Search details
1.
SUMOylation of pancreatic glucokinase regulates its cellular stability and activity.
J Biol Chem
; 288(8): 5951-62, 2013 Feb 22.
Article
in English
| MEDLINE | ID: mdl-23297408
2.
GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation.
Biochim Biophys Acta
; 1822(11): 1705-15, 2012 Nov.
Article
in English
| MEDLINE | ID: mdl-22820548
3.
Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease.
J Biol Chem
; 286(40): 34593-605, 2011 Oct 07.
Article
in English
| MEDLINE | ID: mdl-21784842
4.
Heterotetrameric forms of human phenylalanine hydroxylase: co-expression of wild-type and mutant forms in a bicistronic system.
Biochim Biophys Acta
; 1812(5): 602-12, 2011 May.
Article
in English
| MEDLINE | ID: mdl-21315150
5.
Phenylketonuria as a protein misfolding disease: The mutation pG46S in phenylalanine hydroxylase promotes self-association and fibril formation.
Biochim Biophys Acta
; 1812(1): 106-20, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-20937381
6.
The G46S-hPAH mutant protein: a model to study the rescue of aggregation-prone PKU mutations by chaperones.
Mol Genet Metab
; 104 Suppl: S40-4, 2011.
Article
in English
| MEDLINE | ID: mdl-21871828
7.
Catalytic activation of human glucokinase by substrate binding: residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions.
FEBS J
; 275(10): 2467-81, 2008 May.
Article
in English
| MEDLINE | ID: mdl-18397317
8.
The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV.
J Mol Biol
; 368(5): 1367-78, 2007 May 18.
Article
in English
| MEDLINE | ID: mdl-17395201
9.
Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA.
Biochim Biophys Acta
; 1763(11): 1325-34, 2006 Nov.
Article
in English
| MEDLINE | ID: mdl-17045350
10.
Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation.
J Mol Biol
; 363(2): 469-81, 2006 Oct 20.
Article
in English
| MEDLINE | ID: mdl-16963080
11.
PKU mutation p.G46S prevents the stereospecific binding of l-phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain.
FEBS Open Bio
; 7(2): 195-203, 2017 02.
Article
in English
| MEDLINE | ID: mdl-28174686
12.
Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation.
FEBS Open Bio
; 7(7): 1026-1036, 2017 07.
Article
in English
| MEDLINE | ID: mdl-28680815
13.
Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation.
Mol Cell Endocrinol
; 454: 146-157, 2017 10 15.
Article
in English
| MEDLINE | ID: mdl-28648619
14.
One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime.
Free Radic Biol Med
; 41(8): 1266-71, 2006 Oct 15.
Article
in English
| MEDLINE | ID: mdl-17015173
15.
Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+.
FEBS J
; 273(3): 513-22, 2006 Feb.
Article
in English
| MEDLINE | ID: mdl-16420475
16.
Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction.
FEBS Lett
; 579(1): 203-6, 2005 Jan 03.
Article
in English
| MEDLINE | ID: mdl-15620714
17.
Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation.
J Mol Biol
; 320(5): 1095-108, 2002 Jul 26.
Article
in English
| MEDLINE | ID: mdl-12126628
18.
2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding.
J Mol Biol
; 333(4): 747-57, 2003 Oct 31.
Article
in English
| MEDLINE | ID: mdl-14568534
19.
Colocalization of Ca2+-ATPase and GRP94 with p58 and the effects of thapsigargin on protein recycling suggest the participation of the pre-Golgi intermediate compartment in intracellular Ca2+ storage.
Eur J Cell Biol
; 81(9): 469-83, 2002 Sep.
Article
in English
| MEDLINE | ID: mdl-12416724
20.
Catecholamine metabolism: an update on key biosynthetic enzymes and vesicular monoamine transporters.
Ann N Y Acad Sci
; 971: 69-75, 2002 Oct.
Article
in English
| MEDLINE | ID: mdl-12438092