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1.
Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist.
Mol Pharmacol
; 79(1): 69-76, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-20943773
2.
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.
Nat Cell Biol
; 4(2): 95-105, 2002 Feb.
Article
in English
| MEDLINE | ID: mdl-11788820
3.
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.
Bioorg Med Chem Lett
; 21(1): 288-93, 2011 Jan 01.
Article
in English
| MEDLINE | ID: mdl-21106375
4.
Identification of distinct plasma biomarker signatures in patients with rapid and slow declining forms of COPD.
COPD
; 7(1): 51-8, 2010 Feb.
Article
in English
| MEDLINE | ID: mdl-20214463
5.
High-sensitivity nanoLC-MS/MS analysis of urinary desmosine and isodesmosine.
Anal Chem
; 81(5): 1881-7, 2009 Mar 01.
Article
in English
| MEDLINE | ID: mdl-19178285
6.
Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists.
Bioorg Med Chem Lett
; 19(19): 5741-5, 2009 Oct 01.
Article
in English
| MEDLINE | ID: mdl-19713110
7.
The C3a receptor antagonist SB 290157 has agonist activity.
Immunol Lett
; 100(2): 139-45, 2005 Sep 15.
Article
in English
| MEDLINE | ID: mdl-16154494
8.
Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2.
Br J Pharmacol
; 137(8): 1163-72, 2002 Dec.
Article
in English
| MEDLINE | ID: mdl-12466225
9.
Expression of prostaglandin D synthase and the prostaglandin D2 receptors DP and CRTH2 in human nasal mucosa.
Prostaglandins Other Lipid Mediat
; 73(1-2): 87-101, 2004 Jan.
Article
in English
| MEDLINE | ID: mdl-15165034
10.
Anti-inflammatory actions of Chemoattractant Receptor-homologous molecule expressed on Th2 by the antagonist MK-7246 in a novel rat model of Alternaria alternata elicited pulmonary inflammation.
Eur J Pharmacol
; 743: 106-16, 2014 Nov 15.
Article
in English
| MEDLINE | ID: mdl-25261040
11.
Caspase-3 cleaves the formin-homology-domain-containing protein FHOD1 during apoptosis to generate a C-terminal fragment that is targeted to the nucleolus.
Apoptosis
; 11(11): 1863-76, 2006 Nov.
Article
in English
| MEDLINE | ID: mdl-17013756
12.
Identification of a potent and selective synthetic agonist at the CRTH2 receptor.
Mol Pharmacol
; 67(6): 1834-9, 2005 Jun.
Article
in English
| MEDLINE | ID: mdl-15755909
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