Search | VHL CLAP/WR-PAHO/WHO

1.

Kinases charging to the membrane.

Hadders, Michael A; Williams, Roger L.

Cell ; 143(6): 865-7, 2010 Dec 10.

Article in English | MEDLINE | ID: mdl-21145452

2.

Delineation of a KDM2B-related neurodevelopmental disorder and its associated DNA methylation signature.

van Jaarsveld, Richard H; Reilly, Jack; Cornips, Marie-Claire; Hadders, Michael A; Agolini, Emanuele; Ahimaz, Priyanka; Anyane-Yeboa, Kwame; Bellanger, Severine Audebert; van Binsbergen, Ellen; van den Boogaard, Marie-Jose; Brischoux-Boucher, Elise; Caylor, Raymond C; Ciolfi, Andrea; van Essen, Ton A J; Fontana, Paolo; Hopman, Saskia; Iascone, Maria; Javier, Margaret M; Kamsteeg, Erik-Jan; Kerkhof, Jennifer; Kido, Jun; Kim, Hyung-Goo; Kleefstra, Tjitske; Lonardo, Fortunato; Lai, Abbe; Lev, Dorit; Levy, Michael A; Lewis, M E Suzanne; Lichty, Angie; Mannens, Marcel M A M; Matsumoto, Naomichi; Maya, Idit; McConkey, Haley; Megarbane, Andre; Michaud, Vincent; Miele, Evelina; Niceta, Marcello; Novelli, Antonio; Onesimo, Roberta; Pfundt, Rolph; Popp, Bernt; Prijoles, Eloise; Relator, Raissa; Redon, Sylvia; Rots, Dmitrijs; Rouault, Karen; Saida, Ken; Schieving, Jolanda; Tartaglia, Marco; Tenconi, Romano.

Genet Med ; 25(1): 49-62, 2023 01.

Article in English | MEDLINE | ID: mdl-36322151

3.

A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis.

Ueki, Yumi; Hadders, Michael A; Weisser, Melanie B; Nasa, Isha; Sotelo-Parrilla, Paula; Cressey, Lauren E; Gupta, Tanmay; Hertz, Emil P T; Kruse, Thomas; Montoya, Guillermo; Jeyaprakash, A Arockia; Kettenbach, Arminja; Lens, Susanne M A; Nilsson, Jakob.

EMBO Rep ; 22(7): e52295, 2021 07 05.

Article in English | MEDLINE | ID: mdl-33973335

4.

Sequential multisite phospho-regulation of KNL1-BUB3 interfaces at mitotic kinetochores.

Vleugel, Mathijs; Omerzu, Manja; Groenewold, Vincent; Hadders, Michael A; Lens, Susanne M A; Kops, Geert J P L.

Mol Cell ; 57(5): 824-835, 2015 Mar 05.

Article in English | MEDLINE | ID: mdl-25661489

5.

Structure-guided design of selective Epac1 and Epac2 agonists.

Schwede, Frank; Bertinetti, Daniela; Langerijs, Carianne N; Hadders, Michael A; Wienk, Hans; Ellenbroek, Johanne H; de Koning, Eelco J P; Bos, Johannes L; Herberg, Friedrich W; Genieser, Hans-Gottfried; Janssen, Richard A J; Rehmann, Holger.

PLoS Biol ; 13(1): e1002038, 2015 Jan.

Article in English | MEDLINE | ID: mdl-25603503

6.

ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes.

Hadders, Michael A; Agromayor, Monica; Obita, Takayuki; Perisic, Olga; Caballe, Anna; Kloc, Magdalena; Lamers, Meindert H; Williams, Roger L; Martin-Serrano, Juan.

Proc Natl Acad Sci U S A ; 109(43): 17424-9, 2012 Oct 23.

Article in English | MEDLINE | ID: mdl-23045692

7.

Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B.

Rehmann, Holger; Arias-Palomo, Ernesto; Hadders, Michael A; Schwede, Frank; Llorca, Oscar; Bos, Johannes L.

Nature ; 455(7209): 124-7, 2008 Sep 04.

Article in English | MEDLINE | ID: mdl-18660803

8.

Changing places: Chromosomal Passenger Complex relocation in early anaphase.

Hadders, Michael A; Lens, Susanne M A.

Trends Cell Biol ; 32(2): 165-176, 2022 02.

Article in English | MEDLINE | ID: mdl-34663523

9.

Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC.

Abad, Maria Alba; Gupta, Tanmay; Hadders, Michael A; Meppelink, Amanda; Wopken, J Pepijn; Blackburn, Elizabeth; Zou, Juan; Gireesh, Anjitha; Buzuk, Lana; Kelly, David A; McHugh, Toni; Rappsilber, Juri; Lens, Susanne M A; Jeyaprakash, A Arockia.

J Cell Biol ; 221(8)2022 08 01.

Article in English | MEDLINE | ID: mdl-35776132

10.

Delaying the final cut: A close encounter of checkpoint kinases at the midbody.

Hadders, Michael A; Lens, Susanne M A.

J Cell Biol ; 220(2)2021 02 01.

Article in English | MEDLINE | ID: mdl-33404606

11.

Leave no sister behind.

Hadders, Michael A; Lens, Susanne M A.

