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1.
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication.
Mol Cell
; 82(9): 1631-1642.e6, 2022 05 05.
Article
in English
| MEDLINE | ID: mdl-35316659
2.
Integrative Molecular Structure Elucidation and Construction of an Extended Metabolic Pathway Associated with an Ancient Innate Immune Response in COVID-19 Patients.
J Proteome Res
; 23(3): 956-970, 2024 Mar 01.
Article
in English
| MEDLINE | ID: mdl-38310443
3.
Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems.
Mol Cell
; 64(6): 1102-1108, 2016 12 15.
Article
in English
| MEDLINE | ID: mdl-27867010
4.
Chemical Synthesis of the Antiviral Nucleotide Analogue ddhCTP.
J Org Chem
; 86(13): 8843-8850, 2021 07 02.
Article
in English
| MEDLINE | ID: mdl-34126010
5.
A single point mutation converts a glutaryl-7-aminocephalosporanic acid acylase into an N-acyl-homoserine lactone acylase.
Biotechnol Lett
; 43(7): 1467-1473, 2021 Jul.
Article
in English
| MEDLINE | ID: mdl-33891232
6.
Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis.
Biochemistry
; 59(27): 2562-2575, 2020 07 14.
Article
in English
| MEDLINE | ID: mdl-32627538
7.
Transition State Analogues Enhanced by Fragment-Based Structural Analysis: Bacterial Methylthioadenosine Nucleosidases.
Biochemistry
; 59(7): 831-835, 2020 02 25.
Article
in English
| MEDLINE | ID: mdl-32022543
8.
E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.
Gastric Cancer
; 22(2): 273-286, 2019 03.
Article
in English
| MEDLINE | ID: mdl-30066183
9.
Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc Natl Acad Sci U S A
; 113(48): 13756-13761, 2016 11 29.
Article
in English
| MEDLINE | ID: mdl-27856757
10.
Primordial-like enzymes from bacteria with reduced genomes.
Mol Microbiol
; 105(4): 508-524, 2017 Aug.
Article
in English
| MEDLINE | ID: mdl-28640457
11.
Transition State Analogue Inhibitors of 5'-Deoxyadenosine/5'-Methylthioadenosine Nucleosidase from Mycobacterium tuberculosis.
Biochemistry
; 56(38): 5090-5098, 2017 09 26.
Article
in English
| MEDLINE | ID: mdl-28836767
12.
A Designed Approach to Enantiodivergent Enamine Catalysis.
Angew Chem Int Ed Engl
; 56(30): 8756-8760, 2017 07 17.
Article
in English
| MEDLINE | ID: mdl-28544165
13.
Two-step Ligand Binding in a (ßα)8 Barrel Enzyme: SUBSTRATE-BOUND STRUCTURES SHED NEW LIGHT ON THE CATALYTIC CYCLE OF HisA.
J Biol Chem
; 290(41): 24657-68, 2015 Oct 09.
Article
in English
| MEDLINE | ID: mdl-26294764
14.
Distortional binding of transition state analogs to human purine nucleoside phosphorylase probed by magic angle spinning solid-state NMR.
Proc Natl Acad Sci U S A
; 110(40): 15991-6, 2013 Oct 01.
Article
in English
| MEDLINE | ID: mdl-24043827
15.
New Antibiotic Candidates against Helicobacter pylori.
J Am Chem Soc
; 137(45): 14275-80, 2015 Nov 18.
Article
in English
| MEDLINE | ID: mdl-26494017
16.
Tight binding enantiomers of pre-clinical drug candidates.
Bioorg Med Chem
; 23(17): 5326-33, 2015 Sep 01.
Article
in English
| MEDLINE | ID: mdl-26260335
17.
Inhibition and structure of Toxoplasma gondii purine nucleoside phosphorylase.
Eukaryot Cell
; 13(5): 572-9, 2014 May.
Article
in English
| MEDLINE | ID: mdl-24585883
18.
Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases.
J Biol Chem
; 288(48): 34746-54, 2013 Nov 29.
Article
in English
| MEDLINE | ID: mdl-24158442
19.
Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase.
Biochemistry
; 52(46): 8313-22, 2013 Nov 19.
Article
in English
| MEDLINE | ID: mdl-24148083
20.
Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Bioorg Med Chem
; 21(17): 5629-46, 2013 Sep 01.
Article
in English
| MEDLINE | ID: mdl-23810424