
Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase.
Biochem J
; 373(Pt 2): 559-69, 2003 Jul 15.
Article
in English
| MEDLINE | ID: mdl-12720545