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1.
NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation.
Nat Methods
; 19(2): 205-215, 2022 02.
Article
in English
| MEDLINE | ID: mdl-35132245
2.
A Conserved Second Sphere Residue Tunes Copper Site Reactivity in Lytic Polysaccharide Monooxygenases.
J Am Chem Soc
; 145(34): 18888-18903, 2023 08 30.
Article
in English
| MEDLINE | ID: mdl-37584157
3.
Primordial-like enzymes from bacteria with reduced genomes.
Mol Microbiol
; 105(4): 508-524, 2017 Aug.
Article
in English
| MEDLINE | ID: mdl-28640457
4.
Evaluation of NfsA-like nitroreductases from Neisseria meningitidis and Bartonella henselae for enzyme-prodrug therapy, targeted cellular ablation, and dinitrotoluene bioremediation.
Biotechnol Lett
; 40(2): 359-367, 2018 Feb.
Article
in English
| MEDLINE | ID: mdl-29147875
5.
Impact of the Copper Second Coordination Sphere on Catalytic Performance and Substrate Specificity of a Bacterial Lytic Polysaccharide Monooxygenase.
ACS Omega
; 9(21): 23040-23052, 2024 May 28.
Article
in English
| MEDLINE | ID: mdl-38826537
6.
Mutational dissection of a hole hopping route in a lytic polysaccharide monooxygenase (LPMO).
Nat Commun
; 15(1): 3975, 2024 May 10.
Article
in English
| MEDLINE | ID: mdl-38729930
7.
Reductants fuel lytic polysaccharide monooxygenase activity in a pH-dependent manner.
FEBS Lett
; 597(10): 1363-1374, 2023 05.
Article
in English
| MEDLINE | ID: mdl-37081294
8.
Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.
Elife
; 102021 06 29.
Article
in English
| MEDLINE | ID: mdl-34184634
9.
Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues.
Elife
; 92020 11 13.
Article
in English
| MEDLINE | ID: mdl-33185191
10.
Total Synthesis and Bioactivity Studies of Fungal Metabolite (-)-TAN-2483B.
Org Lett
; 22(24): 9427-9432, 2020 12 18.
Article
in English
| MEDLINE | ID: mdl-33232161
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