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1.
Discovery of MDV6058 (PF-06952229), a selective and potent TGFßR1 inhibitor: Design, synthesis and optimization.
Bioorg Med Chem Lett
; 75: 128979, 2022 11 01.
Article
in English
| MEDLINE | ID: mdl-36089110
2.
Comparative Analyses of Poly(ADP-Ribose) Polymerase Inhibitors.
Int J Toxicol
; 41(6): 442-454, 2022 12.
Article
in English
| MEDLINE | ID: mdl-35989659
3.
Enzalutamide and Apalutamide: In Vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy Model.
Chem Res Toxicol
; 33(1): 211-222, 2020 01 21.
Article
in English
| MEDLINE | ID: mdl-31538772
4.
Salt Selection Matters: Differential Renal Toxicity With MDV1634.Maleate Versus MDV1634.2HCl.
Int J Toxicol
; 36(3): 207-219, 2017.
Article
in English
| MEDLINE | ID: mdl-28466691
5.
The impact of dasatinib on pregnancy outcomes.
Am J Hematol
; 90(12): 1111-5, 2015 Dec.
Article
in English
| MEDLINE | ID: mdl-26348106
6.
Clinical features of pulmonary arterial hypertension in patients receiving dasatinib.
Am J Hematol
; 90(11): 1060-4, 2015 Nov.
Article
in English
| MEDLINE | ID: mdl-26284693
7.
Improved ruggedness of an ion-pairing liquid chromatography/tandem mass spectrometry assay for the quantitative analysis of the triphosphate metabolite of a nucleoside reverse transcriptase inhibitor in peripheral blood mononuclear cells.
Rapid Commun Mass Spectrom
; 27(3): 481-8, 2013 Feb 15.
Article
in English
| MEDLINE | ID: mdl-23280981
8.
Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5.
Bioorg Med Chem Lett
; 20(19): 5718-21, 2010 Oct 01.
Article
in English
| MEDLINE | ID: mdl-20801037
9.
Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes.
FASEB J
; 21(12): 3355-68, 2007 Oct.
Article
in English
| MEDLINE | ID: mdl-17554073
10.
In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension.
Cancer Chemother Pharmacol
; 79(4): 711-723, 2017 04.
Article
in English
| MEDLINE | ID: mdl-28283735
11.
High glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells.
Diabetes
; 52(5): 1256-64, 2003 May.
Article
in English
| MEDLINE | ID: mdl-12716761
12.
Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability.
J Leukoc Biol
; 76(1): 145-51, 2004 Jul.
Article
in English
| MEDLINE | ID: mdl-15075360
13.
Assessment of biomarkers of drug-induced kidney injury in cynomolgus monkeys treated with a triple reuptake inhibitor.
Toxicol Sci
; 120(2): 269-83, 2011 Apr.
Article
in English
| MEDLINE | ID: mdl-21258088
14.
Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice.
Am J Respir Cell Mol Biol
; 36(3): 276-85, 2007 Mar.
Article
in English
| MEDLINE | ID: mdl-16990616
15.
Inhaled CD86 antisense oligonucleotide suppresses pulmonary inflammation and airway hyper-responsiveness in allergic mice.
J Pharmacol Exp Ther
; 321(3): 938-46, 2007 Jun.
Article
in English
| MEDLINE | ID: mdl-17389243
16.
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells.
J Biol Chem
; 277(35): 32124-32, 2002 Aug 30.
Article
in English
| MEDLINE | ID: mdl-12052830
17.
Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model.
Blood
; 101(10): 3940-7, 2003 May 15.
Article
in English
| MEDLINE | ID: mdl-12543866
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