Search details
1.
A Reactive Antibody Platform for One-Step Production of Antibody-Drug Conjugates through a Diels-Alder Reaction with Maleimide.
Bioconjug Chem
; 30(9): 2340-2348, 2019 09 18.
Article
in English
| MEDLINE | ID: mdl-31380623
2.
Targeted Fcγ Receptor (FcγR)-mediated Clearance by a Biparatopic Bispecific Antibody.
J Biol Chem
; 292(10): 4361-4370, 2017 03 10.
Article
in English
| MEDLINE | ID: mdl-28100773
3.
Tuning the Diels-Alder Reaction for Bioconjugation to Maleimide Drug-Linkers.
Bioconjug Chem
; 29(7): 2406-2414, 2018 07 18.
Article
in English
| MEDLINE | ID: mdl-29932647
4.
Efficient Preparation of Site-Specific Antibody-Drug Conjugates Using Cysteine Insertion.
Mol Pharm
; 14(5): 1501-1516, 2017 05 01.
Article
in English
| MEDLINE | ID: mdl-28245132
5.
Antitumor activity of AZD0754, a dnTGFßRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.
J Clin Invest
; 133(22)2023 11 15.
Article
in English
| MEDLINE | ID: mdl-37966111
6.
Design and characterization of homogenous antibody-drug conjugates with a drug-to-antibody ratio of one prepared using an engineered antibody and a dual-maleimide pyrrolobenzodiazepine dimer.
MAbs
; 11(3): 500-515, 2019 04.
Article
in English
| MEDLINE | ID: mdl-30835621
7.
Improved Therapeutic Window in BRCA-mutant Tumors with Antibody-linked Pyrrolobenzodiazepine Dimers with and without PARP Inhibition.
Mol Cancer Ther
; 18(1): 89-99, 2019 01.
Article
in English
| MEDLINE | ID: mdl-30352801
8.
Insertion of scFv into the hinge domain of full-length IgG1 monoclonal antibody results in tetravalent bispecific molecule with robust properties.
MAbs
; 9(2): 240-256, 2017.
Article
in English
| MEDLINE | ID: mdl-27981887
9.
Amifostine (ETHYOL) protects rats from mucositis resulting from fractionated or hyperfractionated radiation exposure.
Int J Radiat Oncol Biol Phys
; 61(3): 901-7, 2005 Mar 01.
Article
in English
| MEDLINE | ID: mdl-15708273
10.
Preclinical modeling of improved amifostine (Ethyol) use in radiation therapy.
Semin Radiat Oncol
; 12(1 Suppl 1): 97-102, 2002 Jan.
Article
in English
| MEDLINE | ID: mdl-11917293
11.
Preclinical studies on the radioprotective efficacy and pharmacokinetics of subcutaneously administered amifostine.
Semin Oncol
; 29(6 Suppl 19): 2-8, 2002 Dec.
Article
in English
| MEDLINE | ID: mdl-12577236
12.
Effects of dose and schedule on the efficacy of ethyol: preclinical studies.
Semin Oncol
; 30(6 Suppl 18): 31-9, 2003 Dec.
Article
in English
| MEDLINE | ID: mdl-14727238
13.
Subcutaneous administration of amifostine (ethyol) is equivalent to intravenous administration in a rat mucositis model.
Int J Radiat Oncol Biol Phys
; 57(3): 794-802, 2003 Nov 01.
Article
in English
| MEDLINE | ID: mdl-14529786
14.
MEDI-573, alone or in combination with mammalian target of rapamycin inhibitors, targets the insulin-like growth factor pathway in sarcomas.
Mol Cancer Ther
; 13(11): 2662-73, 2014 Nov.
Article
in English
| MEDLINE | ID: mdl-25193511
15.
MEDI3617, a human anti-angiopoietin 2 monoclonal antibody, inhibits angiogenesis and tumor growth in human tumor xenograft models.
Int J Oncol
; 40(5): 1321-30, 2012 May.
Article
in English
| MEDLINE | ID: mdl-22327175
16.
Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2-positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib.
Mol Cancer Ther
; 8(8): 2131-41, 2009 Aug.
Article
in English
| MEDLINE | ID: mdl-19671750
17.
Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors.
Neoplasia
; 11(6): 509-17, 2 p following 517, 2009 Jun.
Article
in English
| MEDLINE | ID: mdl-19484140
18.
EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma.
J Natl Cancer Inst
; 101(17): 1193-205, 2009 Sep 02.
Article
in English
| MEDLINE | ID: mdl-19641174
19.
A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo.
Cancer Res
; 68(22): 9367-74, 2008 Nov 15.
Article
in English
| MEDLINE | ID: mdl-19010911
20.
Tissue levels of WR-1065, the active metabolite of amifostine (Ethyol), are equivalent following intravenous or subcutaneous administration in cynomolgus monkeys.
Oncology
; 67(3-4): 187-93, 2004.
Article
in English
| MEDLINE | ID: mdl-15557777
Results
1 -
20
de 20
1
Next >
>>