Cell Rep ; 37(7): 110053, 2021 11 16.

Article in English | MEDLINE | ID: mdl-34788613

12.

A Newborn Falsely Suspected of Congenital Hypothyroidism due to Mutated Thyroxine-Binding Globulin with Low Binding Affinity.

Hengeveld, Rutger C C; Albersen, Monique; Hadders, Michael A H; Hellinga, Ilse; Bikker, Hennie; Heijboer, Annemieke C; Paul van Trotsenburg, A S; Hillebrand, Jacquelien J; Boelen, Anita; Zwaveling-Soonawala, Nitash.

Horm Res Paediatr ; 94(1-2): 76-80, 2021.

Article in English | MEDLINE | ID: mdl-34126618

13.

Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis.

Hadders, Michael A; Hindriksen, Sanne; Truong, My Anh; Mhaskar, Aditya N; Wopken, J Pepijn; Vromans, Martijn J M; Lens, Susanne M A.

J Cell Biol ; 219(3)2020 03 02.

Article in English | MEDLINE | ID: mdl-32027339

14.

Fifteen novel mutations in PKLR associated with pyruvate kinase (PK) deficiency: structural implications of amino acid substitutions in PK.

van Wijk, Richard; Huizinga, Eric G; van Wesel, Annet C W; van Oirschot, Brigitte A; Hadders, Michael A; van Solinge, Wouter W.

Hum Mutat ; 30(3): 446-53, 2009 Mar.

Article in English | MEDLINE | ID: mdl-19085939

15.

The Ins and Outs of Aurora B Inner Centromere Localization.

Hindriksen, Sanne; Lens, Susanne M A; Hadders, Michael A.

Front Cell Dev Biol ; 5: 112, 2017.

Article in English | MEDLINE | ID: mdl-29312936

16.

Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing.

Hengeveld, Rutger C C; Vromans, Martijn J M; Vleugel, Mathijs; Hadders, Michael A; Lens, Susanne M A.

Nat Commun ; 8: 15542, 2017 05 31.

Article in English | MEDLINE | ID: mdl-28561035

17.

Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells.

Hindriksen, Sanne; Bramer, Arne J; Truong, My Anh; Vromans, Martijn J M; Post, Jasmin B; Verlaan-Klink, Ingrid; Snippert, Hugo J; Lens, Susanne M A; Hadders, Michael A.

PLoS One ; 12(6): e0179514, 2017.

Article in English | MEDLINE | ID: mdl-28640891

18.

Inter-domain Cooperation in INCENP Promotes Aurora B Relocation from Centromeres to Microtubules.

van der Horst, Armando; Vromans, Martijn J M; Bouwman, Kim; van der Waal, Maike S; Hadders, Michael A; Lens, Susanne M A.

Cell Rep ; 12(3): 380-7, 2015 Jul 21.

Article in English | MEDLINE | ID: mdl-26166576

19.

Detailed imaging and genetic analysis reveal a secondary BRAF(L505H) resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib.

Hoogstraat, Marlous; Gadellaa-van Hooijdonk, Christa G; Ubink, Inge; Besselink, Nicolle J M; Pieterse, Mark; Veldhuis, Wouter; van Stralen, Marijn; Meijer, Eelco F J; Willems, Stefan M; Hadders, Michael A; Kuilman, Thomas; Krijgsman, Oscar; Peeper, Daniel S; Koudijs, Marco J; Cuppen, Edwin; Voest, Emile E; Lolkema, Martijn P.

Pigment Cell Melanoma Res ; 28(3): 318-23, 2015 May.

Article in English | MEDLINE | ID: mdl-25515853

20.

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Hadders, Michael A; Bubeck, Doryen; Roversi, Pietro; Hakobyan, Svetlana; Forneris, Federico; Morgan, B Paul; Pangburn, Michael K; Llorca, Oscar; Lea, Susan M; Gros, Piet.

Cell Rep ; 1(3): 200-7, 2012 Mar 29.

Article in English | MEDLINE | ID: mdl-22832194

VHL CLAP/WR-PAHO/WHO

Latin-American Center for Perinatology, Woman and Reproductive Health

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Kinases charging to the membrane.

Delineation of a KDM2B-related neurodevelopmental disorder and its associated DNA methylation signature.

A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis.

Sequential multisite phospho-regulation of KNL1-BUB3 interfaces at mitotic kinetochores.

Structure-guided design of selective Epac1 and Epac2 agonists.

ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes.

Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B.

Changing places: Chromosomal Passenger Complex relocation in early anaphase.

Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC.

Delaying the final cut: A close encounter of checkpoint kinases at the midbody.

Leave no sister behind.

A Newborn Falsely Suspected of Congenital Hypothyroidism due to Mutated Thyroxine-Binding Globulin with Low Binding Affinity.

Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis.

Fifteen novel mutations in PKLR associated with pyruvate kinase (PK) deficiency: structural implications of amino acid substitutions in PK.

The Ins and Outs of Aurora B Inner Centromere Localization.

Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing.

Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells.

Inter-domain Cooperation in INCENP Promotes Aurora B Relocation from Centromeres to Microtubules.

Detailed imaging and genetic analysis reveal a secondary BRAF(L505H) resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib.

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.