Search details
1.
BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Cell
; 146(6): 904-17, 2011 Sep 16.
Article
in English
| MEDLINE | ID: mdl-21889194
2.
SMARCB1 regulates the hypoxic stress response in sickle cell trait.
Proc Natl Acad Sci U S A
; 120(21): e2209639120, 2023 05 23.
Article
in English
| MEDLINE | ID: mdl-37186844
3.
Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer.
Nature
; 568(7752): 410-414, 2019 04.
Article
in English
| MEDLINE | ID: mdl-30918400
4.
Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.
Nature
; 542(7641): 362-366, 2017 02 16.
Article
in English
| MEDLINE | ID: mdl-28178232
5.
Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer.
Gastroenterology
; 161(1): 196-210, 2021 07.
Article
in English
| MEDLINE | ID: mdl-33745946
6.
Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.
Cancer Immunol Immunother
; 70(4): 1101-1113, 2021 Apr.
Article
in English
| MEDLINE | ID: mdl-33123754
7.
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Nature
; 514(7524): 628-32, 2014 Oct 30.
Article
in English
| MEDLINE | ID: mdl-25119024
8.
Melanoma genome sequencing reveals frequent PREX2 mutations.
Nature
; 485(7399): 502-6, 2012 May 09.
Article
in English
| MEDLINE | ID: mdl-22622578
9.
Telomere dysfunction induces metabolic and mitochondrial compromise.
Nature
; 470(7334): 359-65, 2011 Feb 17.
Article
in English
| MEDLINE | ID: mdl-21307849
10.
Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.
Proc Natl Acad Sci U S A
; 108(33): 13716-21, 2011 Aug 16.
Article
in English
| MEDLINE | ID: mdl-21844338
11.
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types.
Clin Cancer Res
; 30(10): 2121-2139, 2024 May 15.
Article
in English
| MEDLINE | ID: mdl-38416404
12.
Combined KRASG12C and SOS1 inhibition enhances and extends the anti-tumor response in KRASG12C-driven cancers by addressing intrinsic and acquired resistance.
bioRxiv
; 2023 Jan 23.
Article
in English
| MEDLINE | ID: mdl-36747713
13.
Oncogenic Kras G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 + T cells dependent manner.
bioRxiv
; 2023 Feb 18.
Article
in English
| MEDLINE | ID: mdl-36824971
14.
KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells.
Cancer Cell
; 41(9): 1606-1620.e8, 2023 09 11.
Article
in English
| MEDLINE | ID: mdl-37625401
15.
Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy.
Clin Transl Med
; 13(5): e1267, 2023 05.
Article
in English
| MEDLINE | ID: mdl-37226898
16.
Evolutionary fingerprints of EMT in pancreatic cancers.
bioRxiv
; 2023 Sep 19.
Article
in English
| MEDLINE | ID: mdl-37786705
17.
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.
Nat Med
; 29(1): 115-126, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36658425
18.
Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer.
Nat Cancer
; 4(7): 984-1000, 2023 07.
Article
in English
| MEDLINE | ID: mdl-37365326
19.
Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set.
JCO Clin Cancer Inform
; 6: e2200040, 2022 07.
Article
in English
| MEDLINE | ID: mdl-35944232
20.
Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations.
Oncogene
; 40(26): 4425-4439, 2021 07.
Article
in English
| MEDLINE | ID: mdl-34108622